Efficacy, Immune Response, and Safety of Dengue Vaccines in Adolescents: A Systematic Review [0.03%]
登革热疫苗在青少年中的疗效、免疫应答和安全性：系统性综述
Ramtin Naderian,Majid Eslami,Sajjad Ahmad et al.
Ramtin Naderian et al.
Both health and economic burdens of dengue virus (DENV), as an increasingly prevalent pathogen and global threat, exist in endemic regions. Vaccination is a key strategy in decreasing dengue morbidity and mortality. This systematic review a...
Arbovirus Infections and Epigenetic Mechanisms; a Potential Therapeutic Target [0.03%]
虫媒病毒感染与表观遗传机制；一个潜在的治疗靶点
Manhong Wang,Kexin Liu,Dan Guo et al.
Manhong Wang et al.
Arboviruses are a group of arthropod-borne viral pathogens that pose a significant threat to the public health system. The clinical manifestations associated with these viruses range from self-limiting infections to life-threatening disorde...
Sex-Based Differences in Cardiovascular Outcomes Associated With COVID-19: A Systematic Review and Meta-Analysis [0.03%]
与COVID-19相关的心血管结局的性别差异：系统评价和荟萃分析
Tareq M Abubasheer,Hanan M A Abubasheer,Ramez M Odat et al.
Tareq M Abubasheer et al.
COVID-19 has emerged as a global health crisis with significant consequences, not only for respiratory health but also for the cardiovascular system. This study aimed to investigate potential sex-based disparities in cardiovascular outcomes...
Monitoring Macrophage Polarization in Infectious Disease, Lesson From SARS-CoV-2 Infection [0.03%]
监控传染病中的巨噬细胞极化：从SARS-CoV-2感染中获得的启示
Soraya Mezouar,Jean-Louis Mege
Soraya Mezouar
The concept of macrophage polarization has been largely used in human diseases to define a typology of activation of myeloid cells reminiscent of lymphocyte functional subsets. In COVID-19, several studies have investigated myeloid compartm...
Neha Pandey,Sunit K Singh
Neha Pandey
Chandipura virus (CHPV) is a single-stranded negative-sense RNA virus of the family Rhabdoviridae. CHPV is transmitted mainly through infected sandflies. CHPV paediatric encephalitis reported in 2003-2004 in central and south-western parts ...
Joel Schwartz,Kristelle Capistrano,Heba Hussein et al.
Joel Schwartz et al.
SARS-CoV-2 is an oral pathogen that infects and replicates in mucosal and salivary epithelial cells, contributing to oral post-acute sequelae COVID-19 (PASC) and other oral and non-oral pathologies. While pre-existing inflammatory oral dise...
Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti-Alphavirus Therapies [0.03%]
Alphavirus nsP2：多功能的病毒复制调控因子及有潜力的抗Alphavirus治疗靶点
Sainan Wang,Suresh Mahalingam,Andres Merits
Sainan Wang
Alphaviruses are re-emerging vector-born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor ar...
Daniele Focosi,Francesca Colavita,Silvia Meschi et al.
Daniele Focosi et al.
In 2024, a novel recombinant of the Oropouche virus emerged as a potential threat. This virus has caused a significant outbreak in Brazil and Cuba, with imported cases subsequently reported in the USA and Europe. This review summarises the ...
Dengue Virus Life Cycle and Host Protein Interactions: Focus on RNA Binding Proteins and Therapeutic Advances [0.03%]
登革病毒生命周期和宿主蛋白互作：聚焦RNA结合蛋白及治疗进展
Anjali Singh,Riya Roy,Kinjal Singh et al.
Anjali Singh et al.
Dengue, a widespread arthropod-borne viral disease, remains endemic in more than 100 nations, affecting over 40% of the world's population, with millions of cases reported annually, and has a major burden on global public health systems. Th...
Emerging Nipah Virus With Pandemic Potential and High Mortality Rates: Is the Scientific Community Learning From Former Pandemics? [0.03%]
具有大流行潜力和高死亡率的新兴Nipah病毒：科学界从前一次大流行中吸取教训了吗？
Doris Klingelhöfer,Markus Braun,Christina A Naser et al.
Doris Klingelhöfer et al.
As Nipah virus (NiV) infection is characterised by a possible pandemic risk, being currently limited to a small but deadly belt, the attention of other countries is essential. It has often been pointed out that NiV is an under-researched vi...