Inflammatory Response in Exacerbations of COPD: Clinical and Predictive Roles of C-Reactive Protein [0.03%]
C反应蛋白在慢性阻塞性肺疾病急性加重中的炎症作用及临床预测价值
Giulia Sartori,Alberto Fantin,Filippo Sartori et al.
Giulia Sartori et al.
Acute exacerbations of chronic obstructive pulmonary disease (ECOPD) are pivotal events that accelerate lung function decline, impair quality of life, and increase the risk of hospitalization and mortality. Beyond episodic airway deteriorat...
Jose Luis Lopez Campos,Jose Antonio Jimenez Ruiz,Esther Quintana-Gallego
Jose Luis Lopez Campos
COPD exacerbations represent the most common acute event and the one with the greatest medium- to long-term clinical and prognostic impact, acting as a key driver of functional decline, deterioration in quality of life, and a substantial sh...
Roberto Tonelli,Sofia Michelacci,Alessia Verduri et al.
Roberto Tonelli et al.
Acute exacerbations of chronic obstructive pulmonary disease (ECOPD) represent crucial events in the natural history of the disease. These are mainly characterized by abrupt worsening of respiratory symptoms, i.e. dyspnea, cough, sputum pro...
Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions [0.03%]
重症监护研究设计的局限性及对未来研究方向的建议
Guanfranco Umberto Meduri,Simone Lannini,Jim M Smit
Guanfranco Umberto Meduri
Glucocorticoid (GC) therapy has been a cornerstone of critical care; however, its full potential has been constrained by fixed-dose regimens and trial designs that predate current insights into the dynamic, phase-specific functions of gluco...
Pulmonary Infections in Patients Receiving Corticosteroids and Other Immunomodulators [0.03%]
接受皮质类固醇和其他免疫调节剂治疗患者的肺部感染
Emily S Hartman,Rodrigo Cavallazzi
Emily S Hartman
The prevalence of immunosuppression in the general population has been increasing over time due to a combination of factors, including advances in health care and the emergence of new therapies. Population-based studies show that approximat...
Monographic Issue on Glucocorticoid Therapy in Critical Illness and Respiratory Disease [0.03%]
重症和呼吸系统疾病糖皮质激素治疗专题研究
Guanfranco Umberto Meduri,Antoni Torres
Guanfranco Umberto Meduri
Pascalin Roy,Sara Shadchehr,Anne Gonzalez
Pascalin Roy
Lung cancer is the leading cause of cancer incidence and mortality worldwide. Pulmonologists play a central role in the timely, guideline-concordant diagnosis and staging of lung cancer. Minimally invasive procedures must also provide suffi...
Advanced pulmonary sarcoidosis [0.03%]
重症肺结节病
Paolo Spagnolo,Zehra Dhanani,Paolo Cameli et al.
Paolo Spagnolo et al.
In sarcoidosis, pulmonary manifestations are almost universal; however, their severity ranges from asymptomatic to respiratory failure and death. Approximately 20% of patients progress to advanced pulmonary sarcoidosis (APS), a disease phen...
Neurosarcoidosis in Critical Care, Internal and Pulmonary Medicine: A Practical Approach [0.03%]
重症监护、内科和肺科神经肉芽肿病：实用方法
Munther M Queisi,Carlos A Pardo
Munther M Queisi
Neurosarcoidosis is a rare but clinically significant manifestation of sarcoidosis, often presenting with diverse neurologic symptoms that can lead to permanent disability if left untreated. This review aims to provide internists, pulmonolo...
Top 7 Diagnostic Dilemmas in Cardiac Sarcoidosis: Lessons from Clinical Practice [0.03%]
心脏肉芽肿病诊断的七大难题：临床经验教训
Anjali A Wagle,Irena Kuzma,Nisha A Gilotra
Anjali A Wagle
Cardiac sarcoidosis (CS) is a potentially fatal but often underrecognized manifestation of systemic sarcoidosis. Its diagnosis remains a major clinical challenge due to nonspecific symptoms, overlapping features with other cardiac and genet...