Apoptotic and anti-Warburg effect of Morusin via ROS mediated inhibition of FOXM1/c-Myc signaling in prostate cancer cells [0.03%]
染料木素通过ROS介导的抑制FOXM1/c-Myc信号在前列腺癌细胞中诱导凋亡和抗瓦博格效应
Ja Il Koo,Deok Yong Sim,Hyo-Jung Lee et al.
Ja Il Koo et al.
Though Morusin is known to induce apoptotic, antiprolifertaive, and autophagic effects through several signaling pathways, the underlying molecular mechanisms of Morusin still remain unclear until now. To elucidate antitumor mechanism of Mo...
Therapeutic prospects of naturally occurring p38 MAPK inhibitors tanshinone IIA and pinocembrin for the treatment of SARS-CoV-2-induced CNS complications [0.03%]
天然p38 MAPK抑制剂丹参素和扁桃醇治疗SARS-CoV-2引起的中枢神经系统并发症的前景
Mehdi Valipour
Mehdi Valipour
P38 mitogen-activated protein kinase (p38 MAPK) signaling pathway is closely related to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) replication and hyperinflammatory responses in coronavirus disease 2019 (COVID-19). Therefo...
Magnolol alleviates pulmonary fibrosis inchronic obstructive pulmonary disease by targeting transient receptor potential vanilloid 4-ankyrin repeat domain [0.03%]
肉桂酰胺通过靶向瞬时受体电位香草酸4-锚蛋白重复域缓解慢性阻塞性肺疾病的肺纤维化
Lin Niu,Yu-Jie Lu,Xing-Wang Zu et al.
Lin Niu et al.
Transient receptor potential vanilloid 4 (TRPV4) plays a role in regulating pulmonary fibrosis (PF). While several TRPV4 antagonists including magnolol (MAG), have been discovered, the mechanism of action is not fully understood. This study...
Comparing the activity of propolis-loaded nanoparticles or hydroethanolic extract on cytokine production by peripheral blood mononuclear cells [0.03%]
载有蜂胶的纳米粒子或氢乙醇提取物对外周血单核细胞产生细胞因子的影响比较
Arthur A Sartori,Eliza de Oliveira Cardoso,Karina B Santiago et al.
Arthur A Sartori et al.
Sanguisorba officinalis L. promotes diabetic wound healing in rats through inflammation response mediated by macrophage [0.03%]
牻牛儿苗促进糖尿病大鼠伤口愈合的炎症反应及巨噬细胞介导机制研究
Jianying Song,Jing Zeng,Silin Zheng et al.
Jianying Song et al.
Sanguisorba officinalis L., a traditional Chinese medicine, is frequently used to treat burns and scalds. But even so, it is unknown whether S. officinalis L. can accelerate diabetic wounds (DW) healing. Here, to bridge the gap, we employed...
Garcinone E suppresses breast cancer growth and metastasis by modulating tumor-associated macrophages polarization via STAT6 signaling [0.03%]
姜黄素通过STAT6信号调节肿瘤相关巨噬细胞极化来抑制乳腺癌的生长和转移
Xin Nie,Li Fu,Yanfen Cheng et al.
Xin Nie et al.
Cancer metastasis remains the most common cause of death in breast cancer patients. Tumor-associated macrophages (TAMs) are a novel therapeutic target for the treatment of metastatic breast cancer. Despite the good anti-cancer activity of g...
Salidroside ameliorated the pulmonary inflammation induced by cigarette smoke via mitigating M1 macrophage polarization by JNK/c-Jun [0.03%]
番红花苷通过JNK/c-Jun途径改善香烟烟雾诱发的肺部炎症及M1型巨噬细胞极化作用研究
Haoshen Feng,Dan Zhang,Yan Yin et al.
Haoshen Feng et al.
Pulmonary inflammation induced by cigarette smoke (CS) promoted the development of chronic obstructive pulmonary disease (COPD), and macrophage polarization caused by CS modulated inflammatory response. Previous studies indicated that salid...
Honokiol inhibits epithelial-mesenchymal transition and hepatic fibrosis via activation of Ecadherin/GSK3β/JNK and inhibition of AKT/ERK/p38/β-catenin/TMPRSS4 signaling axis [0.03%]
肉桂酰亚胺通过激活E-钙粘蛋白/GSK3β/JNK并抑制AKT/ERK/p38/β-连环素/TMPRSS4信号轴诱导上皮间质转化及肝纤维化
Jae Hwa Seo,Hyo-Jung Lee,Deok Yong Sim et al.
Jae Hwa Seo et al.
Though Honokiol was known to have anti-inflammatory, antioxidant, anticancer, antithrombotic, anti-viral, metabolic, antithrombotic, and neurotrophic activities, the underlying mechanisms of Honokiol on epithelial-mesenchymal transition (EM...
Fucoidan derived from Sargassum pallidum alleviates metabolism disorders associated with improvement of cardiac injury and oxidative stress in diabetic mice [0.03%]
磺藻糖鼠李糖聚硫酸酯改善龙须菜对糖尿病小鼠心脏损伤及氧化应激的影响及其对代谢障碍的缓解作用
Zhiyong Lin,Fengwei Wang,Yawei Yan et al.
Zhiyong Lin et al.
Type 2 diabetes mellitus (T2DM) and its complications have become a serious global health epidemic. Cardiovascular complications have considered as a major cause of high mortality in diabetic patients. Fucoidans from brown algae have divers...
Correction to Quercetin ameliorates ROS generation, inflammation, mucus depletion, goblet disintegration, and tumor multiplicity in colon cancer: Probable role of APC, β-Catenin [0.03%]
檞皮素通过靶向APC、β-连环蛋白改善结肠癌小鼠的ROS生成、炎症反应及肿瘤发生和生长的研究及其意义的更正
Published Erratum
Phytotherapy research : PTR. 2023 Jul;37(7):3182-3188. DOI:10.1002/ptr.7805 2023