Moira B Hilscher,Jonathan Johnson
Moira B Hilscher
Fontan associated liver disease (FALD) occurs in all patients who have undergone Fontan palliative repair for functional single ventricle congenital heart defects. While liver fibrosis is universal in patients who have undergone Fontan repa...
Role of Intestinal Barrier Disruption to Acute-on-Chronic Liver Failure [0.03%]
肠道屏障功能破坏在急性加重的慢性肝功能不全中的作用
Julian Pohl,Dimitrios Aretakis,Frank Tacke et al.
Julian Pohl et al.
Acute-on-chronic liver failure (ACLF) is a severe condition in patients with decompensated liver cirrhosis, marked by high short-term mortality. Recent experimental and clinical evidence has linked intestinal dysfunction to both the initiat...
Laura Sererols-Viñas,Gemma Garcia-Vicién,Paloma Ruiz-Blázquez et al.
Laura Sererols-Viñas et al.
Hepatic stellate cells (HSCs) are the liver's pericytes, and play key roles in liver homeostasis, regeneration, fibrosis and cancer. Upon injury, HSCs activate and are the main origin of myofibroblasts and cancer associated fibroblasts (CAF...
PATHOGENESIS AND MANAGEMENT OF INTESTINAL FAILURE-ASSOCIATED LIVER DISEASE [0.03%]
肠功能衰竭相关肝病的发病机制和处理方法
Sasha-Jane Abi-Aad,Mark Lovell,Racha Khalaf et al.
Sasha-Jane Abi-Aad et al.
Long-term parenteral nutrition (PN) has considerably improved the management of intestinal failure (IF) in children and adults, particularly those with short bowel syndrome; however, it carries a significant risk of hepatotoxicity, specific...
Preface (Introduction) [0.03%]
前言（介绍）
Ashwani K Singal
Ashwani K Singal
Not applicable. Thieme. All rights reserved.
Jordi Gratacós-Ginès,Edilmar Alvarado-Tapias,David Marti-Aguado et al.
Jordi Gratacós-Ginès et al.
Early forms of alcohol-associated liver disease (ALD) include different stages in the progression of compensated liver disease ranging from steatosis to steatohepatitis and fibrosis. ALD has been classically diagnosed at advanced stages mor...
Jie-Wen Zhang,Nan Zhang,Yi Lyu et al.
Jie-Wen Zhang et al.
The liver is a sexually dimorphic organ. Sex differences in prevalence, progression, prognosis and treatment do prevail in most liver diseases, and the mechanism of how liver diseases act differently among male versus female patients have n...
Current Concepts in Fluid Resuscitation and Vasopressor Use in Cirrhosis [0.03%]
当前肝硬化患者液体复苏与血管活性药物使用的概念
Madhumita Premkumar,Kamal Kajal,Pankaj Gupta et al.
Madhumita Premkumar et al.
Critically ill patients with cirrhosis and liver failure not uncommonly have hypotension due to multifactorial reasons, that include hyperdynamic state with increased cardiac index, low systemic vascular resistance due to portal hypertensio...
Qixiang Wu,Dashuai Yang,Chixiang Liu et al.
Qixiang Wu et al.
Alcohol-associated liver disease (ALD), primarily caused by chronic excessive alcohol consumption, is a leading cause of chronic liver disease worldwide. ALD includes alcohol-associated steatotic liver, alcohol-associated hepatitis (AH), fi...
Alexander M Washington,Enis Kostallari
Alexander M Washington
Progression of liver disease is dependent on intercellular signaling, including those mediated by extracellular vesicles (EVs). Within these EVs, microRNAs (miRNAs) are packaged to selectively silence gene expression in recipient cells for ...