Jean C Emond,Michael D Kluger
Jean C Emond
Telangiectatic hyperplastic nodule associated with vascular malformation in a patient with chronic hepatitis B: radiologic and pathologic features [0.03%]
慢性乙型肝炎患者血管畸形相关性 telangiectatic 型增生结节的影像及病理特征
Gonzalo Carrasco,Cecilia Besa,Sara C Lewis et al.
Gonzalo Carrasco et al.
Recognizing hepatocellular nodules that cannot be classified as typical for hepatocellular carcinoma, hepatocellular adenoma, or focal nodular hyperplasia is important, especially in a patient with high risk for hepatocellular carcinoma. Th...
Daniel Shouval,Oren Shibolet
Daniel Shouval
Hepatitis B virus (HBV) reactivation following immunosuppression is defined by an abrupt rise in HBV replication followed by laboratory signs of hepatocellular injury in a "silent" hepatitis B surface antigen (HBsAg) carrier. Reactivation c...
Does antiviral therapy for chronic hepatitis B reduce the risk of hepatocellular carcinoma? [0.03%]
抗病毒治疗能否降低慢性乙肝患者肝细胞癌的风险？
Mahmoud Abu-Amara,Jordan J Feld
Mahmoud Abu-Amara
Chronic hepatitis B infection (CHB) is common and can lead to serious consequences including liver cirrhosis, failure, and hepatocellular carcinoma (HCC). The hepatitis B virus (HBV) has a simple genome, but a complex lifecycle that include...
Francesca Guerrieri,Laura Belloni,Natalia Pediconi et al.
Francesca Guerrieri et al.
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through direct and indirect mechanisms. HBV-DNA integration into the host genome occurs at early steps of clonal tumor expansion and induces both genomic inst...
Calvin Q Pan,Hannah M Lee
Calvin Q Pan
The management of chronic hepatitis B (CHB) during pregnancy remains a challenge and involves various aspects of maternal-fetal care. Despite the standard immunoprophylaxis, a significant portion of infants born to highly viremic mothers re...
Simon P Fletcher,William E Delaney th
Simon P Fletcher
Chronic hepatitis B virus (CHB) is managed effectively with either nucleoside/nucleotide-based or interferon-based therapies. However, most patients receiving these therapies do not establish long-term, durable control of infection after tr...
Vincent Wai-Sun Wong,Henry Lik-Yuen Chan
Vincent Wai-Sun Wong
In the past two decades, there have been major developments in the treatment of chronic hepatitis B. Peginterferon can be given conveniently with weekly dosing, and its effect on hepatitis B e antigen seroconversion is highly durable. Howev...
Advances in the molecular diagnosis of hepatitis B infection: providing insight into the next generation of disease [0.03%]
乙型肝炎感染分子诊断的研究进展：透视下一代疾病学说
Julianne Bayliss,Tin Nguyen,C Rinaldi A Lesmana et al.
Julianne Bayliss et al.
Hepatitis B virus (HBV) infection continues to represent a significant health threat, affecting over 400 million people worldwide. Historically, the diagnosis and treatment of chronic hepatitis B (CHB) relied in detection of the hepatitis B...
Dieter Glebe,Corinna M Bremer
Dieter Glebe
Hepatitis B virus (HBV) is one of the smallest enveloped DNA viruses and the prototype member of the family of Hepadnaviridae that causes acute and chronic infections of mammals (including human) and birds. HBV has evolved an extreme adapta...