Discontinuation of Renin-Angiotensin System Inhibitors and Risk of End-Stage Renal Disease and Cardiovascular Outcomes Among Patients With Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Taiwanese Cohort Study [0.03%]
糖尿病肾病患者停用肾素血管紧张素系统阻断剂与终末期肾病及心血管结局的关联：一项台湾全国性队列研究
Yaa-Hui Dong,Chia-Hsuin Chang,Li-Chiu Wu et al.
Yaa-Hui Dong et al.
Purpose: This nationwide cohort study examined the effects of discontinuation versus continuation of renin-angiotensin system inhibitors (RASis) on major renal and cardiovascular outcomes after the estimated glomerular fi...
Filling the Gaps in Health Data: Using a Machine Learning Approach to Augment Partially Observed Variables Such as Smoking in Claims Data [0.03%]
利用机器学习方法完善健康档案数据中的吸烟等观测不完整的变量
Stefan Franzen,Evangelos Chandakas,Sam Hillman et al.
Stefan Franzen et al.
Purpose: Missing information is common in real-world claims data, particularly on behavioral confounders, for example, smoking. Often one category of the variable, "yes" is partially observed while the other "no" remains ...
Observational Study
Pharmacoepidemiology and drug safety. 2026 Feb;35(2):e70322. DOI:10.1002/pds.70322 2026
Psychotropic Use Among Classroom Teachers in Espírito Santo: A Cross-Sectional Study [0.03%]
埃斯皮里图圣蒂地区教室教师的使用精神活性物质的行为：一项横断面研究
Yohan Cancilheri Mazzini,Paulo Vitor Ramos Vitori,Kimberly Domingos Schneider et al.
Yohan Cancilheri Mazzini et al.
Purpose: To assess the prevalence of psychotropic use among classroom teachers and to identify associated factors. Methods: A cross-sec...
Comparing Different As-Treated Approaches: A Methodological Study Using Real-World Data on Psoriasis Treatments [0.03%]
不同强效疗法的比较：使用真实世界数据进行的银屑病治疗方法论研究
Sejun Kim,Andreas Jensen,Alexander Egeberg et al.
Sejun Kim et al.
Background: Accurate pharmaco-epidemiological assessment of the safety of biological treatments is essential but methodologically challenging. Aims: ...
Comparative Study
Pharmacoepidemiology and drug safety. 2026 Feb;35(2):e70337. DOI:10.1002/pds.70337 2026
Impact of COVID-19 Restrictions on Nationwide Antipsychotic Use: Results From the Trends in Drug Utilization During COVID-19 Pandemic in Turkey (PANDUTI-TR) Study [0.03%]
土耳其新冠疫情下的全国抗精神病药物使用情况：来自“新冠疫情期间的土耳其药物利用趋势研究（PANDUTI-TR）”的结果
Caner Vizdiklar,Volkan Aydin,Hakan Yilmaz et al.
Caner Vizdiklar et al.
Introduction: The extraordinary circumstances due to the COVID-19 pandemic and related restrictions altered the management of mental health disorders, including the use of antipsychotics. We aimed to examine the changes i...
High-Dimensional Propensity Scores for Mitigating Confounding: Implementation Using Primary and Secondary Care Data in Hong Kong [0.03%]
基于主客观数据的高维倾向值评分在香港的应用研究
Edmund C L Cheung,Min Fan,Celine S L Chui et al.
Edmund C L Cheung et al.
Purpose: Confounding is a key concern in observational studies using healthcare databases. The high-dimensional propensity score (HDPS) algorithm is an approach for generating and prioritising proxy variables, leveraging ...
Development and Validation of an Endometrial Cancer Algorithm in US Claims Data [0.03%]
基于美国医疗费用数据的子宫内膜癌算法的开发与验证
Kimberly Daniels,Cachet Wenziger,Sampada Gandhi et al.
Kimberly Daniels et al.
Purpose: This study developed and validated algorithms to identify the incidence of endometrial cancer using ICD-9-CM and ICD-10-CM coding systems as part of a post-authorization safety study (EU PAS: EUPAS45602) of vagin...
Antihypertensive Past Adherence Trajectories and Risk of Cardiotoxicity Among Adults Initiating Anthracycline Treatment [0.03%]
既往降压药依从性轨迹与开始使用蒽环类药物治疗的成人发生心脏毒性的风险关系研究
Udim Damachi,Eberechukwu Onukwugha,Manu Murali Mysore et al.
Udim Damachi et al.
Background: Poor blood pressure control and low adherence to antihypertensives increase the risk for anthracycline-induced cardiotoxicity (AIC) in hypertensive cancer patients. Little is known about whether past adherence...
Comparative Effectiveness of Levonorgestrel Implant and Depot Medroxyprogesterone Acetate Injectable for Women Living With HIV on Dolutegravir-Based Antiretroviral Therapy [0.03%]
杜鲁特格拉韦抗逆转录病毒治疗的HIV感染女性使用左炔诺孕酮植入剂和醋酸地屈孕酮注射剂的效果比较研究
Katie R Mollan,Brian W Pence,Daniel Westreich et al.
Katie R Mollan et al.
Background: Dolutegravir (DTG)-based antiretroviral treatment (ART) is broadly prescribed to treat HIV. Effective family planning methods are important for the health of women with HIV (WWH) and their families. For WWH on...
Comparative Study
Pharmacoepidemiology and drug safety. 2026 Feb;35(2):e70297. DOI:10.1002/pds.70297 2026