Mareye Voortman,Lisette Raasing,Jessica Burggraaff et al.
Mareye Voortman et al.
Sarcoidosis is a systemic inflammatory disorder of unknown cause, mainly affecting the lungs and lymph nodes. Symptoms are diverse and range from dyspnea and cough to fatigue, cognitive impairment, and pain. An important cause of pain in pa...
Riccardo Guglielmi,Antonio Campanella,Jesús Villar et al.
Riccardo Guglielmi et al.
Acute respiratory distress syndrome (ARDS) remains a heterogeneous and a major challenge disease process despite five decades of study. Emerging translational data delineate three overlapping phases: exudative, proliferative, and fibroproli...
Biomarkers in Sarcoidosis: From Traditional Markers to Precision Medicine [0.03%]
从传统的生物标志物到精准医疗 sarcoidosis中的生物标志物
Maria Belén Pascual,Juan Zapata,Daniel Ramos et al.
Maria Belén Pascual et al.
. Sarcoidosis remains a diagnostic and therapeutic challenge due to its heterogeneous clinical presentation and lack of pathognomonic features. Despite five decades of biomarker research, no single marker has achieved sufficient accuracy fo...
Jayleigh Lim,Niamh Boyle,Cormac McCarthy
Jayleigh Lim
Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterised by progressive accumulation of surfactant in pulmonary alveoli, resulting in hypoxemic respiratory insufficiency, and an increased risk of secondary infections and pulmon...
Spyros A Papiris,Maria Kallieri,Maurizio Zompatori et al.
Spyros A Papiris et al.
Autoimmune Pulmonary Alveolar Proteinosis (aPAP) is a rare disease characterized by abnormal accumulation of surfactant in alveoli. Pathogenetically, in aPAP the presence of granulocyte macrophage-colony stimulating factor (GM-CSF) autoanti...
Christen Vagts,Christian Ascoli,Jeffrey R Jacobson
Christen Vagts
Sarcoidosis is a granulomatous disease of unknown cause, triggered by an unidentified antigen. Although classically considered a T cell-mediated disorder with an IFN-γ signature driven by Th1, Th17, and Th17.1 cells, its pathogenesis refle...
M Patricia Rivera,Catherine R Sears
M Patricia Rivera
Pulmonary Alveolar Microlithiasis: A Review of a Rare Disease Through Rarely Discussed Perspectives [0.03%]
肺泡微结石症：罕见病的少见视角下的综述研究
Göksel Altınışık,Nilüfer Yiğit,Nazlı Çetin
Göksel Altınışık
Pulmonary alveolar microlithiasis (PAM) has been well characterized in terms of its description, genetic background, and diagnostic process for decades; however, no effective prevention or treatment has yet been established. PAM is classifi...
Genetics and social determinants of health as drivers of epidemiologic variation in sarcoidosis [0.03%]
遗传因素和社会决定因素在 sarcoidosis 流行病学差异中的驱动作用
John Odackal,Elliott Crouser,Michelle Sharp et al.
John Odackal et al.
Sarcoidosis is a disease with high morbidity that has variable epidemiology based on genetics and sociodemographic factors. The etiology of this variability remains incompletely understood. This narrative review describes how genetics, soci...
John Murray,Shane O&#x;Brien,Patrick Mitchell
John Murray
Diffuse Alveolar Hemorrhage (DAH) is a life-threatening clinical syndrome characterized by bleeding from the pulmonary microcirculation into alveolar spaces. It typicially presents with acute respiratory failure, anemia, and diffuse radiolo...