Marc Humbert
Marc Humbert
Biomarkers of ALI/ARDS: pathogenesis, discovery, and relevance to clinical trials [0.03%]
急性肺损伤和急性呼吸窘迫综合征的生物标志物：发病机制、发现以及与临床试验的相关性
David R Janz,Lorraine B Ware
David R Janz
Despite the high incidence and poor prognosis of acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS), it remains challenging to identify patients who are at highest risk of developing these syndromes, differentiate th...
Cost and health care utilization in ARDS--different from other critical illness? [0.03%]
ARDS的费用和卫生保健利用情况与其他危重症不同吗？
Thomas Bice,Christopher E Cox,Shannon S Carson
Thomas Bice
Costs of care in the intensive care unit are a frequent target for concern in the current health care system. Utilization of critical care services in the United States is increasing and will continue to do so. Acute respiratory distress sy...
Lung-injured patients do not need a specialized rehabilitation program: ICUAW as a case study [0.03%]
肺损伤患者不需要专门的康复项目：以ICUAW为例
Margaret Herridge,Jane Batt,Claudia C Dos Santos et al.
Margaret Herridge et al.
An episode of critical illness is transformative. Patients suffer important new nerve, brain, and muscle injury. The spectrum of morbidity varies according to individual risks, but prevalent disabilities transcend diagnostic groupings. In t...
Maureen O Meade,Francois Lamontagne
Maureen O Meade
The evolution of scientific investigation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) is replete with examples of effective bench-to-bedside transitions, pioneering research methodology, and international colla...
Greg S Martin
Greg S Martin
Because acute lung injury (ALI) may arise from diverse and heterogeneous clinical insults, monitoring strategies for patients with ALI are heterogeneous as well. This review divides the monitoring strategies for ALI into three distinct phas...
Mashael Al-Hegelan,Neil R MacIntyre
Mashael Al-Hegelan
The overarching goal of positive pressure mechanical ventilation is to provide adequate gas exchange support while not causing harm. Indeed, positive pressure mechanical ventilators are only support technologies, not therapeutic technologie...
Treatment of acute lung injury: current and emerging pharmacological therapies [0.03%]
急性肺损伤的药物治疗：现状与展望
Rob Mac Sweeney,Mark Griffiths,Danny McAuley
Rob Mac Sweeney
As a syndrome of injurious pulmonary inflammation resulting in deranged respiratory physiology, acute lung injury affords numerous potential therapeutic targets. Two main pharmacological treatment strategies have arisen-the attempted inhibi...
Viral pathogens and acute lung injury: investigations inspired by the SARS epidemic and the 2009 H1N1 influenza pandemic [0.03%]
病毒病原与急性肺损伤：由SARS和2009年甲型H1N1流感大流行所引发的研究
Carolyn M Hendrickson,Michael A Matthay
Carolyn M Hendrickson
Acute viral pneumonia is an important cause of acute lung injury (ALI), although not enough is known about the exact incidence of viral infection in ALI. Polymerase chain reaction-based assays, direct fluorescent antigen (DFA) assays, and v...
Genetic heterogeneity and risk of acute respiratory distress syndrome [0.03%]
基因异质性与急性呼吸窘迫综合征的发病风险的关系
Nuala J Meyer,Jason D Christie
Nuala J Meyer
Genetic variation explains some of the observed heterogeneity in patients' risk for developing the acute respiratory distress syndrome (ARDS). Although the lack of extant family pedigrees for ARDS precludes an estimate of heritability of th...