DrugUtilisation: An R Package to Support Drug Utilisation Research Using the OMOP Common Data Model [0.03%]
药物利用分析：一个用于支持基于OMOP通用数据模型的药物利用研究的R语言包
Yuchen Guo,Edward Burn,Annika M Jödicke et al.
Yuchen Guo et al.
Purpose: To develop and describe DrugUtilisation, an open-source R package that facilitates drug utilisation studies using data mapped to the OMOP Common Data Model (CDM). ...
Hospitalization for Malignant Arrhythmias Following Initiation of Donepezil: A Retrospective Cohort Study [0.03%]
多奈哌齐使用后恶性心律失常住院的回顾性队列研究
Yichang Huang,John-Michael Gamble,David N Juurlink et al.
Yichang Huang et al.
Purpose: Limited evidence suggests donepezil might pose an increased risk of malignant arrhythmias. We examined whether donepezil initiation was associated with a higher risk of hospitalization for malignant arrhythmia co...
Novel Recruitment, Data Collection, and Safety Reporting Methods in the Era of COVID-19: Design of a Post-Emergency Use Authorization COVID-19 Vaccination Safety-Surveillance Study [0.03%]
新冠肺炎时代新的招募、数据收集和安全报告方法：一种关于新冠疫苗紧急使用授权后安全性监测研究的设计
Cherise Wong,Katherine Kendrick,Laura Webb et al.
Cherise Wong et al.
Purpose: Within one week of the Food and Drug Administration granting the COVID-19 vaccine Emergency Use Authorization, the HERO-Together study launched. We describe how the study utilized novel methods for streamlined en...
Observational Study
Pharmacoepidemiology and drug safety. 2026 Jul;35(7):e70431. DOI:10.1002/pds.70431 2026
Core Concepts in Pharmacoepidemiology-Round 3: Call for Writing Groups [0.03%]
药物流行病学核心概念第三轮征稿：写作小组报名通知
Kristian B Filion,Jennifer L Lund
Kristian B Filion
How Negative Controls Are Used in Pharmacoepidemiology: A Methodological Scoping Review of Real-World Observational Studies of Glucagon-Like Peptide-1 Receptor Agonists [0.03%]
药物流行病学中阴性对照的使用方法：胰高血糖素样肽-1受体激动剂真实世界观察性研究的系统评价
Zhengxuan Li,Yinan Huang,Hua Chen et al.
Zhengxuan Li et al.
Negative controls (NCs) are increasingly used in real-world observational studies to detect residual confounding and systematic bias, but their implementation and reporting remain heterogeneous in applied pharmacoepidemiology. We conducted ...
A Drug-Environment Interaction Between PM2 .5 Concentration and Corticosteroid Use on Cardiovascular and Thromboembolic Events in Older Adults [0.03%]
老年人中空气动力学直径小于等于2.5微米的颗粒物与皮质类固醇使用对心血管和血栓事件相互作用的影响研究
Shu-Ping Huang,Chien-Chou Su,Rachel Nethery et al.
Shu-Ping Huang et al.
Background: Few studies have investigated the interaction between drug-environment despite the plausibility and concern. We sought to explore the synergistic effects of corticosteroids and PM2.5 on cardiovascular and thro...
Association Between Socioeconomic Conditions and Biologic Prescriptions for Inflammatory Bowel Diseases in the Brazilian Public Healthcare System: An Ecological Study [0.03%]
巴西公共医疗系统中社会经济状况与炎症性肠病生物制剂处方的生态学研究关联性分析
Caroline Tianeze de Castro,Luciane Cristina Feltrin de Oliveira,Carlos Antonio de Souza Teles Santos et al.
Caroline Tianeze de Castro et al.
Purpose: Inflammatory bowel diseases (IBD) are chronic conditions affecting millions of people globally. Brazil's public healthcare system provides free access to IBD medications. However, socioeconomic conditions may aff...
Effectiveness of Metformin in Preventing Colorectal Cancer Among Japanese Patients With Type 2 Diabetes: A Target Trial Emulation [0.03%]
二甲双胍在日本2型糖尿病患者中预防结直肠癌的有效性：靶标试验模拟研究
Shunsuke Hiroki,Toshiki Fukasawa,Munenori Honda et al.
Shunsuke Hiroki et al.
Purpose: Observational studies have repeatedly reported lower cancer incidence among metformin users than nonusers, but findings are inconsistent and often affected by issues such as immortal time, unclear comparators, an...
Trends in Pharmacist-Prescribed Dispensing Records of HIV Pre-Exposure (2020-2025) and Post-Exposure Prophylaxis (2020-2024) in Brazil: A Time Series Analysis [0.03%]
巴西2020-2025年抗逆转录病毒药物暴露前预防和2020-2024年暴露后预防的药剂师处方趋势：时间序列分析
Gustavo Magno Baldin Tiguman,Dyego Carlos Souza Anacleto de Araújo,Patricia Melo Aguiar
Gustavo Magno Baldin Tiguman
Purpose: Pharmacist prescribing of HIV pre-exposure (PrEP) and post-exposure prophylaxis (PEP) is an emerging strategy to expand access to HIV prevention, but real-world evidence on its implementation remains limited. We ...
French Consumption of Methylphenidate in Primary Care From 2016 to 2023, Impact of Prescribing Policy Changes-A Time-Series Analysis [0.03%]
法国2016年至2023年基层医疗中哌甲酯的消费情况：处方政策变化的影响-时间序列分析
Claire Saudreau,Vincent Tarazona,David De Bandt
Claire Saudreau
Purpose: In France, methylphenidate, mainly used in the treatment of ADHD, has been subject to prescription restrictions that were relaxed at the end of 2021. This study analyses trends in methylphenidate consumption in F...