HTLV-1-Driven Clonal Evolution and Immune Escape in Adult T-Cell Leukaemia: From Viral Persistence to Therapeutic Failure [0.03%]
人T细胞白血病病毒1型驱动的成人T细胞白血病中的克隆进化和免疫逃逸：从病毒感染到治疗失败
Zuhair M Mohammedsaleh,Abdullah F Shater
Zuhair M Mohammedsaleh
Adult T-cell leukaemia/lymphoma (ATL) is an aggressive CD4 +T-cell malignancy caused by the human T-cell leukaemia virus type 1 (HTLV-1). Approximately 3%-5% of infected individuals develop ATL after a prolonged latency of 30-50 years, duri...
Comparative Effectiveness of High-Dose and Standard-Dose Influenza Vaccines for Hospitalisation and Mortality in Adults Aged 65 and Older: An Updated Systematic Review and Meta-Analysis [0.03%]
高剂量和标准剂量流感疫苗在65岁及以上成人住院和死亡率方面的有效性比较：一项更新的系统评价和meta分析
Bilal Wazir Khan,Muhammad Huzaifa Khattak,Muhammad Maaz Amjad et al.
Bilal Wazir Khan et al.
This updated systematic review and meta-analysis evaluated the relative vaccine effectiveness (rVE) of high-dose inactivated influenza vaccine (HD-IV) versus standard-dose (SD-IV) in adults ≥ 65 years for key clinical outcomes, including h...
Areli J Navarro,Ignacio A Pasten,Dayesi López-Hernández et al.
Areli J Navarro et al.
Herpes simplex virus type 1 (HSV-1) infection is highly prevalent, with more than 70% of the global population seropositive. HSV-1 commonly infects the skin, eyes, and neurons, as well as immune cells such as dendritic cells; however, an ex...
Tissue Reservoirs of HIV: The Hidden Protective Role of Lymphoid and Myeloid Cells [0.03%]
组织中的HIV库：淋巴和髓样细胞的隐蔽保护作用
Shan He,Akmal Zubair,Ahmed Al-Emam
Shan He
Acquired Immunodeficiency Syndrome (AIDS), caused by the Human Immunodeficiency Virus (HIV), has recently emerged as a significant global health concern. Latently infected lymphocytes, particularly CD4+ T lymphocytes and macrophages, togeth...
SARS-CoV-2 Variants and Immune Evasion: Mapping the Future of Vaccine Design [0.03%]
新冠病毒变异与免疫逃逸：疫苗设计的未来图景
Fatih Uzer,Fulya Erendor,Salih Sanlioglu
Fatih Uzer
The evolutionary trajectory of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has progressed through several distinct phases since its zoonotic emergence, transitioning from initial human adaptation to an era of rapid antigeni...
Congenital CMV and Hearing Loss-How Does it Happen and How to Prevent it [0.03%]
先天性巨细胞病毒感染与听力损失：发病机制及预防措施
Karen B Fowler
Karen B Fowler
Congenital cytomegalovirus (cCMV) is found worldwide and significantly contributes to permanent childhood hearing loss. CMV has been known to cause sensorineural hearing loss (SNHL) for more than half a century, and CMV-related hearing loss...
Beyond the Usual Suspects: Emerging Associations Between Epstein-Barr Virus Infection/Infectious Mononucleosis and Cancers [0.03%]
埃博拉病毒感染/传染性单核细胞增多症与癌症的新兴关联超越了惯常猜测
Marisa D Muckian,Graham S Taylor,John Diaz-Decaro et al.
Marisa D Muckian et al.
Epstein-Barr virus (EBV) is a ubiquitous herpesvirus and a causal factor for Burkitt Lymphoma (BL), Hodgkin Lymphoma (HL), gastric carcinoma (GC) and nasopharyngeal carcinoma (NPC). Whether EBV contributes to a wider spectrum of cancers rem...
De-Feng Li,Mei-Feng Yang,Ning-Ning Yue et al.
De-Feng Li et al.
Virus-like nanoparticles (VLPs) are naturally occurring polymeric nanomaterials formed by the self-assembly of one or more viral capsid proteins (CPs). VLPs have garnered significant attention in a wide range of nanotechnology-based diagnos...
Clinical Importance of the Newly Emerging Influenza A(H3N2) Subclade K as the Dominant Variant [0.03%]
新出现的甲型流感(AH3N2)亚支系K临床意义重大并已成为主要变异株
Erta Rajabi,Kousha Farhadi,Mohammadreza Salehi
Erta Rajabi
Global Vaccine Confidence at a Crossroads: Immunisation Coverage Declines, Misinformation, and the Future of Vaccine Policy [0.03%]
全球疫苗信任度面临十字路口：免疫接种覆盖率下降、错误信息以及疫苗政策的未来
Alfi Sophian,Normasari,Andhika Harumanto et al.
Alfi Sophian et al.
Vaccination remains one of the most effective public health interventions; however, recent global trends indicate a reversal in routine immunisation coverage alongside resurgent outbreaks of vaccine-preventable diseases. This review synthes...