The autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy or autoimmune polyglandular syndrome type 1 [0.03%]
自身免疫性多内分泌病-念珠菌病- ectodermal异常综合征或多内分泌腺体综合症1型
Tim O Lankisch,Elmar Jaeckel,Christian P Strassburg
Tim O Lankisch
Autoimmune polyglandular syndromes are rare autoimmune endocrinopathies that are associated with nonendocrine autoimmunopathies. Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), also named autoimmune polyglandular sy...
Giorgina Mieli-Vergani,Diego Vergani
Giorgina Mieli-Vergani
Autoimmune hepatitis (AIH) is characterized by inflammatory liver histology, circulating non-organ-specific autoantibodies, and increased levels of immunoglobulin (Ig) G in the absence of a known etiology. Two types of childhood AIH are rec...
Autoimmune hepatitis and liver transplantation: indications, results, and management of recurrent disease [0.03%]
自身免疫性肝炎和肝脏移植：适应证、结果及复发性疾病的处理方法
Dhiraj Tripathi,James Neuberger
Dhiraj Tripathi
For those with autoimmune hepatitis (AIH), indications for liver transplantation include end-stage liver failure (as suggested by a MELD score >16), the onset of liver cancer, intractable symptoms that make the patient's life intolerable, a...
Christian P Strassburg,Michael P Manns
Christian P Strassburg
First described in 1950, autoimmune hepatitis (AIH) was the first chronic liver disease with a favorable response to drug therapy and a dismal prognosis when left untreated. In the decades since the first treatment studies, the basic strate...
Urs Christen,Edith Hintermann,Elmar Jaeckel
Urs Christen
Autoimmune hepatitis (AIH) is often diagnosed late in the disease course and usually requires lifelong immunosuppressive therapy. Unfortunately, the etiology of the disease and the mechanisms leading to the autoimmune destruction of the liv...
Scoring systems for the diagnosis of autoimmune hepatitis: past, present, and future [0.03%]
自身免疫性肝炎诊断评分系统：过去、现在和未来
Christiane Wiegard,Christoph Schramm,Ansgar W Lohse
Christiane Wiegard
The diagnosis of autoimmune hepatitis (AIH) can be challenging due to the variable clinical and laboratory findings. The original diagnostic criteria published in 1993 by the International Autoimmune Hepatitis Group (IAIHG) were revised in ...
Dimitrios P Bogdanos,Giorgina Mieli-Vergani,Diego Vergani
Dimitrios P Bogdanos
Autoantibody detection assists in the diagnosis and allows differentiation of autoimmune hepatitis (AIH) type 1 (AIH-1), characterized by antinuclear antibody (ANA) and/or smooth muscle antibody (SMA), and type 2 (AIH-2), distinguished by t...
Autoimmune hepatitis [0.03%]
自身免疫性肝炎
Michael P Manns,Diego Vergani
Michael P Manns
Patient with hepatitis B and alcoholic liver disease before and after liver transplantation [0.03%]
肝移植前後的一名乙型肝炎和酒精性肝病患者的病例
Stephen C Ward,Charissa Y Chang,Lan Peng et al.
Stephen C Ward et al.
We present the case of a patient with hepatitis B virus infection and alcohol use (30 g/day by self-report) who developed cirrhosis and proceeded to liver transplantation at age 49. The explanted liver showed cirrhosis with evidence of burn...
Iain H McKillop,Laura W Schrum
Iain H McKillop
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world and contributes significantly to cancer-related morbidity and mortality. Chronic alcohol consumption has long been associated with progressive liver dise...