Manasi Kotulkar,Diego Paine-Cabrera,Udayan Apte
Manasi Kotulkar
Liver cancer is the sixth most common cancer and the fourth leading cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and the incidence of HCC is on the rise. Liver cancers i...
Corrigendum: Liver Transplantation for Hepatocellular Carcinoma: A Narrative Review and A Glimpse into The Future [0.03%]
肝细胞癌肝脏移植的补遗：综述及未来展望
Hao Liu,Vrishketan Sethi,Xingjie Li et al.
Hao Liu et al.
Published Erratum
Seminars in liver disease. 2024 Feb;44(1):e1-e3. DOI:10.1055/s-0044-1787737 2024
Inflammation in Steatotic Liver Diseases: Pathogenesis and Therapeutic Targets [0.03%]
脂肪性肝病的炎症：发病机制和治疗靶点
Shengying Qian,Xiaolin Wang,Yingfen Chen et al.
Shengying Qian et al.
Alcohol-related liver disease (ALD) and metabolic dysfunction-associated steatotic liver disease (MASLD), two main types of steatotic liver disease (SLDs), are characterized by a wide spectrum of several different liver disorders, including...
Overcoming Resistance to Immune Checkpoint Blockade in Liver Cancer with Combination Therapy: Stronger Together? [0.03%]
联合治疗克服肝癌免疫检查点抑制抵抗：1+1＞2？
Wiebke Werner,Maria Kuzminskaya,Isabella Lurje et al.
Wiebke Werner et al.
Primary liver cancer, represented mainly by hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (CCA), is one of the most common and deadliest tumors worldwide. While surgical resection or liver transplantation are the best o...
This Is What Metabolic Dysfunction-Associated Steatotic Liver Disease Looks Like: Potential of a Multiparametric MRI Protocol [0.03%]
代谢功能紊乱相关性脂肪肝的MRI影像特征：多参数MRI检查的潜力
Anja M Fischer,Nazim Lechea,Harvey O Coxson
Anja M Fischer
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent condition with a broad spectrum defined by liver biopsy. This gold standard method evaluates three features: steatosis, activity (ballooning and lobular inflamm...
Heterogeneity in Liver Cancer Immune Microenvironment: Emerging Single-Cell and Spatial Perspectives [0.03%]
肝癌免疫微环境的异质性：单细胞和空间视角的新进展
Caiyi Cherry Li,Meng Liu,Hsin-Pei Lee et al.
Caiyi Cherry Li et al.
Primary liver cancer is a solid malignancy with a high mortality rate. The success of immunotherapy has shown great promise in improving patient care and highlights a crucial need to understand the complexity of the liver tumor immune micro...
Oluwashanu Balogun,Kari Nejak-Bowen
Oluwashanu Balogun
Hepatic porphyrias are a group of metabolic disorders that are characterized by overproduction and accumulation of porphyrin precursors in the liver. These porphyrins cause neurologic symptoms as well as cutaneous photosensitivity, and in s...
Hepatotoxicity of Antibiotics and Antifungals and Their Safe Use in Hepatic Impairment [0.03%]
抗生素和抗真菌药物的肝毒性及其在肝功能障碍中的安全使用
J Ma,E S Björnsson,N Chalasani
J Ma
Idiosyncratic drug-induced liver injury (DILI) is a rare and unpredictable form of hepatotoxicity. While its clinical course is usually benign, cases leading to liver transplantation or death can occur. Based on modern prospective registrie...
Statins in Chronic Liver Disease: Review of the Literature and Future Role [0.03%]
他汀类药物在慢性肝病中的应用：文献回顾及未来展望
Nguyen Pham,Jihane N Benhammou
Nguyen Pham
Chronic liver disease (CLD) is a major contributor to global mortality, morbidity, and healthcare burden. Progress in pharmacotherapeutic for CLD management is lagging given its impact on the global population. While statins are indicated f...
Steven L Flamm,Alessandra Mangia
Steven L Flamm
Although therapy with direct-acting antiviral (DAA) agents achieves high hepatitis C virus (HCV) cure rates and is forgiving of missed doses, certain patient populations, such as people who inject drugs (PWID), are often denied therapy beca...