The role and interaction of hypothalamic-related neurotransmitters in migraine [0.03%]
与偏头痛相关的下丘脑相关神经递质的作用及相互作用
Ana Belen Salinas-Abarca,Mohammed Gamal-Eltrabily,Marcela Romero-Reyes et al.
Ana Belen Salinas-Abarca et al.
Migraine is a complex neurological disorder frequently associated with hypothalamic dysfunction. This brain region is essential for maintaining homeostasis due to its regulation of autonomic, endocrine, and circadian systems. While the path...
Peter Petschner,Sahel Kumar,Duc A Nguyen et al.
Peter Petschner et al.
Background: The present study aimed to deliver a replicable transcriptomic map of migraine without aura (MO) and its comprehensive, genome- and drug discovery focused analysis to identify hypotheses for future research- a...
Correction: Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU‑005 reduces ex vivo cortical spreading depression [0.03%]
订正：AKU-005通过抑制内源大麻素降解酶MAGL、FAAH和ABHD6减少皮质弥散性电抑制作用
Flavia Brugia,Konstantin Ivanov,Auni Aroviita et al.
Flavia Brugia et al.
Published Erratum
The journal of headache and pain. 2025 May 12;26(1):111. DOI:10.1186/s10194-025-02053-9 2025
Altered aminoacid and lipid metabolism in a rat orofacial inflammation model determined by omics approach: potential role in trigeminal sensitisation [0.03%]
组学方法确定的大鼠口腔面部炎性模型中氨基酸和脂类代谢改变：在外周三叉神经敏化中的潜在作用
Krisztina Takács-Lovász,Timea Aczél,Violetta Mohos et al.
Krisztina Takács-Lovász et al.
Background: Trigeminal activation and sensitisation involved in chronic inflammatory orofacial pain share several similarities with headaches, including migraine. Therefore, understanding the pathophysiological mechanisms...
Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation [0.03%]
抑制S100A4减少神经毒性星形胶质细胞活化并通过TLR4/NF-κB途径减轻脊神经结扎大鼠模型的神经病理性疼痛
Tao Xue,Yu Song,Jie Zhao et al.
Tao Xue et al.
S100A4 participates in inflammation and immune reactions in the central nervous system and is involved in the pathogenesis of multiple neurological disorders. It can affect the functions of astrocytes, microglia, infiltrating cells and neur...
Tolerability of repetitive dihydroergotamine infusions paired with an adjustment in preventive treatment strategy in chronic headache disorders in children and youth [0.03%]
重复使用二氢麦角胺配伍调整预防治疗方案在儿童和青年慢性头痛疾病中的耐受性
Sara Pavitt,Cynthia Morris,Lauren Shin et al.
Sara Pavitt et al.
Background: In adults, intravenous (IV) dihydroergotamine (DHE) has been shown to be effective at improving medium term outcomes in patients with chronic headache disorders. The IV formulation is utilized given its superi...
Signaling pathways and molecular mechanisms involved in the onset and progression of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL); a focus on Notch3 signaling [0.03%]
脑外蘘显性动脉病伴皮质下梗死和白质脑病(CADASIL)发病及进展的信号通路及分子机制；重点为Notch3信号转导
Parasta Heidari,Motahareh Taghizadeh,Omid Vakili
Parasta Heidari
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal-dominantly inherited cerebral small-vessel disease (SVD). CADASIL has diverse clinical features such as migraine with aura,...
Calcitonin gene-related peptide in newly diagnosed idiopathic intracranial hypertension: a prospective, cross-sectional, case-control study of cerebrospinal fluid and plasma [0.03%]
新诊断的特发性颅内高压患者降钙素基因相关肽的研究：一项关于脑脊液和血浆的前瞻性病例对照研究
Nadja Skadkær Hansen,Johanne Juhl Korsbaek,Lasse Kristoffer Bak et al.
Nadja Skadkær Hansen et al.
Background: Calcitonin Gene-Related Peptide (CGRP) is involved in migraine pain signaling, and blockage hereof is effective in migraine treatment. Headache in idiopathic intracranial hypertension (IIH) is often migraine-l...
Correction: Uncovering drug targets for cluster headache through proteome-wide Mendelian randomization analysis [0.03%]
纠正：通过蛋白质组范围的孟德尔随机化分析寻找丛集性头痛的药物靶点
Zhonghua Xiong,Zhi Guo,Lei Zhao et al.
Zhonghua Xiong et al.
Published Erratum
The journal of headache and pain. 2025 Apr 29;26(1):94. DOI:10.1186/s10194-025-02032-0 2025
Is there a role of calcitonin gene-related peptide in cortical spreading depression mechanisms?- argument con [0.03%]
钙基因相关肽在皮层扩散性抑制造机制中的作用吗？--反对意见
Agustin Melo-Carrillo
Agustin Melo-Carrillo
Cortical spreading depression (CSD) is a wave of neuronal and glial depolarization followed by suppressed neural activity, thought to underlie migraine aura. While Calcitonin Gene-Related Peptide (CGRP) is well established in migraine patho...