Nonpharmacological Strategies to Improve Stability and Prevent Exacerbations of COPD [0.03%]
改善慢性阻塞性肺疾病(COPD)稳定性和预防急性加重的非药物策略
Michele Vitacca,Nicolino Ambrosino
Michele Vitacca
Exacerbations of chronic obstructive pulmonary disease (ECOPD) are the main cause of hospitalization, mortality, and progressive worsening in health-related quality of life (HRQL). Each ECOPD speeds functional decline, making these individu...
Microbiologic Diagnosis of Respiratory Infections in Critically Ill Immunocompromised Patients [0.03%]
重症免疫抑制患者呼吸道感染的微生物学诊断
Yupeng Liu,Chiagozie Pickens
Yupeng Liu
Critically ill, immunocompromised individuals are vulnerable to both common and uncommon etiologies of respiratory infection. Identifying the etiology of infection has therapeutic, prognostic, and public health implications. In some circums...
Giulia Panzuti,Tommaso Zanaboni,Lara Pisani
Giulia Panzuti
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are acute events characterized by rapid worsening of dyspnea, cough, and sputum production, often leading to gas exchange impairment, ventilatory failure, and hospitaliz...
Alberto Fantin,Nadia Castaldo,Giulia Sartori et al.
Alberto Fantin et al.
Acute exacerbations of chronic obstructive pulmonary disease (ECOPD) represent major inflection points in the natural history of the disease, driving accelerated functional decline, reduced autonomy, and increased cardiovascular and mortali...
Inflammatory Response in Exacerbations of COPD: Clinical and Predictive Roles of C-Reactive Protein [0.03%]
C反应蛋白在慢性阻塞性肺疾病急性加重中的炎症作用及临床预测价值
Giulia Sartori,Alberto Fantin,Filippo Sartori et al.
Giulia Sartori et al.
Acute exacerbations of chronic obstructive pulmonary disease (ECOPD) are pivotal events that accelerate lung function decline, impair quality of life, and increase the risk of hospitalization and mortality. Beyond episodic airway deteriorat...
Jose Luis Lopez Campos,Jose Antonio Jimenez Ruiz,Esther Quintana-Gallego
Jose Luis Lopez Campos
COPD exacerbations represent the most common acute event and the one with the greatest medium- to long-term clinical and prognostic impact, acting as a key driver of functional decline, deterioration in quality of life, and a substantial sh...
Roberto Tonelli,Sofia Michelacci,Alessia Verduri et al.
Roberto Tonelli et al.
Acute exacerbations of chronic obstructive pulmonary disease (ECOPD) represent crucial events in the natural history of the disease. These are mainly characterized by abrupt worsening of respiratory symptoms, i.e. dyspnea, cough, sputum pro...
Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions [0.03%]
重症监护研究设计的局限性及对未来研究方向的建议
Guanfranco Umberto Meduri,Simone Lannini,Jim M Smit
Guanfranco Umberto Meduri
Glucocorticoid (GC) therapy has been a cornerstone of critical care; however, its full potential has been constrained by fixed-dose regimens and trial designs that predate current insights into the dynamic, phase-specific functions of gluco...
Pulmonary Infections in Patients Receiving Corticosteroids and Other Immunomodulators [0.03%]
接受皮质类固醇和其他免疫调节剂治疗患者的肺部感染
Emily S Hartman,Rodrigo Cavallazzi
Emily S Hartman
The prevalence of immunosuppression in the general population has been increasing over time due to a combination of factors, including advances in health care and the emergence of new therapies. Population-based studies show that approximat...
Monographic Issue on Glucocorticoid Therapy in Critical Illness and Respiratory Disease [0.03%]
重症和呼吸系统疾病糖皮质激素治疗专题研究
Guanfranco Umberto Meduri,Antoni Torres
Guanfranco Umberto Meduri