Genetics in Sarcoidosis and Its Burden as a Multisystem Disease [0.03%]
遗传学在 sarcoidosis 及其作为多系统疾病负担中的作用
Natalia V Rivera,Anders Eklund
Natalia V Rivera
Sarcoidosis is a complex, immune-mediated disease characterized by a broad spectrum of clinical and molecular phenotypes-often referred to as endophenotypes-some of which progress to chronic outcomes such as pulmonary fibrosis. Despite deca...
Critical Challenges: Respiratory Infections in Immunocompromised ICU Patients [0.03%]
免疫抑制ICU患者的呼吸道感染之关键挑战
Catia Cilloniz,Julio Ramirez
Catia Cilloniz
María Florencia Pilia,David Espejo-Castellanos,Christian Romero-Mesones et al.
María Florencia Pilia et al.
Severe asthma affects approximately 3-10% of the asthmatic population and is characterized by persistent symptoms and frequent exacerbations despite high-intensity therapy. Historically, glucocorticoids (GCs) have been the mainstay of treat...
Ashley Cattran,Dan Culver
Ashley Cattran
Sarcoidosis is an enigmatic, multi-system inflammatory disorder characterized by the formation of non-necrotizing granulomas in affected organs. Sarcoidosis may be self-limited or spontaneously resolve in up to two-thirds of individuals, bu...
Ninth Edition of the Tumor, Node, and Metastasis Classification of Lung Cancer [0.03%]
肺癌肿瘤、结节和转移分类第九版
Kwun M Fong,Gerry Olive,Henry M Marshall et al.
Kwun M Fong et al.
This paper reviews the development of the current edition (Ninth) of the Tumor, Node, and Metastasis (TNM) classification of lung cancer. This classification was proposed from the analyses of a global database of 124,581 patients diagnosed ...
Bridging Bench to the Bedside: The Imperative of Preclinical and Translational Research in Pulmonary Medicine [0.03%]
从实验室到病床：肺医学前期研究和转化研究的必要性
Elizabeth F Redente,Satish K Madala
Elizabeth F Redente
Mareye Voortman,Lisette Raasing,Jessica Burggraaff et al.
Mareye Voortman et al.
Sarcoidosis is a systemic inflammatory disorder of unknown cause, mainly affecting the lungs and lymph nodes. Symptoms are diverse and range from dyspnea and cough to fatigue, cognitive impairment, and pain. An important cause of pain in pa...
Riccardo Guglielmi,Antonio Campanella,Jesús Villar et al.
Riccardo Guglielmi et al.
Acute respiratory distress syndrome (ARDS) remains a heterogeneous and a major challenge disease process despite five decades of study. Emerging translational data delineate three overlapping phases: exudative, proliferative, and fibroproli...
Biomarkers in Sarcoidosis: From Traditional Markers to Precision Medicine [0.03%]
从传统的生物标志物到精准医疗 sarcoidosis中的生物标志物
Maria Belén Pascual,Juan Zapata,Daniel Ramos et al.
Maria Belén Pascual et al.
. Sarcoidosis remains a diagnostic and therapeutic challenge due to its heterogeneous clinical presentation and lack of pathognomonic features. Despite five decades of biomarker research, no single marker has achieved sufficient accuracy fo...
Jayleigh Lim,Niamh Boyle,Cormac McCarthy
Jayleigh Lim
Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterised by progressive accumulation of surfactant in pulmonary alveoli, resulting in hypoxemic respiratory insufficiency, and an increased risk of secondary infections and pulmon...