Lynn Y-W Shong,David C-L Lam
Lynn Y-W Shong
Lung cancer remains the leading cause of cancer-related deaths worldwide, with its burden shaped by evolving risk factors, demographic changes, and healthcare disparities. Over the past decades, while age-standardized incidence and mortalit...
Daniel Scullin,Joseph Barney
Daniel Scullin
Neuromuscular diseases encompass a wide array of clinical manifestations, age at presentation, and severity of morbidity and mortality. Central to most patients with these disorders are symptoms of dyspnea and increased work of breathing re...
Peeling Back the Layers of the Bleomycin Model of Lung Fibrosis: Lessons Learned, Factors to Consider, and Future Directions [0.03%]
剥开肺纤维化博来霉素模型的层面：吸取教训、考虑因素和未来方向
Patricia Brazee,Nancy Allen,Rachel Knipe et al.
Patricia Brazee et al.
Bleomycin-induced lung injury remains the most widely used and well-characterized experimental model for studying pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF). This review provides a comprehensive analysis of the ble...
Matthew Triplette,Melinda C Aldrich
Matthew Triplette
Lung cancer is the leading cause of cancer deaths worldwide, claiming more lives than other age-related and screen-detectable cancers. Cigarette smoking remains the most important risk factor. However, despite common perceptions, risk is no...
Yunan Nie,Anne C Chiang
Yunan Nie
Small-cell lung cancer (SCLC) is a high-grade, aggressive neuroendocrine tumor with a particularly poor prognosis, characterized by early metastases and rapid development of therapy resistance. There have historically been few treatment opt...
Ferran Barbé,Adriano D S Targa,David Gozal
Ferran Barbé
Kathleen McAvoy,Jennifer Possick
Kathleen McAvoy
Drug-induced pneumonitis is a significant and potentially life-threatening complication associated with multiple lung cancer therapies. As novel therapies are introduced and incorporated into updated treatment algorithms, it is crucial to a...
Priyanka Singh,Shanda Edjah,Wei Shi et al.
Priyanka Singh et al.
Pulmonary fibrosis is characterized by scarring and thickening of the lung parenchyma due to excessive deposition of collagen and other extracellular matrix (ECM) proteins. This leads to disruption of gas exchange areas and ultimately respi...
Emerging Concepts in Therapeutic Interventions for Idiopathic Pulmonary Fibrosis [0.03%]
特发性肺纤维化治疗新概念
Cody A Schott,Michael P Mohning,Joseph Cooley
Cody A Schott
Idiopathic pulmonary fibrosis (IPF) is a rare but devastating diagnosis for patients with only two approved drug therapies. Extensive preclinical studies have identified and characterized novel pathways driving IPF pathogenesis, and researc...
Frank Detterbeck,Sora Ely,Edith M Marom et al.
Frank Detterbeck et al.
There is increased recognition that some lung cancers arise from or are associated with air-filled cystic spaces. Recognition of precursors is important because these are often overlooked and because some of these cancers progress rapidly o...