One-Day Brentuximab-Bendamustine (120 mg/m2) Every 21 Days is a Feasible, Safe and Effective Treatment for Relapsed/Refractory Hodgkin Lymphoma [0.03%]
一天一次本妥西单抗-苯达莫司汀（120毫克/平方米）每21天为复发/难治性霍奇金淋巴瘤的可行、安全和有效治疗方案
H Moatti,P Brice,M-C Laroque et al.
H Moatti et al.
Brentuximab vedotin (BV)-bendamustine (90 or 120 mg/m2 day 1 and 2) every 28 days is an effective treatment for relapsed/refractory Hodgkin lymphoma (R/R HL) but associated to high toxicity especially for elderly patients. We conducted in S...
Implications of Genetic, Biological and Clinical Parameters in Patients With Richter Syndrome: A Monocentric Experience [0.03%]
遗传学、生物学和临床参数在里特尔氏综合征患者中的影响：单中心经验报告
Idanna Innocenti,Tommaso Quaranta,Annamaria Tomasso et al.
Idanna Innocenti et al.
Impact of C-MYC/BCL2 Double Expression on Survival Outcomes After Autologous Transplantation in Relapsed/Refractory Diffuse Large B Cell Lymphoma-A Nationwide Retrospective Analysis in Singapore [0.03%]
C-MYC/BCL2双蛋白表达对新加坡复发/难治弥漫性大B细胞淋巴瘤自体移植患者生存结局的影响——一项全国性的回顾性分析研究
Jing Yuan Tan,Victor Wei Teik Ling,Lawrence Cheng Kiat Ng et al.
Jing Yuan Tan et al.
Baseline Tumor Burden Assessed With AI-Guided PET/CT Total Metabolic Tumor Volume (TMTV) and LDH Levels Predict Efficacy of CAR-T in Aggressive B-Cell Lymphoma [0.03%]
基线肿瘤负荷采用人工智能引导的PET/CT总代谢肿瘤体积(TMTV)和LDH水平预测CAR-T治疗侵袭性B细胞淋巴瘤的效果
Eugenio Galli,Andrea Guarneri,Federica Sorà et al.
Eugenio Galli et al.
Disease burden is a critical determinant of outcomes in CAR-T therapy for B-cell lymphomas, and one of the most widely used techniques for its assessment is Total Metabolic Tumor Volume (TMTV) measured via [18F]FDG PET/CT. Biological parame...
Molecular Profiling Identifies CD49d and CD79b as Predictive Markers for Acquired Acalabrutinib Resistance in Patients With Chronic Lymphocytic Leukemia [0.03%]
分子分型鉴定出CD49d和CD79b是慢性淋巴细胞白血病患者获得性阿卡替尼耐药的预测标志物
Elena Bibikova,Sara Parsa,Muskan Floren et al.
Elena Bibikova et al.
Contemporary studies of Bruton tyrosine kinase inhibitor (BTKi) resistance focus on mutations in the B-cell receptor (BCR) pathway, but alternative mechanisms of resistance remain undefined. Here, we sought to identify novel predictive mark...
Clinical Trial
Hematological oncology. 2025 Jan;43(1):e70008. DOI:10.1002/hon.70008 2025
Different Role of PET-CT Evaluation in Newly Diagnosed Follicular Lymphoma Upon Rituximab-Based Chemotherapy and Chemo-Free Immunotherapy [0.03%]
利妥昔单抗为基础的化疗及无化疗免疫治疗初治滤泡性淋巴瘤患者PET-CT评估作用不同
Nan Wang,Xin-Yun Huang,Xu-Feng Jiang et al.
Nan Wang et al.
Newly diagnosed follicular lymphoma (FL) patients usually received first-line rituximab-based immunochemotherapy (R-chemo). Recently, rituximab plus lenalidomide (R2) emerged as an alternative chemo-free immunotherapy. We performed a compar...
Post-CAR T-Cell Therapy Failure Metabolic Parameters Predict Survival and Response in Large B-Cell Lymphoma [0.03%]
CAR-T细胞治疗后的大B细胞淋巴瘤患者的代谢特征与其生存和疗效相关性研究
Hazim S Ababneh,Matthew J Frigault,Andrea K Ng et al.
Hazim S Ababneh et al.
18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) parameters have shown a significant prognostic role in relapsed/refractory large B-cell lymphoma (LBCL) patients undergoing CD19-targeted chimeric anti...
Combining Total Metabolic Tumor Volume With Beta-2-Microglobulin Levels Predicts Outcomes in High-Burden Follicular Lymphoma Patients [0.03%]
总代谢肿瘤容积与β2微球蛋白水平联合预测高负荷型滤泡淋巴瘤患者的预后
A Zduniak,E Lévêque,S Draye-Carbonnier et al.
A Zduniak et al.
We aimed to explore the predictive value of total metabolic tumor volume (TMTV) and beta-2-microglobulin (B2M) levels in patients with follicular lymphoma (FL) with a high tumor burden receiving standard first-line immunochemotherapy. We an...
Long-Term Outcomes of Reduced-Toxicity Conditioning Using 8-Gray Total Body Irradiation, Fludarabine, and Cyclophosphamide in Children, Adolescents, and Young Adults With Hematological Malignancies [0.03%]
用于血液系统恶性肿瘤儿童、青少年和年轻成人的减毒预处理方案(8Gy全身照射氟达拉滨环磷酰胺)的长期结果
Hirokazu Morokawa,Koichi Hirabayashi,Yu Furui et al.
Hirokazu Morokawa et al.
Recent studies have indicated that total body irradiation (TBI)-based reduced-toxicity conditioning (RTC) may be a potential treatment modality, especially in adults with leukemia. However, its efficacy and safety in children with hematolog...
Ceiling Effect of International Myeloma Working Group Frailty Score in Real-World Population of Older Adults With Cancer [0.03%]
国际骨髓瘤工作组衰弱评分在老年实体肿瘤患者中存在天花板效应
Carla T Williams,Cenk Yildirim,Mayuri Dharne et al.
Carla T Williams et al.