Uncovering longitudinal changes in the brain functional connectome along the migraine cycle: a multilevel clinical connectome fingerprinting framework [0.03%]
沿偏头痛周期脑功能连接组纵向变化的发现:一种多水平临床连接组指纹框架
Inês Esteves,Ana R Fouto,Amparo Ruiz-Tagle et al.
Inês Esteves et al.
Background: Changes in large-scale brain networks have been reported in migraine patients, but it remains unclear how these manifest in the various phases of the migraine cycle. Case-control fMRI studies spanning the enti...
Diana Doukhi,Stéphanie Debette,Jérome Mawet
Diana Doukhi
Headache is a common neurological symptom, often leading to the investigation of secondary causes, including cerebrovascular conditions such as cranial and cervical artery dissection (CCAD). CCAD, a significant cause of stroke in younger ad...
Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache [0.03%]
自发性直立性头痛的颅内压监测
Linda DAntona,Sanjay Cheema,Dwij Mehta et al.
Linda DAntona et al.
Background: Spontaneous intracranial hypotension (SIH) is a debilitating disorder, with an estimated annual incidence of 3.7 per 100,000. Diagnosing SIH can be challenging for clinicians, as patients frequently present wi...
Observational Study
The journal of headache and pain. 2025 Feb 4;26(1):27. DOI:10.1186/s10194-024-01928-7 2025
Epidemiology of clinically significant migraine in Israel: a retrospective database study [0.03%]
以色列临床显著性偏头痛的流行病学特征:回顾性数据库研究
A Shifrin,E Domany,M Tirosh et al.
A Shifrin et al.
Background: Epidemiological studies on migraine are valuable for tracking disease trends, identifying risk factors, and informing treatment strategies. This study assessed the prevalence and annual incidence of clinically...
The link between spreading depolarization and innate immunity in the central nervous system [0.03%]
扩散去极化与中枢神经系统先天免疫之间的联系
Kadir Oguzhan Soylu,Muge Yemisci,Hulya Karatas
Kadir Oguzhan Soylu
Spreading depolarization (SD) is a complex event that induces significant cellular stress in the central nervous system, leading to a robust inflammatory response without causing cell death in healthy tissues which may be called as neuro-pa...
Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis [0.03%]
他汀类药物的使用与HMGC-CoA还原酶抑制和偏头痛发作关联性的系统综述及meta分析研究
Hamdy A Makhlouf,Amr K Hassan,Nereen A Almosilhy et al.
Hamdy A Makhlouf et al.
Background: Statins or 3‑hydroxy‑3‑methyl‑glutarylcoenzyme A (HMG‑CoA) reductase inhibitors are medications that act by reducing the cholesterol content of liver cells Moreover, statins have been found to improve end...
Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab [0.03%]
一项长期三期加尼珠单抗研究中慢性偏头痛转换至发作性偏头痛的频率变化
Hans-Christoph Diener,Kathleen A Day,Sarah Lipsius et al.
Hans-Christoph Diener et al.
Background: Chronic migraine (CM) is a highly disabling form of migraine in which patients have ≥ 15 headache days per month, of which at least 8 have the features of migraine. Galcanezumab is a monoclonal antibody to ca...
Fitness-to-work considerations in the paradigmatic pain condition of headache disorder [0.03%]
头痛障碍范式性疼痛疾病的上岗体检问题考虑因素
Xiangning Fan,Ellina Lytvyak,Charl Els et al.
Xiangning Fan et al.
Headache disorders are common, including in the working population. Clinicians caring for patients with headache need to be aware of work-related factors as potential causes or triggers of headache disorders, and consider the impact of head...
Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success [0.03%]
血清素受体抑制剂治疗难治性发作性头痛患者:一项观察性研究和病例报告
Lanfranco Pellesi,Lars Edvinsson
Lanfranco Pellesi
Substance P, previously dismissed as a therapeutic target for migraine due to the failure of neurokinin-1 receptor antagonists, warrants renewed attention. Building on the success of therapies targeting the calcitonin gene-related peptide (...