Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies-A Systematic Review [0.03%]
鼻用治疗中黄酮类化合物的生物活性、递送挑战及制剂策略系统评价研究
Jeniffer Viviana Ramirez Hernández,Sara Elis Bianchi,Flávia Nathiely Silveira Fachel et al.
Jeniffer Viviana Ramirez Hernández et al.
Flavonoids represent a significant group of secondary metabolites. They have gained significant attention in the field of health due to their wide range of chemical structures and their diverse biological activities. These compounds have be...
Atractylenolide I Blocks Lung Metastasis of Triple-Negative Breast Cancer by Inhibiting SPP1-Mediated Extracellular Matrix Signaling Pathway [0.03%]
苍术素I通过抑制SPP1介导的细胞外基质信号通路阻断三阴性乳腺癌肺转移
Qingling Wang,Jiaxin Wang,Ruiwen Yang et al.
Qingling Wang et al.
Atractylodes macrocephala Koidz. has long been used for invigorating Qi and traditionally prescribed for cancer treatment by Chinese medicine practitioners. Atractylenolide I (ATI) is a major active component in A. macrocephala and has inhi...
Swietenine Enhances Autophagy to Improve Renal Fibrosis via AMPK/mTOR/ULK1 Signaling Pathway in Diabetic Nephropathy [0.03%]
斯蒂维因通过AMPK/mTOR/ULK1信号途径改善糖尿病肾病中肾纤维化促进自噬作用
Jingyu Duan,Feilong Pei,Cuicui Gu et al.
Jingyu Duan et al.
Diabetic nephropathy (DN) is a major complication of diabetes. Swietenine (Swi), a natural compound derived from the fruit of Swietenia macrophylla, has shown beneficial effects in alleviating diabetic complications. However, its underlying...
Yoganishalini Sagadevan,Reyhaneh Farghadani,Ammu K Radhakrishnan
Yoganishalini Sagadevan
Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple-negative...
The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum) [0.03%]
一种从石榴(Punica granatum)中获得的废弃物副产品的作用效果研究
Jessica Maiuolo,Valeria Mazza,Rosamaria Caminiti et al.
Jessica Maiuolo et al.
Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals a...
Increasing Dietary Quercetin Intake Reduces Stroke Risk and Improve Long-Term Survival in Chronic Kidney Disease Patients [0.03%]
增加饮食中的芸香苷摄入量可降低慢性肾脏病患者的卒中风险并改善长期生存率
Junqi Liao,Zhiquan Tang,Yechen Lu et al.
Junqi Liao et al.
Quercetin has anti-inflammatory properties. This study aims to explore the association between dietary quercetin intake, stroke risk, and long-term survival in chronic kidney disease (CKD) patients. The analysis included 2001 CKD participan...
Columbianadin Ameliorates Bleomycin-Induced Pulmonary Fibrosis by Inhibiting Cellular Senescence via the AMPK-Sirt1/3 Signaling Pathway [0.03%]
雷公藤红素通过AMPK-Sirt1/3信号通路抑制细胞衰老从而改善博来霉素诱导的肺纤维化
Zeng Qian,Luo Yu-Yang,Liao Min-Lin et al.
Zeng Qian et al.
Idiopathic pulmonary fibrosis is a chronic, progressive disease in older adults with unclear pathogenesis and a lack of effective drugs. Columbianadin, a natural coumarin analog isolated from Angelicae pubescentis Radix, has a wide range of...
Resveratrol Alleviates Inflammation in Polycystic Ovary Syndrome by Inhibiting Absent in Melanoma 2 Expression [0.03%]
白藜蘊素通过抑制Absent in Melanoma 2表达缓解多囊卵巢综合征炎症反应
Qianjie Zhang,Hui Li,Yicen Meng et al.
Qianjie Zhang et al.
Since chronic inflammation is a typical feature of polycystic ovary syndrome (PCOS), both clinical and experimental studies have demonstrated that resveratrol (RES) can effectively alleviate it. However, the underlying mechanism remains unc...
Unlocking the Therapeutic Potential of Ganoderma lucidum: From Bioactive Compounds to Clinical Translation [0.03%]
灵芝（Linxihui）的治疗潜力：从生物活性化合物到临床转化
Gadallah Mohamed,Zhixin Sun,Lifan Yu et al.
Gadallah Mohamed et al.
Ganoderma lucidum, a revered medicinal mushroom with a rich history in traditional East Asian medicine, has garnered significant scientific attention for its diverse pharmacological properties. This comprehensive review synthesises recent a...
Glucoerucin, Glucosinolate From Brassicaceae Vegetables, Improves the Metabolic Profile in a Murine Model of Diet-Induced Obesity [0.03%]
球根甘蓝芸苔属蔬菜中的芥子糖改善饮食诱导的肥胖小鼠模型代谢指标
Lorenzo Flori,Jacopo Spezzini,Giada Benedetti et al.
Lorenzo Flori et al.
Obesity is a main cause of morbidity worldwide, and its incidence has incredibly grown in recent years, leading to an increased risk for comorbidities, including cardiovascular and metabolic diseases. Timely intervention is essential and na...