Archana Bhaskaran,S M Hosseini-Moghaddam,Coleman Rotstein et al.
Archana Bhaskaran et al.
Fungal infections continue to produce morbidity and mortality in lung transplant recipients despite the widespread use of antifungal prophylaxis. There has been a decline in Candida infections but Aspergillus species predominate. Other mold...
Gregory I Snell,Miranda Paraskeva,Glen P Westall
Gregory I Snell
This article reviews recent developments in the selection, assessment, and management of the potential lung donor, which aim to increase donor organ use. The scarcity of suitable donor organs continues to limit lung transplantation, but the...
Neutrophilic reversible allograft dysfunction (NRAD) and restrictive allograft syndrome (RAS) [0.03%]
中性粒细胞介导的可逆性移植物功能障碍(NRAD)和限制性移植物综合征(RAS)
Stijn E Verleden,Elly Vandermeulen,David Ruttens et al.
Stijn E Verleden et al.
Lung transplantation is currently considered as an ultimate live-saving treatment for selected patients suffering from end-stage pulmonary disease. Long-term survival, however, is hampered by chronic rejection, or chronic lung allograft dys...
Bronchiolitis obliterans syndrome: the Achilles' heel of lung transplantation [0.03%]
支气管肺泡炎综合征：肺移植的阿喀琉斯之踵
S Samuel Weigt,Ariss DerHovanessian,W Dean Wallace et al.
S Samuel Weigt et al.
Lung transplantation is a therapeutic option for patients with end-stage pulmonary disorders. Unfortunately, chronic lung allograft dysfunction (CLAD), most commonly manifest as bronchiolitis obliterans syndrome (BOS), continues to be highl...
William McManigle,Elizabeth N Pavlisko,Tereza Martinu
William McManigle
Survival post-lung transplantation remains limited to ∼ 50% at 5 years, far below survival after other solid organ transplants. Allograft rejection is a major cause of this limited survival. At least a third of lung transplant recipients e...
Yoshikazu Suzuki,Edward Cantu,Jason D Christie
Yoshikazu Suzuki
Primary graft dysfunction (PGD) is a syndrome encompassing a spectrum of mild to severe lung injury that occurs within the first 72 hours after lung transplantation. PGD is characterized by pulmonary edema with diffuse alveolar damage that ...
Paul A Corris
Paul A Corris
Lung transplantation has become an excellent treatment option for patients with cystic fibrosis (CF) and bronchiectasis with very advanced lung disease. Despite the challenges that the CF patients present, survival is more favorable than th...
Rupal J Shah,Robert M Kotloff
Rupal J Shah
Chronic obstructive pulmonary disease (COPD) represents one of the most common indications for lung transplantation, accounting for approximately one third of all procedures performed worldwide to date. Despite this extensive experience, qu...
Lung transplantation for interstitial lung diseases and pulmonary hypertension [0.03%]
间质性肺病和肺动脉高压患者的肺移植手术
Jens Gottlieb
Jens Gottlieb
Lung transplantation (LTx) is an established therapeutic option for patients with various end-stage lung diseases. Presently the worldwide procedural frequency is ∼ 3,200 per year. Unfortunately, the shortage of donor organs leads to appro...
Pamela J McShane,Edward R Garrity Jr
Pamela J McShane
The number of donors falls short of the number of patients on the wait list for lung transplantation making it necessary to ration the available donor organs. The ideal allocation system is guided by ethical principles and scientifically ac...