Alleviating effects of Nigella sativa supplements on biomarkers of inflammation and oxidative stress: Results from an umbrella meta-analysis [0.03%]
胡芦巴补充剂对炎症和氧化应激生物标志物的缓解作用：伞形META分析结果
Xinyu Lan,Yongliang Xia
Xinyu Lan
Several meta-analyses have examined the effect of Nigella sativa (N. Sativa) supplementation on inflammatory and oxidative markers, with conflicting results. So, the current study evaluated the effect of N. Sativa on some oxidative and infl...
A high seizure burden increases brain concentrations of specialized pro-resolving mediators in the Scn1a+/- mouse model of Dravet syndrome [0.03%]
高发作负担可增加Scn1a+/-小鼠模型大脑中专门的消解介质浓度
Ka Lai Yip,Cilla Zhou,Lyndsey L Anderson et al.
Ka Lai Yip et al.
Objective: Dravet syndrome is a severe, intractable epilepsy in which 80 % of patients have a de novo mutation in the gene SCN1A. We recently reported that a high seizure burden increased hippocampal concentrations of an ...
Inflammatory protein levels in asthmatic bronchitis: A study in the Duhok population, Iraq [0.03%]
伊拉克杜赫OK地区哮喘性支气管炎的炎症蛋白水平研究
Omar A M Al-Habib,Hamdia Yousif Issa,Taner Dastan et al.
Omar A M Al-Habib et al.
Objectives: This study aims to determine the levels of TNF-α, IGF-1, IL-6, and IL-10 protein in blood samples and their potential link to bronchitis-asthma diseases in the Iraq Duhok population, highlighting the prevalen...
Effect of soluble fiber supplementation on lipid parameters in subjects with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials [0.03%]
可溶性膳食纤维补充剂对2型糖尿病患者血脂参数影响的系统评价和meta分析
Jitendra Gupta,Munthar Kadhim Abosaoda,Madhu Shukla et al.
Jitendra Gupta et al.
Background: There is no consensus in the existing literature regarding the effect of soluble fiber on the lipid profile of patients with type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis of randomi...
TFAP2A activates CTHRC1 to influence the migration of lung adenocarcinoma cells by modulating fatty acid metabolism [0.03%]
转录因子TFAP2A通过调节脂肪酸代谢激活CTHRC1促进肺腺癌细胞迁移
Xiaodong Zheng,Junzheng Zhou,Shiwei Nie et al.
Xiaodong Zheng et al.
Background: Tumor metastasis is the main cause of death in lung adenocarcinoma (LAC) patients. It is known that the collagen triple helix repeats containing 1 (CTHRC1) protein is implicated in tissue remodeling and is tig...
Protective role of Yougui Yin in experimental knee osteoarthritis: From the perspective of macrophage polarization [0.03%]
育癸饮对实验性膝骨关节炎保护作用的巨噬细胞极化角度研究
Zhongqing Wu,Kanna Xu,Minchang Chen et al.
Zhongqing Wu et al.
Knee osteoarthritis (KOA) refers to a prevalent musculoskeletal disorder, frequently complicated by substantial pain and physical disability. Yougui Yin (YGY) is a classic Chinese herbal mixture which has demonstrated potential in treating ...
The effect of vitamin D on the lipid profile in individuals with overweight or obesity: A meta-analysis and systematic review of randomized controlled trials [0.03%]
维生素D对超重或肥胖人群血脂谱的影响：基于随机对照试验的系统综述和meta分析研究
Kehao Yu,Wentao Song,Xinyu Tu et al.
Kehao Yu et al.
Background and aim: Previous studies have reported on the relationship between vitamin D and the lipid profile in individuals with obesity or overweight, but results have been inconsistent. Hence, we conducted this meta-a...
Potassium channels mediate nitric oxide-induced vasorelaxation in arteries supplying colon cancer [0.03%]
钾通道介导一氧化氮引起的结肠癌供血动脉舒张作用
Kamaran H Mohammed,Sardar H Arif,Lina N Adam et al.
Kamaran H Mohammed et al.
Introduction: Aberrant vascular function and cancer growth are closely related, with nitric oxide (NO) being a key factor in vascular tone regulation. This study provides Novel insights into the distinctive mechanisms und...
Rosmarinic acid alleviates the cardiac abnormalities in high fat diet induced hypercholesterolemic rats [0.03%]
岩白菜酸缓解高脂饮食诱导的hypercholesterolemic大鼠心脏异常现象
Sundaram,R MuthuK
Sundaram
Hyperlipidemia is a well-known risk factor for atherosclerosis and subsequent atherosclerotic cardiovascular diseases that are associated with high morbidity and mortality in obese and diabetic patients worldwide. The current study looked o...
Cigarette smoke-induced attenuation of the prostaglandin transporter SLCO2A1 expression through aryl hydrocarbon receptor [0.03%]
通过芳烃受体介导的前列腺素转运蛋白SLCO2A1表达抑制参与吸烟所致慢性肺部疾病恶化
Melody N Shumba,Yoshinobu Nakamura,Takeo Nakanishi
Melody N Shumba
SLCO2A1 is a prostaglandin transporter and contributes to regulating local concentration of an inflammatory mediator, PGE2. Since we previously found that cigarette smoke extracts (CSE) reduced Slco2a1 mRNA expression in rat alveolar epithe...