A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Study of Efficacy and Safety of Ashwagandha Root Extract Capsule on Skin and Hair Health in Healthy Adults [0.03%]
阿育吠陀Ashwagandha根提取物胶囊对健康成年人皮肤和头发健康的功效及安全性：一项前瞻性、随机的双盲安慰剂对照临床研究
Aditya Jillella,N Keerthi,J Venkateswar Reddy
Aditya Jillella
Hair loss and skin conditions have a detrimental influence on personality, health, and quality of life (QoL). Herbs from Ayurveda, such as ashwagandha having multimodal biological activities, are being researched as potential remedies for t...
Targeting the NLRP3 Inflammasome in Atherosclerosis: Advances in Anti-Inflammatory Therapies With Bioactive Natural Products [0.03%]
针对动脉粥样硬化中NLRP3炎性小体的治疗：活性天然产物抗炎疗法的研究进展
Haizhen Guo,Shule Qian,Yu Lu et al.
Haizhen Guo et al.
Atherosclerosis (AS) serves as the shared pathological substrate for cardiovascular and cerebrovascular diseases. The traditional passive-accumulation model centered on cholesterol no longer explains why lipid targets are met while clinical...
Unveiling the Therapeutic Potential of Flavones: A Review on Biological Activities and Mechanisms [0.03%]
黄酮类化合物的治疗潜力：生物学活性与机制综述
Elmehdi Fraj,Mohammed Merzouki,Chaymae Bourhou et al.
Elmehdi Fraj et al.
Flavones, or 2-phenylchromones, are a group of oxygenated heterocyclic compounds belonging to the family of flavonoids. Studying these secondary metabolites has regained interest due to their diverse pharmacological potential, including ant...
Farnesol Targets the GSTP1/MAPK Axis to Inhibit Trauma-Induced Tendon Heterotopic Ossification [0.03%]
法尼醇靶向GSTP1 / MAPK轴以抑制创伤引起的异位骨化
Xiao Deng,Tong Li,Guanzhi Li et al.
Xiao Deng et al.
Heterotopic ossification (HO) within tendons leads to debilitating tissue dysfunction, primarily arising from the abnormal osteogenic differentiation of tendon-derived stem cells (TDSCs). Despite its clinical prevalence, effective pharmacol...
Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A [0.03%]
黄芪甲苷通过靶向磷酸二酯酶9A抑制心脏重塑
Liqian Chen,Xinghong Zhou,Yanting You et al.
Liqian Chen et al.
Background and aim: New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)-protein kinase G (PKG) pathway on heart have been widely reported. Desp...
Morin: A Comprehensive Review of Its Sources, Nutraceutical Prospects, Chemistry, and Pharmacological Insights [0.03%]
morin：药用资源、营养功效、化学成分及药理作用的全面综述
Shekhar Kumar,Akanksha Raghuvanshi,Aman Kumar et al.
Shekhar Kumar et al.
Nature has continuously offered an abundance of essential nutrients that sustain the life of various organisms on Earth. Among the plethora of gifts provided by nature, plants have emerged as the most valuable ones, not just because they pr...
Exploring Linalool-Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition [0.03%]
探究薄荷醇植物疗法在阿尔茨海默病兴奋/抑制失衡中的应用：一篇关于薰衣草和大麻对睡眠、癫痫发作和认知治疗效果的综述性文章
Ilaria Piccialli,Giovanni Roviello,Giorgia Magliocca et al.
Ilaria Piccialli et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and behavioral disturbances. While its pathogenesis is complex, increasing evidence supports the role of an imbalanc...
Punicalagin Promotes Peripheral Nerve Repair by Enhancing Mitophagy via the TLR4/MAPK Signaling Pathway and Facilitating Angiogenesis [0.03%]
芸香素通过TLR4/MAPK信号通路促进线粒体自噬及血管生成从而促进外周神经再生修复作用研究
Anhao Guo,Ke Wang,Jinghao Liang et al.
Anhao Guo et al.
Peripheral nerve injury (PNI) often leads to functional impairment, and current therapeutic options are limited. Punicalagin (PUN), a polyphenolic compound derived from Punica granatum, exhibits antioxidant and anti-inflammatory properties....
Ashwagandha (Withania somnifera) Root Extract Improves General Health in Elderly Men and Women: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study [0.03%]
阿育吠陀草药仙露兰根提取物改善老年人健康的功效和安全性研究：一项前瞻性、随机、双盲、安慰剂对照的疗效和安全性的研究
R Honnutagi,Anand Ingale,Akram Naikawdi
R Honnutagi
Ashwagandha (Withania somnifera), an adaptogen, is widely used in traditional Indian medicine for its health benefits in elderly people with functional limitations and physical disabilities. This double-blind, randomized, placebo-controlled...
Periplogenin Suppresses Hepatocarcinogenesis by Inducing Cellular Senescence via the Activating FOXO1/P53 Signaling Pathway [0.03%]
通过激活FOXO1/P53信号通路诱导细胞衰老从而抑制肝癌的发生发展：黄花蒿二萜类化合物千里光宁的化学诱导抗肿瘤作用研究
Peizhen Wang,Jianyu Zhu,Wen Li et al.
Peizhen Wang et al.
Hepatocellular carcinoma (HCC) remains a challenging malignancy with limited therapeutic options. This study aimed to investigate the antitumor effects of periplogenin, a bioactive compound derived from Cortex Periplocae, and to explore its...