Sex-Related Differences and Predictors of Mortality in Patients Undergoing Major Orthopaedic Surgery: Insights from the ORTHO-START Registry [0.03%]
性别相关差异和接受重大骨科手术患者的死亡率预测因素：来自ORTHO-START注册中心的见解
Elvira Grandone,Emilia Antonucci,Gregory Piazza et al.
Elvira Grandone et al.
Sex-related differences in outcomes after major orthopaedic surgery remain under-investigated, and the prognostic relevance of a history of venous thromboembolism (VTE) is unclear. The ORTHO-START registry is a prospective, multicenter stud...
Clinical Trial
Seminars in thrombosis and hemostasis. 2026 Jul 31. DOI:10.1055/a-2918-4154 2026
Integrated Model Linking Hemolysis, NETosis, Ferroptosis, Lysosomal Dysfunction, and DIC in Sepsis [0.03%]
脓毒症中溶血、NET形成、铁死亡、溶酶体功能障碍和DIC的综合模型链接研究
Toshiaki Iba,Cheryl L Maier,Ricard Ferrer et al.
Toshiaki Iba et al.
Sepsis-associated coagulopathy (SIC) and disseminated intravascular coagulation (DIC) are major determinants of organ failure and mortality in sepsis. While traditionally viewed as disorders of coagulation and fibrinolysis, emerging evidenc...
Large Language Models for Viscoelastic Tests: A Head-to-Head Evaluation of ChatGPT, Gemini, and DeepSeek for Thromboelastography and ROTEM Interpretation [0.03%]
用于粘弹性测试的大语言模型：ChatGPT、Gemini和DeepSeek在血栓弹力图（TEG）和旋转血栓弹力计（ROTEM）解读中的头对头评估
Jun Kai Yeong,Mauro Panigada,Mohammad Ahmad Altememi et al.
Jun Kai Yeong et al.
Reply to the Correspondence: "Heterogeneity Among Plasma-Derived von Willebrand Factor Concentrates: Implications for Comparative Effectiveness Analyses" [0.03%]
关于来信的回复：“血浆衍生的血管性假血友病因子浓缩物的异质性：对比较有效性分析的影响”
Valérie Horvais,Catherine Ternisien,Julien Denis Le Sève et al.
Valérie Horvais et al.
Platelet-Count-Guided Low Molecular Weight Heparin Management of Catheter-Related Thrombosis in a Large Cohort of Patients with Newly Diagnosed Acute Leukemia [0.03%]
基于血小板计数指导的大分子量肝素管理新的急性白血病患者的导管相关血栓形成的一项大型队列研究
Shay Perek,Niv Izhaki,Ron Hoffman et al.
Shay Perek et al.
Treatment of catheter-related thrombosis (CRT) in acute leukemia patients is challenging due to concomitant thrombocytopenia. Although modified-dose anticoagulation is frequently used in this setting, several vital outcomes remain unclear. ...
Platelets in Children: Physiological Function, Developmental Regulation, and Clinical Significance in Disease States [0.03%]
儿童血小板的生理功能、发育调控及疾病状态下的临床意义
Natasha Letunica,Paul Monagle,Chantal Attard
Natasha Letunica
Platelets play a fundamental role in hemostasis; however, their phenotype, reactivity, and function vary across the pediatric age spectrum. While developmental differences in plasma coagulation proteins have been well-characterized in child...
Emmanuel J Favaloro,Benjamin Reardon,Leonardo Pasalic
Emmanuel J Favaloro
Haemostasis reflects a balance between procoagulant and anticoagulant forces. A relative excess of procoagulant forces and/or a relative lack of anticoagulant forces can predispose individuals to an increased risk of thrombosis. Conversely,...
Konstantina Tsante,Eleni Petrou,Stavros Tsalas et al.
Konstantina Tsante et al.
Gut microbiome has emerged as an important modulator of thrombotic disease through complex immunometabolic and interorgan pathways. Microbiome-derived metabolites have been associated with platelet activation, endothelial injury, and advers...
Bridging the Gap in Laboratory Monitoring of Extended Half-Life Factor VIII and IX: Can Thrombin Generation Assays Overcome Assay Discrepancies? [0.03%]
长效FVIII和FIX实验室监测的差距：凝血酶生成检测能否克服检验差异？
Monica Sacco,Raimondo De Cristofaro,Stefano Lancellotti
Monica Sacco
The management of hemophilia A has been transformed by the introduction of extended half-life factor VIII (EHL-FVIII) products. Similarly, the development of extended half-life factor IX (EHL-FIX) products has also impacted the treatment of...
External Quality Assessment for Low Molecular Weight Heparin Monitoring in the Australasia/Asia-Pacific Region [0.03%]
亚太地区的低分子肝素外部质量评估
Emmanuel J Favaloro,Sandya Arunachalam,Leonardo Pasalic
Emmanuel J Favaloro
Low molecular weight heparin (LMWH) remains a widely utilized parenteral anticoagulant in hospital and outpatient settings for thromboprophylaxis and treatment of venous thromboembolism. While LMWH typically does not require routine monitor...