Cerebellar neurocan gene expression is a common pathogenic factor of trigeminal neuralgia and depression [0.03%]
小脑神经粘连蛋白基因表达是三叉神經痛和抑郁的共同致病因素
Zhangying Zeng,Jianwei Jiang,Xuemei Wu et al.
Zhangying Zeng et al.
The role of gut microbiota in neuropathic pain: insights into immune mechanisms [0.03%]
肠道菌群在神经痛中的作用:免疫机制的启示
Zexiong Gong,Jipeng Zou,Yuxiang Fang et al.
Zexiong Gong et al.
Neuropathic pain (NP), characterized by its complex pathophysiological mechanisms, has long posed a formidable therapeutic challenge. The burden of NP is further exacerbated by the increasing prevalence of chronic diseases. Emerging evidenc...
Risk factors associated to disability in primary headaches: a systematic review to inform future iterations of the Global Burden of Disease Study [0.03%]
与原发性头痛相关的致残因素:用于未来全球疾病负担研究的系统评价
Alberto Raggi,Matteo Castaldo,Chia-Chun Chiang et al.
Alberto Raggi et al.
Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models [0.03%]
小胶质细胞和iNOS参与了前列腺素和重复应激在鼠性头痛模型中的作用
Hao-Ruei Mei,Bianca Mason,Ya-Yu Hu et al.
Hao-Ruei Mei et al.
Background: Migraine impacts 15% of the global population, predominantly women. Previous studies have shown a role for prolactin in animal migraine models induced by either stimulation of the dura mater or repeated stress...
From trigeminal ganglion to cortex: ATG7 emerges as a key integrator of migraine pathways via multi-omics profiling [0.03%]
从三叉神经节到皮层:多组学分析揭示自噬相关基因7是偏头痛的关键调节因子
Chengcheng Zhang,Yine Song,Baicheng Cao et al.
Chengcheng Zhang et al.
Background: Migraine is a complex neurological disorder with poorly understood molecular mechanisms. Despite advances in genetic and omics research, the shared mechanisms between central and peripheral nervous systems in ...
A mouse model of classical trigeminal neuralgia via intradural compression of the trigeminal nerve [0.03%]
三叉神经根脱髓鞘的经典型三叉神经痛小鼠模型及其机制研究
Mostafa W Abdulrahim,Yanxia Chen,Sumil K Nair et al.
Mostafa W Abdulrahim et al.
Gabriele Sebastianelli,Woo-Seok Ha,Roberta Messina et al.
Gabriele Sebastianelli et al.
Effectiveness of rimegepant in vestibular migraine: a prospective self-controlled cohort study [0.03%]
关于偏头痛性眩晕的疗效:一项前瞻性自身对照队列研究
Jinyan Shao,Jingxin Fu,Mengting Zhou et al.
Jinyan Shao et al.
Long-term effectiveness of fremanezumab in episodic and chronic migraine patients in clinical routine - 24-months results from the prospective non-interventional FINESSE study [0.03%]
卡博利珠单抗治疗偏头痛发作和慢性偏头痛患者长期疗效的临床常规结果——前瞻性非干预性FINESSE研究24个月的结果分析
Andreas Straube,Gregor Broessner,Charly Gaul et al.
Andreas Straube et al.
Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity [0.03%]
施万细胞Lrp1缺失通过调节线粒体功能和TRPV1 / TRPA1活性驱动三叉神经元过敏和口面痛
Zhiting Gong,Morgan Zhang,Naijiang Liu et al.
Zhiting Gong et al.
Background: Orofacial pain, affecting 10-15% of adults, is a prevalent form of chronic pain that remains a major clinical challenge. The Schwann cell involvement in this pathophysiology is not fully understood. Low-densit...