Simultaneous Determination of Six Inorganic Anions in Animal Whole Blood Using Ion Chromatography With Suppressed Conductivity Detection [0.03%]
应用阴离子交换色谱-电导检测法同时测定动物全血中的六种无机阴离子
Babita Dhanik,Pallavi Khandelia,Aakanksha Paliwal et al.
Babita Dhanik et al.
A sensitive and robust ion chromatography method with suppressed conductivity detection (IC-CD) was developed and validated for the simultaneous quantification of six inorganic anions (fluoride, nitrite, bromide, nitrate, phosphate, and sul...
Pharmacokinetic, Bioavailability, and Excretion Study of Hypaphorine Following Intragastric and Intravenous Administration in Rats Using Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometry [0.03%]
超高效液相色谱-串联质谱法测定异帕弗林在大鼠口服和静脉给药后的药动学、生物利用度及排泄研究
YinDan Fu,Yu Shao,Yuli Shen
YinDan Fu
Hypaphorine is an indole alkaloid from Erythrina velutina, which exerts excellent anti-inflammatory and antioxidant properties. In this study, a simple liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed and valid...
Comprehensive Evaluation of Growth Period Variations in Bioactive Properties and Phytochemical Profiles of Aesculus chinensis Bge Seeds and Leaves [0.03%]
中国七叶树种子和叶片生长期内生物活性及植化指标的综合评价
Yu Liu,Dongju Ren,Yanchen Liu et al.
Yu Liu et al.
In China, Aesculus chinensis Bge (A.Bge) is known as a medicinal plant. A.Bge seeds have been traditionally used to relieve abdominal distention and stomach pain, whereas studies on A.Bge leaves remain limited. This study aimed to clarify t...
Sophora tonkinensis Alleviates Progression of Diethylnitrosamine-Induced Hepatocellular Carcinoma in Rats via Multitarget Regulation [0.03%]
Sophora tonkinensis通过多靶点调控抑制二乙基亚硝胺诱导的肝癌小鼠模型中肝细胞癌的发展
Zongliang Lu,Jincai Wen,Chengwei Li et al.
Zongliang Lu et al.
Sophora tonkinensis, a traditional Chinese medicine with heat-clearing, detoxifying, and throat-soothing properties, has shown potential in treating hepatitis, inhibiting tumors, and regulating immunity, but its active constituents and mech...
Effectiveness of Chromolaena odorata Extracts Against Cercariae From Schistosoma mansoni: Pharmacological Related Properties and Phytochemical Profile [0.03%]
毛瓣臭草提取物对曼氏血吸虫 cercariae 的作用及其药理学和植物化学性质研究
Dongmo Nguepi Mireille Sylviane,Itoe Ubre Sicca,Sofeu Feugaing David Denis et al.
Dongmo Nguepi Mireille Sylviane et al.
Schistosomiasis, a parasitic disease transmitted by freshwater snails, affects over 251.4 million people globally, with sub-Saharan Africa bearing 95% of the disease burden. This study evaluates the phytochemical composition, characterizes ...
Spectrum-Effect Relationship-Based Analysis of Pneumonia Mixture Used for Pneumonia Treatment [0.03%]
基于谱效应关系的肺炎合剂抗炎作用研究
Hai-Bo Zhang,Yue-Hong Gong,Rena Maimaiti et al.
Hai-Bo Zhang et al.
The pneumonia mixture has demonstrated significant therapeutic effects against pneumonia; however, its active compounds remain poorly understood. The spectrum-effect relationship is a method for studying correlations between chemical spectr...
Quality-by-Design-Driven Development and Validation of a Sensitive HPLC Method for Trace-Level Determination of Nitrosamine Impurity in a Muscle Relaxant Drug Formulation [0.03%]
基于质量设计的开发和验证用于肌肉松弛剂制剂中亚硝胺杂质痕量检测的HPLC方法
Vinod Kumar Manglige,Syam Sundhar Sai Kumar Boppana,Kiran Kumar Chagarlamudi et al.
Vinod Kumar Manglige et al.
N-Nitroso impurities are very hazardous genotoxic carcinogens that can occur as by-products or breakdown products in pharmaceutical compounds. In this study, a sensitive and quality-by-design-based high-performance liquid chromatography met...
A Rapid and Sensitive HPLC-MS/MS Method for Quantification of Propranolol in Rat Plasma and the Application to Pharmacokinetic Study [0.03%]
一种快速灵敏测定大鼠血浆普萘洛尔的HPLC-MS/MS方法及其药代动力学应用
Li Bei,Huang Haijin,Wan Lili et al.
Li Bei et al.
A novel HPLC-MS/MS method has been developed for the determination of propranolol in rat plasma in the present study. The analytes of interest were retained and separated on a C18 column, and a triple-quadrupole mass spectrometry equipped w...
UPLC-MS/MS-Based Cellular Pharmacokinetics of Four Active Components of Total Glucosides of Picrorhizae Rhizome and Target Validation for ACLY [0.03%]
基于UPLC-MS/MS的胡黄连根茎总 glucosides 四种活性成分细胞药动学研究及ACLY靶标确证
Yifang Zhang,Xiangyang Wang,Miao Qiao et al.
Yifang Zhang et al.
Total glucosides of picrorhizae rhizome (TGPR) are a promising candidate drug for treating non-alcoholic steatohepatitis (NASH). To clarify the material basis underlying its efficacy, it is crucial to characterize the cellular pharmacokinet...
Comparative Evaluation of Analytical Methods for the Determination of Insecticide Residues in Green Chilli (Capsicum annuum L.) Fruits [0.03%]
几种杀虫剂残留检测方法在绿辣椒(Capsicum annuum L.)中应用效果比较评价研究
Akshita Sharma,Sapna Katna,Tanuja Banshtu et al.
Akshita Sharma et al.
This study compares four different analytical methods for residue extraction to establish an efficient and cost-effective sample analysis method for green chilli matrix after spiking. Modified Dutch mini-Luke method, ethyl acetate extractio...
Comparative Study
Biomedical chromatography : BMC. 2026 Jun;40(6):e70471. DOI:10.1002/bmc.70471 2026