Uptake and Use of Biologic Therapies in Paediatric Immune-Mediated Inflammatory Diseases: An Australian Population-Based Study [0.03%]
澳大利亚生物制剂治疗儿科免疫介导性炎症性疾病的应用和使用：基于人口的全国研究
Jun Ni Ho,Jodie Hillen,Natasha Nassar et al.
Jun Ni Ho et al.
Purpose: To quantify the real-world use and describe characteristics of paediatric patients initiating biologic medicines for immune-mediated inflammatory diseases (IMIDs). ...
Comparative Effectiveness of Oral Fluoropyrimidines Versus FOLFOX as Adjuvant Therapy for Stage III Colon Cancer: A Retrospective Cohort Study Using Overlap-Weighted Restricted Mean Survival Time Analysis [0.03%]
氟尿嘧啶类口服药物与FOLFOX化疗作为III期结肠癌术后治疗的比较有效性：重叠加权限制平均生存时间分析的回顾性队列研究
Shih-Feng Huang,Chao-Wen Hsu,Chih-Chien Wu et al.
Shih-Feng Huang et al.
Purpose: Oxaliplatin-based chemotherapy is the standard adjuvant treatment for stage III colon cancer, but oral fluoropyrimidines remain widely used for patients unsuitable for combination therapy. Real-world data compari...
Comparative Study
Pharmacoepidemiology and drug safety. 2026 Jul;35(7):e70427. DOI:10.1002/pds.70427 2026
Association Between EGFR-TKI-Associated Skin Rash and Recorded Mortality in Non-Small Cell Lung Cancer: A Real-World Analysis Accounting for Immortal Time Bias [0.03%]
EGFR-TKI相关皮疹与非小细胞肺癌记录死亡率之间的关联：一项纠正不朽时间偏倚的真实世界分析
Yasutaka Ihara,Yukihiro Nakamura,Shoichiro Yamamoto
Yasutaka Ihara
Purpose: Skin rash during epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy has been associated with better outcomes in non-small cell lung cancer (NSCLC), but previous studies may have overest...
Nationwide Trends in Opioid Consumption in Costa Rica, 2017-2024: Implications for Regulatory Policy and Public Health [0.03%]
2017-2024年哥斯达黎加阿片类药物消耗的全国趋势及其对监管政策和公共卫生的影响
Esteban Zavaleta-Monestel,Sebastián Arguedas-Chacón,Jeaustin Mora-Jiménez et al.
Esteban Zavaleta-Monestel et al.
Introduction: The global opioid crisis has highlighted substantial differences in prescribing, monitoring, and regulatory practices across health systems. In Costa Rica, comprehensive national data on opioid use have been...
Mortality in Castration Resistant Prostate Cancer Patients With and Without Pre-Existing Cardiovascular Disease Receiving Oral Androgen Receptor Pathway Inhibitors [0.03%]
口服雄激素受体通路抑制剂治疗合并或不合并心血管疾病前列癌患者的死亡率
Ibrahim M Asiri,Ronald C Chen,Viraj Master et al.
Ibrahim M Asiri et al.
Background: Men with castration-resistant prostate cancer (CRPC) who have a pre-existing history of cardiovascular disease (CVD) or other comorbidities are often excluded from clinical trials involving oral androgen recep...
Comparative Study
Pharmacoepidemiology and drug safety. 2026 Jul;35(7):e70405. DOI:10.1002/pds.70405 2026
Trajectories Associated With the Use and Deprescription of Benzodiazepines and Z-Drugs in a Network of Geriatric Outpatient Clinics [0.03%]
老年人门诊患者使用苯二氮卓类和Z药物的历程轨迹分析
Nelson Machado do Carmo Júnior,Mariana Martins Gonzaga do Nascimento,Antônio Ignácio de Loyola Filho et al.
Nelson Machado do Carmo Júnior et al.
Purpose: To determine the trajectories of benzodiazepine (BZD) and Z-drug use among older adults (n = 3590) followed in a network of geriatric outpatient clinics in Brazil. ...
Provider Perspectives to Inform a Patient-Facing Decision Aid on Oral Corticosteroid Use During Pregnancy and Evaluation of the Aid [0.03%]
从供应商角度出发制定的孕期口服皮质类固醇用药患者决策辅助工具及其评估
Kristin Palmsten,Elisabeth A Seburg,Jeanette Y Ziegenfuss et al.
Kristin Palmsten et al.
Purpose: We previously identified patient need for a decision aid on oral corticosteroid (OCS) use during pregnancy that could be used to support discussions between providers and patients. In the current study, we aimed ...
Clinical Pharmacist Intervention Improves Adherence to Venous Thromboembolism Protocols [0.03%]
临床药师干预可改善静脉血栓栓塞症治疗的依从性
Anne Karollyne Soares Silva Leite,Leiliane Rodrigues Marcatto,Pedro Eduardo Nascimento Silva Vasconcelos et al.
Anne Karollyne Soares Silva Leite et al.
Purpose: Venous thromboembolism (VTE) is a preventable condition associated with an increased risk of morbidity and mortality in hospitalized patients. Pharmacological and/or mechanical prophylaxis can prevent thromboembo...
Observational Study
Pharmacoepidemiology and drug safety. 2026 Jul;35(7):e70418. DOI:10.1002/pds.70418 2026
Age, Age-Related Comorbidities and Survival in Palbociclib, Ribociclib and Abemaciclib Users With Advanced Breast Cancer: A Nation-Wide Retrospective Cohort Study [0.03%]
帕博西尼、瑞伯西利和阿贝西普利使用者晚期乳腺癌患者的年龄、与年龄相关的合并症及生存率：一项全国性的回顾性队列研究
Blair Rajamaki,Olli Tenhunen,Liisa Pylkkänen et al.
Blair Rajamaki et al.
Purpose: Prevalence of breast cancer (BC) increases with age, but the external validity of data obtained from pivotal trials of medicinal products remains a concern due to the underrepresentation of frail and older adults...
Using Natural Language Processing of Clinical Notes to Supplement Structured Electronic Health Record Data for Phenotyping Smoking and Obesity in a Healthcare System [0.03%]
利用自然语言处理临床记录补充结构化电子健康档案数据以表征医疗系统中的吸烟和肥胖现象
Jie Yang,Bowen Gu,Haritha Pillai et al.
Jie Yang et al.
Purpose: Studies based on electronic health records (EHR) often rely on structured data, which may incompletely capture important clinical phenotypes in EHR notes. The purpose of this study was to assess two natural langu...