R Prasida Holla,Imran Ahmad,Zulfazal Ahmad et al.
R Prasida Holla et al.
Hepatitis E virus (HEV) is the causative agent of hepatitis E. It is a nonenveloped virus with a ∼7.2 kilobases positive-stranded RNA genome. The molecular virology of HEV is getting better understood with the development of replicons and ...
Kris Krawczynski
Kris Krawczynski
Multidisciplinary management of hepatocellular carcinoma: where are we today? [0.03%]
肝细胞癌的多学科综合治疗现状如何？
Jorge A Marrero
Jorge A Marrero
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide, and the incidence of HCC continues to rise. Improved understanding of risk factors for HCC has allowed the development of more effective preven...
Ghassan Abou-Alfa,Massimo Colombo
Ghassan Abou-Alfa
Several advances in recent years have led to improved surveillance, diagnostic, and treatment options for hepatocellular carcinoma (HCC). Despite these advances, care for this malignancy remains suboptimal, in part because of poor adherence...
Richard S Finn
Richard S Finn
Treatment of advanced-stage hepatocellular carcinoma (HCC) remains a challenge because of the complex nature of the disease and the lack of available therapies. The antiangiogenic multikinase inhibitor sorafenib is the first therapy to demo...
Ghassan Abou-Alfa
Ghassan Abou-Alfa
Cholangiolocellular carcinoma in a pediatric patient with small duct sclerosing cholangitis: a case report [0.03%]
小管硬化性胆管炎患儿并发胆管细胞肝癌一例报告
Joanne Lai,Bashir Taouli,Kishore R Iyer et al.
Joanne Lai et al.
Although guidelines exist for routine screening for malignancy in adults with primary sclerosing cholangitis, no imaging guidelines exist for the pediatric population. Cholangiolocellular carcinoma is a rare malignant liver tumor that has b...
Heterogeneity of patients with intermediate (BCLC B) Hepatocellular Carcinoma: proposal for a subclassification to facilitate treatment decisions [0.03%]
巴塞罗那分期B期肝细胞癌患者的异质性：制定亚分类以利于治疗决策的建议
Luigi Bolondi,Andrew Burroughs,Jean-François Dufour et al.
Luigi Bolondi et al.
The intermediate stage of hepatocellular carcinoma (HCC) comprises a highly heterogeneous patient population and therefore poses unique challenges for therapeutic management, different from the early and advanced stages. Patients classified...
Prevention and treatment of intestinal failure-associated liver disease in children [0.03%]
儿童肠功能衰竭相关性肝病的预防和治疗
Bram P Raphael,Christopher Duggan
Bram P Raphael
Intestinal failure-associated liver disease (IFALD), a serious complication occurring in infants, children, and adults exposed to long-term parenteral nutrition (PN), causes a wide-spectrum of disease, ranging from cholestasis and steatosis...
Steven Lobritto,Tomoaki Kato,Jean Emond
Steven Lobritto
The disparity between the number of available deceased liver donors and the number of patients awaiting transplantation continues to be an ongoing issue predisposing to death on the liver transplant waiting list. Deceased donor shortage str...