Age- and Sex-Related Trends in Psychotropic Prescribing Among Youths in Denmark and the United States: 2010-2020 [0.03%]
丹麦和美国2010年至2020年青少年人群心境稳定剂及精神兴奋药物使用的年龄及性别差异研究趋势
Phuong Tran,Lotte Rasmussen,Alejandro Amill-Rosario et al.
Phuong Tran et al.
Objectives: To compare age- and sex-specific trends of psychotropic prescribing between Danish and US 3-17-year-old youths. Methods: A ...
Comparative Study
Pharmacoepidemiology and drug safety. 2025 Nov;34(11):e70256. DOI:10.1002/pds.70256 2025
EpiCore-A Common Data Model for Pharmacoepidemiological Studies in Denmark, Norway, and Sweden [0.03%]
EpiCore-丹麦、挪威和瑞典药物流行病学研究的常用数据模型
Peter Bjødstrup Jensen,Jacob H Andersen,Martin Thomsen Ernst et al.
Peter Bjødstrup Jensen et al.
Purpose: The use of common data models (CDMs) is increasing; however, the complexity of many CDM frameworks constitutes a barrier for their use. For many local and collaborative use cases, simpler CDMs can suffice. Here, ...
Perinatal Outcomes After the Use of Kampo Medicines Containing Ephedra During Pregnancy [0.03%]
含麻黄汉药在孕期使用后的围产期结局
Aoi Noda,Ryutaro Arita,Taku Obara et al.
Aoi Noda et al.
Purpose: Japanese traditional (Kampo) medicines containing ephedra are used to relieve symptoms of the common cold during pregnancy. The risks associated with perinatal outcomes, however, remain unclear. Thus, we evaluate...
Causal Forests Versus Inverse Probability of Treatment Weighting to Adjust for Cluster-Level Confounding: A Parametric and Plasmode Simulation Study Based on US Hospital Electronic Health Record Data [0.03%]
因果森林与逆概率治疗加权调整集群水平混淆的对比：基于美国医院电子健康记录数据的参数和模式模拟研究
Mike Du,Stephen Johnston,Paul M Coplan et al.
Mike Du et al.
Background: Rapid innovation and new regulations increase the need for post-marketing surveillance of implantable devices. However, complex multi-level confounding related to patient-level and surgeon or hospital covariat...
Comparative Study
Pharmacoepidemiology and drug safety. 2025 Nov;34(11):e70257. DOI:10.1002/pds.70257 2025
Seo Young Park,Jaeil Ahn,Jae Hoon Lee et al.
Seo Young Park et al.
Background: Inverse probability weighting (IPW) is a widely used method to estimate the causal effect of treatment from observational data. However, it can be unstable when extreme propensity score (PS) values lead to ver...
Comparative Risk for Neuropsychiatric Events in Leukotriene Receptor Antagonist vs. Inhaled Corticosteroid in Children With Asthma: A Nationwide Observational Study With a Complementary Analysis Using Natural Language Processing [0.03%]
白三烯受体拮抗剂与吸入性皮质类固醇治疗儿童哮喘的神经精神不良事件比较：一项全国性队列研究及自然语言处理补充分析
Subin Kim,Chang Hoon Han,Junhyuk Chang et al.
Subin Kim et al.
Purpose: Leukotriene receptor antagonists (LTRAs) are widely prescribed as controller medications for pediatric asthma. However, there have been increasing concerns about potential neuropsychiatric adverse reactions assoc...
Observational Study
Pharmacoepidemiology and drug safety. 2025 Nov;34(11):e70254. DOI:10.1002/pds.70254 2025
Effectiveness and Safety of Reduced and Standard Initial Doses of Regorafenib in Patients With Metastatic Colorectal Cancer: A Multicenter Retrospective Study in Taiwan [0.03%]
减剂量和常规起始剂量瑞戈非尼治疗转移性结直肠癌患者的疗效与安全性：台湾多中心回顾性研究
Yu-Hsuan Kuo,Chun-Nan Kuo,Chia-Lun Chang et al.
Yu-Hsuan Kuo et al.
Purpose: This study aims to compare the effectiveness and safety of standard and reduced initial doses of regorafenib in patients with metastatic colorectal cancer (mCRC). ...
Observational Study
Pharmacoepidemiology and drug safety. 2025 Nov;34(11):e70221. DOI:10.1002/pds.70221 2025
Research Sprints: An Intensive 1-Week Approach to Training Collaborative Work in Pharmacoepidemiologic Research [0.03%]
研究冲刺：一种密集的为期一周的培训方法，用于培养药物流行病学研究中的协作工作能力
Mette Reilev,Jesper Hallas;Pharmacoepidemiology Group at Clinical Pharmacology, Pharmacy and Environmental Medicine et al.
Mette Reilev et al.
Assessing the Impact of the COVID-19 Pandemic on Relative Incidence Rates in United States Claims Data [0.03%]
评估COVID-19大流行对美国索赔数据中相对发病率的影响
Julie Barberio,Kexin Zhu,Venkatesh Harikrishnan et al.
Julie Barberio et al.
Background: Differential COVID-19-pandemic-related changes to healthcare-seeking behavior across patient groups could contribute to biased estimates of disease incidence. ...
Clozapine-Associated Neutropenia Prevalence in a Large, Integrated Healthcare System [0.03%]
在一个大型综合医疗系统中氯氮平相关性粒细胞缺乏的流行率
Jill L Nofziger,Andrea H Kline-Simon,Leah M Arnbrecht et al.
Jill L Nofziger et al.
Purpose: Clozapine, a highly effective antipsychotic medication, is associated with rare but potentially life-threatening neutropenia. In February 2025, the US Food and Drug Administration (FDA) eliminated its clozapine R...