Gastrointestinal bleeding risk with rivaroxaban vs aspirin in atrial fibrillation: A multinational study [0.03%]
利伐沙班与阿司匹林在房颤中引起胃肠道出血风险的多国研究
Laura Fanning,Ian C K Wong,Xue Li et al.
Laura Fanning et al.
Purpose: Comparative gastrointestinal bleeding (GIB) risk between rivaroxaban and low-dose aspirin is unknown in patients with atrial fibrillation (AF). This study investigated GIB risk with rivaroxaban vs aspirin among t...
Medications used disproportionately during pregnancy: Priorities for research on the risks and benefits of medications when used during pregnancy [0.03%]
妊娠期间使用过度的药物：确定妊娠期间用药的风险和益处的研究重点
Alys Havard,Sebastiano Barbieri,Mark Hanly et al.
Alys Havard et al.
Purpose: To identify medications used disproportionately more or less among pregnant women relative to women of childbearing age. Methods: ...
Validity of diagnosis and procedure codes for identifying neural tube defects in infants [0.03%]
诊断和程序编码在识别婴儿神经管缺陷的有效性研究
T Craig Cheetham,Sascha Dublin,Gaia Pocobelli et al.
T Craig Cheetham et al.
Purpose: The use of validated criteria to identify birth defects in electronic healthcare databases can avoid the cost and time-intensive efforts required to conduct chart reviews to confirm outcomes. This study evaluated...
Assessing the impact of unmeasured confounders for credible and reliable real-world evidence [0.03%]
评估未测量混杂因素对可信和可靠的真实世界证据的影响
Xiang Zhang,James D Stamey,Maya B Mathur
Xiang Zhang
Purpose: We review statistical methods for assessing the possible impact of bias due to unmeasured confounding in real world data analysis and provide detailed recommendations for choosing among the methods. ...
Drug utilization study on immediate release Fentanyl in Spain. Prevalence, incidence, and indication [0.03%]
芬太尼在西班牙的使用研究。流行病学、发病率和适应症
Diana González-Bermejo,Pilar Rayón-Iglesias,Alfonso Rodríguez-Pascual et al.
Diana González-Bermejo et al.
Purpose: We aimed to characterize the trends of immediate release fentanyl (IRF) use in Spain between 2012 and 2017 and indication for its use. IRF drugs are rapid-acting opioids approved to treat breakthrough cancer pain...
Implementing high-dimensional propensity score principles to improve confounder adjustment in UK electronic health records [0.03%]
在英国电子健康记录中实施高维倾向得分原则以改善混杂因素的调整
John Tazare,Liam Smeeth,Stephen J W Evans et al.
John Tazare et al.
Purpose: Recent evidence from US claims data suggests use of high-dimensional propensity score (hd-PS) methods improve adjustment for confounding in non-randomised studies of interventions. However, it is unclear how best...
Improving transparency to build trust in real-world secondary data studies for hypothesis testing-Why, what, and how: recommendations and a road map from the real-world evidence transparency initiative [0.03%]
为了建立对现实世界二级数据研究的信任需提高透明度 - 为什么，什么，怎么做：来自真实世界证据透明度计划的建议和路线图
Lucinda S Orsini,Brigitta Monz,C Daniel Mullins et al.
Lucinda S Orsini et al.
Real-world data (RWD) and the derivations of these data into real-world evidence (RWE) are rapidly expanding from informing healthcare decisions at the patient and health system level to influencing major health policy decisions, including ...
Assessment of colistimethate sodium (COLOBREATHE) risk minimization measures implemented in the European Union: A cross-sectional study [0.03%]
硫酸_colistimethate(百泌达)在欧盟实施的风险最小化措施评估：一项横断面研究
Sigal Kaplan,Oliver Patino,Carolyn Rainville et al.
Sigal Kaplan et al.
Purpose: To assess the effectiveness of additional risk minimization measures (aRMMs) implemented in Europe for colistimethate sodium (CMS) among healthcare professionals (HCPs) and patients/caregivers following safety co...
Validation of algorithms to estimate gestational age at birth in the Medicaid Analytic eXtract-Quantifying the misclassification of maternal drug exposure during pregnancy [0.03%]
验证算法以估计出生时的妊娠年龄-量化怀孕期间母体药物暴露的误分类问题
Yanmin Zhu,Christian Hampp,Xi Wang et al.
Yanmin Zhu et al.
Purpose: Accurate ascertainment of gestational age (GA) has been a challenge in perinatal epidemiologic research. To date, no study has validated GA algorithms in Medicaid Analytic eXtract (MAX). ...
Proton pump inhibitors and chronic kidney disease: Reevaluating the evidence from a randomized controlled trial [0.03%]
质子泵抑制剂与慢性肾脏病：来自随机对照试验的证据重新评估
B Burt Gerstman
B Burt Gerstman