Association Between First-Trimester Medication Exposure in Pregnancy and Congenital Anomalies: A Scoping Review of Cohorts, Exposure, Trimester and Congenital Anomaly Definitions [0.03%]
妊娠早期药物暴露与先天性畸形相关性的系统综述：关于队列、暴露因素、孕期及先天性疾病定义的一次范围回顾
Stephanie Tan,Ebony Quintrell,Shannon Morgan et al.
Stephanie Tan et al.
Background: The risk of congenital anomalies following first-trimester medication exposure is an important indicator of medication safety during pregnancy. Retrospective cohort studies using routinely collected data are c...
National Trends and Disparities in Herpes Zoster Vaccination Among US Older Adults With Diabetes, 2008-2023 [0.03%]
2008至2023年美国糖尿病老年群体带状疱疹疫苗接种的全国趋势及差异
Chun-Tse Hung,Li-Min Wang,Ding-Cheng Liu et al.
Chun-Tse Hung et al.
Purpose: To evaluate trends and disparities in herpes zoster vaccination among US older adults with diabetes. Methods: Data from the 20...
Performance of the Self-Controlled Case Series With Active Comparators for Drug Safety Signal Detection Using the Clinical Practice Research Datalink (CPRD) [0.03%]
利用临床实践研究数据链(CPRD)检测药物安全性信号的自我对照病例系列(SCR)分析效能研究：活性对照 vs 安慰剂对照
Astrid Coste,Angel Y S Wong,Francois Haguinet et al.
Astrid Coste et al.
Background: There is little evidence about signal detection using UK primary care electronic health records (EHRs). The self controlled case series (SCCS) is one of the most promising methods for drug safety signal detect...
Measuring Exposure to Opioids Using Self-Reported Medication Use Data Versus General Practitioner Prescription Records in the UK Biobank Study [0.03%]
英国生物银行研究中利用自我报告的用药数据和全科医生处方记录来测量阿片类药物接触度
Allison Domingues,Yue Zhai,Marie-Odile Parat et al.
Allison Domingues et al.
Purpose: The ongoing global increase in opioid use necessitates studies examining long-term health impacts. Prospective cohorts frequently rely on self-reported medication use data which may be subject to several types of...
Comparative Study
Pharmacoepidemiology and drug safety. 2025 Dec;34(12):e70280. DOI:10.1002/pds.70280 2025
Dipeptidyl Peptidase 4 Inhibitors: Novel Therapeutic Agents in the Management of Type II Diabetes Mellitus [0.03%]
二肽基肽酶4抑制剂——治疗2型糖尿病的新药
Chinyere Aloke,Oluwasola Abayomi Adelusi,Olalekan Olugbenga Onisuru et al.
Chinyere Aloke et al.
Background: Mounting evidence indicates that Type 2 diabetes mellitus (T2DM) is a public health challenge globally, and its occurrence is anticipated to surge in the forthcoming years. Dipeptidyl peptidase-4 (DPP-4) serve...
Risk of Major Congenital Malformations Associated With First-Trimester Exposure to Topical Antifungal Medications: A Large Claims Database Study [0.03%]
基于理赔数据库的孕早期局部抗真菌药物暴露与主要先天畸形关联性的研究
Tadaharu Kunitoki,Takamasa Sakai,Tomofumi Ishikawa et al.
Tadaharu Kunitoki et al.
Purpose: Vulvovaginal candidiasis is highly prevalent among pregnant women, and its treatment is crucial. However, there is a lack of evidence regarding the risks on fetal outcomes associated with the use of antifungal me...
Efficacy and Safety of All Monoclonal Antibodies in Moderate-to-Severe Atopic Dermatitis: A Systematic Review and Network Meta-Analysis [0.03%]
中重度特应性皮炎单克隆抗体疗法的有效性和安全性：系统评价和网络 meta 分析
Wenting Cai,Linlin Fu,Yan Wu et al.
Wenting Cai et al.
Objective: The aim of this study was to compare the efficacy and safety of monoclonal antibodies (mAb) for moderate-to-severe atopic dermatitis (AD). Meth...
High-Throughput Screening Using the Self-Controlled Tree-Based Scan Statistic to Identify Medications Associated With Hospitalization for Severe Acute Liver Injury [0.03%]
利用自我控制树型扫描统计量进行高通量筛查以识别与重度急性肝损伤住院相关药物
Vincent Lo Re rd,Craig W Newcomb,Dean M Carbonari et al.
Vincent Lo Re rd et al.
Background: Medications associated with acute liver injury (ALI) are primarily identified by case reports. High-throughput screening of real-world data could be leveraged to detect hepatotoxicity signals. ...
Concurrent Alcohol Use and the Relative Risk of Community-Acquired Pneumonia Associated With Anticholinergic and Non-Anticholinergic Neurocognitively Active Medication Receipt: A National Nested Case-Control Study Among US Veterans [0.03%]
同时饮酒与抗胆碱能和非抗胆碱能神经认知药物使用相关的社区获得性肺炎的相对风险：美国退伍军人中的一项全国嵌套病例对照研究
William H Wang,Kristina Crothers,Kathleen M Akgün et al.
William H Wang et al.
Purpose: Anticholinergic medications and alcohol each independently increase the risk of community-acquired pneumonia (CAP). Whether non-anticholinergic neurocognitively active medications also increase risk, and if alcoh...
Cardiovascular Effectiveness of Semaglutide Versus Dulaglutide in Type 2 Diabetes [0.03%]
在2型糖尿病患者中，索马鲁肽与杜拉鲁肽心血管结局的比较研究
Kasper Bonnesen,Uffe Heide-Jørgensen,Diana H Christensen et al.
Kasper Bonnesen et al.
Objective: Randomized clinical trials show that subcutaneous semaglutide is modestly superior to dulaglutide in reducing HbA1c and body weight, but no trial has compared their effectiveness on hard cardiovascular outcomes...
Comparative Study
Pharmacoepidemiology and drug safety. 2025 Dec;34(12):e70276. DOI:10.1002/pds.70276 2025