Inhibition of the METTL3/m6A/miR-34a-5p axis suppresses trigeminovascular activation in nitroglycerin-induced migraine via the Wnt/β-catenin pathway [0.03%]
抑制METTL3/m6A/miR-34a-5p轴通过Wnt/β-catenin途径抑制硝酸甘油诱导的偏头痛中的三叉血管激活
Hui Zhang,Minming Shao,Feng Zhang et al.
Hui Zhang et al.
Background: Neuroinflammation is a key driver of migraine pathogenesis, particularly by promoting neuronal sensitization. METTL3-mediated m6A methylation has emerged as a critical epigenetic regulator in neuroinflammatory...
Inhibition of the METTL3/m6A/miR-34a-5p axis suppresses trigeminovascular activation in nitroglycerin-induced migraine via the Wnt/β-catenin pathway [0.03%]
METTL3/m6A/miR-34a-5p轴的抑制通过Wnt/β-连环蛋白通路抑制硝酸甘油诱导的偏头痛中的三叉血管激活
Hui Zhang,Minming Shao,Feng Zhang et al.
Hui Zhang et al.
Background: Neuroinflammation is a key driver of migraine pathogenesis, particularly by promoting neuronal sensitization. METTL3-mediated m6A methylation has emerged as a critical epigenetic regulator in neuroinflammatory...
Application of machine learning in migraine classification: a call for study design standardization and global collaboration [0.03%]
机器学习在偏头痛分类中的应用：研究设计标准化和全球合作的呼吁
Igor Petrušić,Roberta Messina,Lanfranco Pellesi et al.
Igor Petrušić et al.
Migraine is a complex neurological disorder with diverse clinical phenotypes and a multifaceted pathophysiology, which poses substantial challenges for accurate diagnosis, subtype differentiation, and biomarker discovery. Machine learning (...
Application of machine learning in migraine classification: a call for study design standardization and global collaboration [0.03%]
机器学习在偏头痛分类中的应用：研究设计标准化和全球协作的呼吁
Igor Petrušić,Roberta Messina,Lanfranco Pellesi et al.
Igor Petrušić et al.
Migraine is a complex neurological disorder with diverse clinical phenotypes and a multifaceted pathophysiology, which poses substantial challenges for accurate diagnosis, subtype differentiation, and biomarker discovery. Machine learning (...
Ergotamine and triptans induced medication-overuse headache: a real-world population-based comparative study from the Northern Thai headache registry [0.03%]
麦角胺和曲普坦类药物引起的药物过度使用性头痛：来自泰国北部头痛登记中心的大型真实世界研究
Surat Tanprawate,Kitti Thiankhaw,Watthikorn Chusilthong et al.
Surat Tanprawate et al.
Background: Medication-overuse headache (MOH) remains a leading cause of chronic daily headache globally. Although triptans are the predominant implicated in high-income countries, ergotamine continues to be widely used i...
Comparative Study
The journal of headache and pain. 2025 Oct 2;26(1):198. DOI:10.1186/s10194-025-02161-6 2025
Ergotamine and triptans induced medication-overuse headache: a real-world population-based comparative study from the Northern Thai headache registry [0.03%]
麦角胺及曲普坦类药物引发的药物过量性头痛：来自泰国北部头痛登记中心的真实世界队列研究
Surat Tanprawate,Kitti Thiankhaw,Watthikorn Chusilthong et al.
Surat Tanprawate et al.
Background: Medication-overuse headache (MOH) remains a leading cause of chronic daily headache globally. Although triptans are the predominant implicated in high-income countries, ergotamine continues to be widely used i...
Comparative Study
The journal of headache and pain. 2025 Oct 2;26(1):198. DOI:10.1186/s10194-025-02161-6 2025
CREB-KIF1A-CGRP-positive feedback loop drives central sensitization in chronic migraine [0.03%]
CREB-KIF1A-CGRP正反馈环路驱动慢性偏头痛中枢敏化
Wei Jiang,Peng Yu,Yan-Min Shi et al.
Wei Jiang et al.
Background: Chronic migraine (CM), defined as ≥ 15 monthly headache days and often involving central sensitization, is a complex neurological disorder. While calcitonin gene-related peptide (CGRP) is a key migraine targe...
Neural oscillation mechanisms of repetitive subconcussive impacts: a network study of microstate-specific cross-frequency coupling [0.03%]
重复亚冲打击的神经振荡机制：微状态特异性跨频率耦合的网络研究
He Yida,Li Huanhuan,Li Xiang et al.
He Yida et al.
Background: Repetitive subconcussive impacts are linked to headache pathophysiology, yet the role of electroencephalography (EEG) microstates and cross-frequency coupling in repetitive subconcussive (SC) neural alteration...
Dissecting immune cell-specific genetics in migraine: a multi-omics framework for target discovery and therapeutic prioritization [0.03%]
migraine的免疫细胞特异性遗传解析：靶点发现和治疗优先级设定的多组学框架
Yanggang Hong,Yuze Mi,Feng Chen et al.
Yanggang Hong et al.
Background: Migraine is a highly prevalent neurological disorder with complex pathophysiology and limited treatment efficacy. Emerging evidence suggests immune cell involvement in migraine, but the specific regulatory mec...
Artificial intelligence in headache medicine: between automation and the doctor-patient relationship. A systematic review [0.03%]
人工智能在头痛医学中的应用：自动化与医患关系之间的平衡。系统性综述
Christian Espinoza-Vinces,Marlon Cantillo Martínez,Ainhoa Atorrasagasti-Villar et al.
Christian Espinoza-Vinces et al.
Background: Headache disorders, particularly migraine, are highly prevalent, but often remain underdiagnosed and undertreated. Artificial intelligence (AI) offers promising applications in diagnosis, prediction of attacks...