The Challenges for Pharmacoepidemiologists Identifying Migraine in Electronic Healthcare Data Sources: A Systematic Literature Review [0.03%]
药物流行病学工作者在电子健康数据中识别偏头痛的挑战：系统文献回顾
Joan Forns,Alicia Abellan,Nuria Riera-Guàrdia et al.
Joan Forns et al.
Purpose: Ascertaining migraine in electronic healthcare data is challenging because of likely diagnosis underrecording and treatment with over-the-counter analgesics, which cannot be used as disease proxies. Algorithm-ide...
Trends in Medication Use Among Young Adults and the Covid-19 Pandemic Effect [0.03%]
年轻人的药物使用趋势及新冠疫情的影响
Meital Zur,Avishai M Tsur,Limor Friedensohn et al.
Meital Zur et al.
Introduction: The COVID-19 pandemic caused unprecedented disruptions in healthcare delivery, and changes in medication utilization patterns. While previous studies examined specific therapeutic classes or populations, the...
All Lines Is the Right Approach: Selecting Patient Lines of Therapy for an External Comparator Arm [0.03%]
千线汇聚方得始终——选择外部对照组的治疗线数
Daniel Backenroth,Laura Hester,Stijn Vansteelandt
Daniel Backenroth
Purpose: To identify the best method for selecting index dates when constructing external comparator arms (ECAs) from real-world data for comparison with single-arm trials (SATs). ...
Applying High-Dimensional Propensity Scores in a Study of Inhaled Corticosteroids and COVID-19 Outcomes [0.03%]
高维倾向评分在吸入皮质类固醇和新冠肺炎预后研究中的应用
Marleen Bokern,John Tazare,Christopher T Rentsch et al.
Marleen Bokern et al.
Background: In pharmacoepidemiologic studies of COVID-19, there were concerns about bias from residual confounding. We investigated the effects of inhaled corticosteroids (ICS) on COVID-19 outcomes, applying high-dimensio...
Dimensionality Reduction Techniques for Improving Propensity Score Specification: An Application to a Cohort Study Using Claims Data [0.03%]
用于改进倾向得分规范的降维技术：基于理赔数据队列研究的一项应用
Sudhir Venkatesan,Jonatan Nåtman,Eva Lesén et al.
Sudhir Venkatesan et al.
Purpose: To apply various dimensionality reduction techniques for propensity score (PS) estimation in high-dimensional data and evaluate their performance against more conventional approaches in achieving covariate balanc...
Comparison of Linked EHR-Pharmacy Data and Administrative Claims Data: Medication Fills During Pregnancy [0.03%]
比较链接的EHR-药房数据和管理索赔数据：怀孕期间的药物填充情况
Gregory P Jansen,Gabriela Vazquez-Benitez,Kirsten Ehresmann et al.
Gregory P Jansen et al.
Purpose: Electronic health records (EHR) offer clinical details not available in claims data, which are typically used for studies of medications during pregnancy. Historically, medication prescriptions rather than fills ...
Comparative Study
Pharmacoepidemiology and drug safety. 2025 Dec;34(12):e70271. DOI:10.1002/pds.70271 2025
Titel: Risk of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Among Patients Treated With Immune Checkpoint Inhibitors Compared to Other Antineoplastic Medications: A Nationwide Study [0.03%]
免疫检查点抑制剂与其它抗肿瘤药物治疗患者中史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症风险的比较：一项全国性研究
Ida M Heerfordt,Magnus Middelboe,Christian Kjer Heerfordt et al.
Ida M Heerfordt et al.
Purpose: This study aimed to assess the risk of Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) among patients treated with immune checkpoint inhibitors (ICIs), compared to those receiving molecularly ta...
Comparative Study
Pharmacoepidemiology and drug safety. 2025 Nov;34(11):e70272. DOI:10.1002/pds.70272 2025
Epidemiological Profile of Exogenous Intoxications by Self-Medication in Brazil: A Decade of Trends and the Impact of the COVID-19 [0.03%]
巴西自我药疗外源性中毒的流行病学特征：十年趋势及COVID-19的影响
Lucas Borges Pereira,Júlia Casanova Durante,Leonardo Régis Leira Pereira et al.
Lucas Borges Pereira et al.
Purpose: Self-medication carries the potential for significant adverse events when practiced irresponsibly. The indiscriminate use of medicines notably intensified during the COVID-19 pandemic. This study aimed to investi...
Increasing Prevalence of Long-Term Antidepressant Use in Australia: A Retrospective Observational Study [0.03%]
澳大利亚长期抗抑郁药使用率增加：一项回顾性观察研究
R A D L M K Ranwala,Elizabeth E Roughead,Jean-Pierre Calabretto et al.
R A D L M K Ranwala et al.
Background: Long-term antidepressant use may reduce the risk-benefit profile due to the increased likelihood of withdrawal symptoms and higher incidence of side effects. This epidemiological study investigates historical ...
Observational Study
Pharmacoepidemiology and drug safety. 2025 Nov;34(11):e70267. DOI:10.1002/pds.70267 2025
Utilization of Oral Contraceptives and Hormone Therapy for Menopause Among Female Individuals With Migraine With Aura: A Descriptive Study [0.03%]
一项描述性研究：偏头痛伴 aura 的女性人群中口服避孕药和激素治疗的使用情况
Liza R Gibbs,Matthew P Fox,Hugo J Aparicio et al.
Liza R Gibbs et al.
Purpose: Combined oral contraceptives (COCs) are contraindicated in migraine with aura due to stroke risk, and some hormone therapy for menopause guidelines recommend caution in this population. However, this guidance is ...