Icariin alleviates ferroptosis-related atherosclerosis by promoting autophagy in xo-LDL-induced vascular endothelial cell injury and atherosclerotic mice [0.03%]
淫羊藿苷通过促进XO-LDL诱导的血管内皮细胞自噬减轻与铁死亡相关的动脉粥样硬化
Xindong Wang,Meng Zhang,Chenhan Mao et al.
Xindong Wang et al.
Vascular endothelial cells (VECs) are located between the blood plasma and the vascular tissue, and the ferroptosis (iron-dependent programmed cell death) of VECs can lead to a range of cardiovascular diseases. Icariin is the main active in...
Antihypertensive effects of Nigella sativa supplementation: An updated systematic review and meta-analysis of randomized controlled trials [0.03%]
胡椒薄荷补充对高血压的影响：随机对照试验的系统综述和meta分析更新版本
Zeynab Kavyani,Vali Musazadeh,Ehsan Safaei et al.
Zeynab Kavyani et al.
Clinical studies have suggested that Nigella Sativa (N. sativa) supplementation may effectively reduce blood pressure, but the findings are controversial. Therefore, this study aimed to examine the effects of N. sativa on blood pressure in ...
Salvianolic acid A diminishes LDHA-driven aerobic glycolysis to restrain myofibroblasts activation and cardiac fibrosis via blocking Akt/GSK-3β/HIF-1α axis [0.03%]
垂体后叶素联合白术苷通过抑制Akt/GSK-3β/HIF-1α轴减少成纤维细胞向肌成纤维细胞转化及抗心衰作用及其机制研究
Renaguli Hailiwu,Hao Zeng,Meiling Zhan et al.
Renaguli Hailiwu et al.
Myofibroblasts activation intensively contributes to cardiac fibrosis with undefined mechanism. Salvianolic acid A (SAA) is a phenolic component derived from Salvia miltiorrhiza with antifibrotic potency. This study aimed to interrogate the...
Cordycepin: A review of strategies to improve the bioavailability and efficacy [0.03%]
虫草素研究进展：提高生物利用度和药效的策略分析
Min Chen,Jiahao Luo,Wenming Jiang et al.
Min Chen et al.
Cordycepin is a bioactive compound extracted from Cordyceps militaris. As a natural antibiotic, cordycepin has a wide variety of pharmacological effects. Unfortunately, this highly effective natural antibiotic is proved to undergo rapid dea...
Anti-inflammatory effect of dictamnine on allergic rhinitis via suppression of the LYN kinase-mediated molecular signaling pathway during mast cell activation [0.03%]
Dictamnine通过抑制大鼠肥大细胞活化过程中LYN激酶介导的分子信号转导通路对过敏性鼻炎的抗炎作用研究
Rui Liu,Yonghui Zhang,Yuejin Wang et al.
Rui Liu et al.
Mast cells (MCs) are important therapeutic targets for allergic diseases. High-affinity immunoglobulin E (IgE) Fc receptors (FcεRI) trigger abnormal activation of MCs. Allergic rhinitis (AR) is an IgE-mediated antigen inhalation reaction t...
Dual targeting of wild-type p53 and gut microbiota by Magnolol represses key metabolic process and kills CRC cells [0.03%]
Magnolol通过双重靶向野生型p53和肠道微生物抑制关键代谢过程并杀死结直肠癌细胞
Haixia Ji,Ou Qiao,Yi Zhang et al.
Haixia Ji et al.
Cancer cells consume considerable glucose quantities and majorly employ glycolysis for ATP generation. This metabolic signature (the Warburg effect) allows cancer cells to channel glucose to biosynthesis to support and maintain their dramat...
Correction to "Quercetin alleviates ethanol-induced hepatic steatosis in L02 cells by activating TFEB translocation to compensate for inadequate autophagy" [0.03%]
槲皮素通过激活TFEB转位来补偿自噬不足以缓解乙醇诱导的L02肝细胞脂肪变性的修正案
Published Erratum
Phytotherapy research : PTR. 2023 Sep;37(9):4298. DOI:10.1002/ptr.7911 2023
Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter [0.03%]
桔梗皂苷通过激活法尼醇X受体和胆汁酸转运蛋白调节小鼠肝和回肠胆汁酸排泄
YuKun Wang,Jing Li,Li Wu et al.
YuKun Wang et al.
Radix Bupleuri exerts effective hepatoprotective and cholagogic effects through its Saikosaponins (SSs) component. Therefore, we attempted to determine the mechanism of saikosaponins used to promote bile excretion by studying their effects ...
Effect of sesame (Sesamum indicum L.) consumption on glycemic control in patients with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials [0.03%]
食用芝麻对2型糖尿病患者血糖控制的影响：随机对照试验的系统评价和荟萃分析
Andrés Alexis Ramírez-Coronel,Khetam Abdalsada Ali Alhilali,Yasmin Basheer Ahmed et al.
Andrés Alexis Ramírez-Coronel et al.
Conflicting evidence exists on the effect of sesame consumption on glucose metabolism in patients with type 2 diabetes (T2D). Therefore, this meta-analysis focuses on the relationship between sesame (Sesamum indicum L.) intervention and gly...
The effect of propolis supplementation in improving antioxidant status: A systematic review and meta-analysis of controlled clinical trials [0.03%]
巴西绿蜂胶改善抗氧化状态的补充效果：系统评价和荟萃分析
Hamideh Nazari-Bonab,Parmida Jamilian,Nima Radkhah et al.
Hamideh Nazari-Bonab et al.
The present study aimed to assess the effect of propolis supplementation on oxidative status, a key contributor to the etiology of many chronic diseases. A systematic search of multiple databases, including Web of Science, SCOPUS, Embase, P...