Phytochemical Diversity and Evolving Strategies for the Quality Evaluation of Agarwood [0.03%]
沉香的植物化学多样性及其质量评价策略的新进展
Yanqiao Xie,Shengqi Huang,Yingmin Zhang et al.
Yanqiao Xie et al.
Background: Agarwood, a valuable resin-infused wood derived primarily from Aquilaria species (Thymelaeaceae), is widely used in traditional medicine, incense, perfumery, and healthcare products. Its growing scarcity, alon...
Hyperspectral Camera Imaging Tandem With HPLC-UV-ELSD Determination and Cell Bioassay for Geographical Discrimination and Quality Consistency Evaluation of Anoectochilus roxburghii [0.03%]
基于高光谱成像与高效液相色谱-紫外-蒸发光散射检测及细胞活性筛选的石斛原植物道地性与品质一致性评价
Haixia Xu,Qiuya Zhou,Qiluo Ni et al.
Haixia Xu et al.
Introduction: Anoectochilus roxburghii (AR) is a prized medicinal herb valued for its hepatoprotective effects. Its quality varies depending on geographical origin. The primary bioactive constituents include rutin, querce...
Advances in Exosome-Based Therapy for Cardiovascular Disease: Traditional Chinese Medicine Offering New Avenues for Exosome Functionalization [0.03%]
外泌体心血管病治疗研究进展：中医药助力外泌体功能化改造新途径
Yi Chen,Xiaoyu Sun,Yingbo Ouyang et al.
Yi Chen et al.
Background: Cardiovascular diseases (CVDs) remain a leading cause of global mortality and impose a substantial health and economic burden worldwide. Exosomes, as promising endogenous nanocarriers, have emerged as a powerf...
Plant-Derived Extracellular Vesicles (PDEVs): A Natural Nanoplatform Reshaping the Therapeutic Potential of Medicinal and Edible Plants [0.03%]
植物衍生的细胞外囊泡(PDEVs)：一种重塑药用和食用植物治疗潜力的天然纳米平台
Hongzhe Shen,Yanzhi Xiong,Mengjia Xu et al.
Hongzhe Shen et al.
Background: Medicinal and edible plant-derived compounds have held an important position in human history due to their therapeutic effects. However, their therapeutic potential is limited by their inherent poor stability,...
The Binding Ability of Aloe-Emodin to Free l-Cysteine on Hepatic Protein-Induced Hepatocyte Toxicity [0.03%]
大黄素与游离l半胱氨酸结合对肝蛋白诱导的肝细胞毒性的作用能力研究
Lingwen Dong,Yanan Liu,Lingge Shi et al.
Lingwen Dong et al.
Introduction: Aloe-emodin (AE), as an anthraquinone active component in traditional Chinese medicine, exhibits multiple pharmacological activities, yet its mechanism of hepatotoxicity remains unclear. The purpose of this ...
Antifibrotic Effects of Yi-Qi-Jian-Pi-Xiao-Yu Formula in Kidney via HIF1A-Driven M1 Macrophage Polarization [0.03%]
益气健脾消瘀方通过HIF1A驱动的M1型巨噬细胞极化抗纤维化作用及机制研究
Keda Lu,Liqing Ye,Wenze Jiang et al.
Keda Lu et al.
Background: A traditional Chinese medicine Yi-Qi-Jian-Pi-Xiao-Yu (YQJPXY) formula can potentially ameliorate chronic kidney disease (CKD), but its effect on renal fibrosis (RF), a prevalent pathological feature of CKD, re...
Recent Advances on the Chemical Compositions, Biological Activities, and Applications of Ziziphi Spinosae Semen: From Traditional Treasures to Modern Medical Stars [0.03%]
燕枣仁化学成分、生物活性及应用研究进展：从传统中药到现代药物明星分子
Yuchen Tang,Shukui Shang,Xue Runhua et al.
Yuchen Tang et al.
Introduction: As sleep disorders and mental stress become increasingly prevalent, public demand for functional foods and health products that improve sleep quality and alleviate insomnia continue to rise. Accordingly, it ...
Configurational Isomer Differentiation Between 20(S)- and 20(R)-Ginsenosides in Red Ginseng via Applying [CuII(l-Phe)2-H]+ to Post-Column Infusion LC-MS/MS [0.03%]
利用[CuII（l-Phe）2-H] +后柱输注LC-MS / MS区分红参中的20（S）-和20（R）-人参皂苷构型异构体
Maodong Wang,Hangyun He,Xingcheng Gong et al.
Maodong Wang et al.
Introduction: 20(R)-ginsenosides are formed by Walden inversion during ginseng processing and usually exhibit almost identical MS/MS behaviors, yet display distinct pharmacological activities compared with 20(S)-configura...
Integrating 3D Chromatography With Orbitrap Mass Spectrometry to Profile the Chemical Constituents in JTTZ Formula and Investigate Plasma Pharmacokinetic Changes in Obese Rats [0.03%]
三维色谱与轨道阱质谱联用分析加味金刚藤汤化学成分并探讨其对肥胖小鼠的药代动力学影响
Linfeng Zhou,Nanqi Hou,Tong Hou et al.
Linfeng Zhou et al.
Introduction: Chemical profiling and exposure of multicomponent Chinese medicine formula (CMF) are essential for understanding the multitarget treatment mechanism, as they consist of bioactive substances with varying pola...
Rapid Identification of the Quality of Eucommiae Cortex During the Whole Process of Salt Processing Based on Chromaticity and Near-Infrared Spectroscopy [0.03%]
基于色差和近红外光谱快速识别盐杜仲全过程质量等级研究
Keer Fang,Rui Tang,Hangsha Wu et al.
Keer Fang et al.
Background: As one of the traditional Chinese medicines, Eucommiae Cortex (EC) was often prepared with salt in the clinic to enhance its efficacy. However, its processing degree had always been judged by "experience," and...