Matthew Triplette,Melinda C Aldrich
Matthew Triplette
Lung cancer is the leading cause of cancer deaths worldwide, claiming more lives than other age-related and screen-detectable cancers. Cigarette smoking remains the most important risk factor. However, despite common perceptions, risk is no...
Yunan Nie,Anne C Chiang
Yunan Nie
Small-cell lung cancer (SCLC) is a high-grade, aggressive neuroendocrine tumor with a particularly poor prognosis, characterized by early metastases and rapid development of therapy resistance. There have historically been few treatment opt...
Ferran Barbé,Adriano D S Targa,David Gozal
Ferran Barbé
Kathleen McAvoy,Jennifer Possick
Kathleen McAvoy
Drug-induced pneumonitis is a significant and potentially life-threatening complication associated with multiple lung cancer therapies. As novel therapies are introduced and incorporated into updated treatment algorithms, it is crucial to a...
Priyanka Singh,Shanda Edjah,Wei Shi et al.
Priyanka Singh et al.
Pulmonary fibrosis is characterized by scarring and thickening of the lung parenchyma due to excessive deposition of collagen and other extracellular matrix (ECM) proteins. This leads to disruption of gas exchange areas and ultimately respi...
Emerging Concepts in Therapeutic Interventions for Idiopathic Pulmonary Fibrosis [0.03%]
特发性肺纤维化治疗新概念
Cody A Schott,Michael P Mohning,Joseph Cooley
Cody A Schott
Idiopathic pulmonary fibrosis (IPF) is a rare but devastating diagnosis for patients with only two approved drug therapies. Extensive preclinical studies have identified and characterized novel pathways driving IPF pathogenesis, and researc...
Frank Detterbeck,Sora Ely,Edith M Marom et al.
Frank Detterbeck et al.
There is increased recognition that some lung cancers arise from or are associated with air-filled cystic spaces. Recognition of precursors is important because these are often overlooked and because some of these cancers progress rapidly o...
Surgical therapy for stage I lung cancer - lobar versus sublobar resection [0.03%]
一期肺癌的外科治疗：肺叶切除术与亚肺叶切除术
Sarah Rudasill,Farhood Farjah
Sarah Rudasill
Lung cancer is a leading cause of cancer-related mortality, but advances in screening and early detection have improved opportunities for curative treatment. Therapeutic intent surgical resection remains a cornerstone for managing clinical ...
Ishan Paranjpe,Alexander Salter,Kenneth Chen et al.
Ishan Paranjpe et al.
Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide. The past two decades have brought advances in molecular profiling and the advent of therapies that specifically target genetic and/or molecular altera...
Duc M Ha,Regina A Jacob,Brett Bade
Duc M Ha
The number of lung cancer survivors - anyone living with and beyond a lung cancer diagnosis - is increasing along with advances in screening, early detection, and treatment. Following diagnosis and treatment, however, many lung cancer survi...