The Allium cepa Derived Compound Propyl Propane Thiosulfonate (PTSO) Improves Tumorigenesis Due to Its Immunomodulatory Effect: A Preclinical Study [0.03%]
大蒜衍生的化合物丙基三硫改善肿瘤的发生由于其免疫调节作用：一项临床前研究
María Jesús Rodríguez-Sojo,Laura Hidalgo-García,Jose Alberto Molina-Tijeras et al.
María Jesús Rodríguez-Sojo et al.
Allium-derived organosulfur compounds offer significant health benefits. Specifically, PTSO, an organosulfur compound extracted from Allium cepa, has demonstrated immunomodulatory and prebiotic properties. However, its effects on tumorigene...
Dietary Polyphenols and Their Impact on Nrf2 Pathway in Non-Alcoholic Fatty Liver Disease: A Review of In Vitro and In Vivo Studies [0.03%]
膳食多酚及其对非酒精性脂肪肝病中Nrf2通路的影响：体内外研究综述
Ali Akbar Soleimani,Behnam Omidi Sarajar,Masoumeh Aliabadi et al.
Ali Akbar Soleimani et al.
Oxidative stress is a critical event in the development of metabolic disorders, including non-alcoholic fatty liver disease (NAFLD), diabetes, and cardiovascular diseases. Recent research has increasingly focused on the potential benefits o...
Green Tea Consumption Potentiates Paclitaxel Cytotoxic Efficacy in Vitro and Antitumor Efficacy in Vivo: A Pharmacodynamic and Pharmacokinetic Study [0.03%]
体外和体内药动学及药效学研究显示绿茶消耗可增强帕利昔露安的细胞毒性和抗肿瘤作用
Yubo Zhang,Na Du,Yingqian Ci et al.
Yubo Zhang et al.
Green tea, a commonly consumed beverage worldwide, is extensively used as dietary supplements for cancer prevention. However, the interaction between green tea and paclitaxel is still unknown. This study aimed to systematically investigate ...
Paeoniflorin Ameliorates Liver Fibrosis by Inhibiting HIF-1α-Mediated Mitophagy in Hepatic Stellate Cells [0.03%]
芍药苷通过抑制肝星状细胞中HIF-1α介导的线粒体自噬来改善肝纤维化
Chunyu He,Yang Liu,Mengchen Qin et al.
Chunyu He et al.
Paeoniflorin (PF) has exhibited significant anti-hepatic fibrosis potential, yet its precise pharmacological mechanisms and molecular targets remain to be fully elucidated. This study aims to investigate the role of PF in modulating HIF-1α...
Phytochemicals in Inflammatory Bowel Disease: Targeting Oxidative Stress for Improved Gut Health [0.03%]
植物化学物质在炎症性肠病中的作用：靶向氧化应激以改善肠道健康
Junyan Gao,Zixuan He,Fan Wang et al.
Junyan Gao et al.
Inflammatory bowel disease (IBD) is a group of chronic gastrointestinal inflammatory disorders, primarily including ulcerative colitis (UC) and Crohn's disease (CD). Reactive oxygen species (ROS) play a pivotal role in the pathogenesis of t...
Phytochemicals in MASLD: A Focused Review of Gut Microbiome-Linked Mechanisms [0.03%]
与肠道微生物群相关的MASLD植物化学物质机制的综述研究
Jeong In Seo,Su Min Kim,Hye Hyun Yoo
Jeong In Seo
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver met...
Exploring the Therapeutic Potential of Phytochemicals in Modulating Synaptic Plasticity and Neuroinflammation in Depression [0.03%]
探究植物化学物质在调节抑郁症中突触可塑性和神经炎症方面的治疗潜力
Patel Parthkumar,Prasanta Kumar Nayak
Patel Parthkumar
Depression is a debilitating psychiatric disorder characterized by symptoms such as anhedonia (loss of pleasure), anxiety, persistent sadness, and suicidal ideation. In the past few years, the prevalence rate of depression has been continuo...
Activation of MTCH2 by Momordin Ic Prevents Colitis and Colitis-Associated Colorectal Cancer Through Rescuing the Mitochondrial Dysfunction of Macrophage [0.03%]
冰片宁Ic通过激活MTCH2防治肠炎及其相关结直肠癌的机制研究：重塑巨噬细胞线粒体功能
Fang Xianjun,Zhai Chi,Yu Haixia et al.
Fang Xianjun et al.
Inflammation is associated with various cancers, including colorectal cancer. Momordin Ic (MIc) has anti-tumor and anti-inflammatory properties, but its effects on colitis-associated colorectal cancer (CAC) are not well understood. This stu...
Synergistic Effects of Exercise and Dietary Polyphenols on Cognitive Function and Neuroprotection in Aging: A Focus on Spatial Learning and Memory [0.03%]
运动和饮食多酚对衰老认知功能和神经保护的协同作用：以空间学习和记忆为重点
Rui Cheng,Xuejing Yang,Haiyang Su et al.
Rui Cheng et al.
This comprehensive review examines the synergistic effects of physical exercise and polyphenolic compounds, such as flavonoids, curcumin, and resveratrol, on spatial learning and memory. The interplay between these interventions highlights ...
Exploring Terpenoids as Dual-Action Agents in Diabetes and Cancer: A Review of Their Anti-Hyperglycemic, Anti-Glycolytic Actions, and Combination Therapy Potential [0.03%]
萜类化合物作为糖尿病和癌症的双效作用剂的研究：其抗高血糖、抗糖酵解作用及联合治疗潜力的综述
Siti Nur Hasyila Muhammad,Tuan Salwani Tuan Ismail,Agustine Nengsih Fauzi
Siti Nur Hasyila Muhammad
Cancer and diabetes represent a dual health burden linked by shared metabolic disturbances, particularly hyperglycemia and glycolytic reprogramming. This metabolic overlap highlights the need for agents capable of modulating both conditions...