Expression and putative biological roles of lipoxygenases and leukotriene receptors in leukemia and lymphoma [0.03%]
脂氧合酶和白三烯受体在白血病和淋巴瘤中的表达及生物学作用的初步研究
Hans-Erik Claesson,Jan Sjöberg,Dawei Xu et al.
Hans-Erik Claesson et al.
This mini-review addresses lipoxygenases and receptors for leukotrienes in hematological malignancies. Potential novel biomarkers and drug targets in leukemia and B-cell lymphoma are discussed. ...
Plaat1l1 controls feeding induced NAPE biosynthesis and contributes to energy balance regulation in zebrafish [0.03%]
Plaat1l1控制喂食诱导的NAPE生物合成并参与斑马鱼能量平衡调节
Zahra Mashhadi,Linlin Yin,Noura S Dosoky et al.
Zahra Mashhadi et al.
Dysregulation of energy balance leading to obesity is a significant risk factor for cardiometabolic diseases such as diabetes, non-alcoholic fatty liver disease and atherosclerosis. In rodents and several other vertebrates, feeding has been...
Effects of flaxseed supplementation on inflammatory biomarkers: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials [0.03%]
亚麻籽补充剂对炎症生物标志物的影响：一项基于GRADE系统的荟萃分析
Vali Musazadeh,Reza Morovatshoar,Zeynab Kavyani et al.
Vali Musazadeh et al.
Several studies reported the benefits of flaxseed on inflammatory biomarkers, while others reported conflicting findings. Thus, the aim of this meta-analysis was to assess the impacts of flaxseed on inflammatory biomarkers in adults. Databa...
2-(3-(Chloromethyl)benzoyloxy)benzoic Acid reduces prostaglandin E-2 concentration, NOX2 and NFKB expression, ROS production, and COX-2 expression in lipopolysaccharide-induced mice [0.03%]
2-(3-（氯甲基）苯甲酰氧基)苯甲酸可降低脂多糖诱导型小鼠中前列腺素E_2浓度、NOX2和NFKB表达、ROS生成以及COX-2表达水平
Yudy Tjahjono,Caroline,Kuncoro Foe et al.
Yudy Tjahjono et al.
Introduction: Inflammation is a fundamental response to various insults, including microbial invasion and tissue injury. While aspirin (ASA) has been widely used for its anti-inflammatory properties, its adverse effects a...
Amy K Stark,John S Penn
Amy K Stark
The vasculature of the retina is exposed to systemic and local factors that have the capacity to induce several retinal vascular diseases, each of which may lead to vision loss. Prostaglandin signaling has arisen as a potential therapeutic ...
GOLPH3 knockdown alleviates the inflammation and apoptosis in lipopolysaccharide-induced acute lung injury by inhibiting Golgi stress mediated autophagy [0.03%]
GOLPH3敲低通过抑制高尔基体应激介导的自噬缓解脂多糖诱导的大鼠急性肺损伤炎症和细胞凋亡
Yanru Wang,Xiaoxia Li,Qin Zhou et al.
Yanru Wang et al.
Pneumonia, an acute inflammatory lesion of the lung, is the leading cause of death in children aged < 5 years. We aimed to study the function and mechanism of Golgi phosphoprotein 3 (GOLPH3) in infantile pneumonia. Lipopolysaccharide (LPS)-...
The effects of curcumin supplementation on biomarkers of inflammation, oxidative stress, and endothelial function: A meta-analysis of meta-analyses [0.03%]
姜黄素补充对炎症、氧化应激和内皮细胞功能生物标志物的影响：meta分析的荟萃分析
Zeynab Kavyani,Kianoosh Najafi,Navid Naghsh et al.
Zeynab Kavyani et al.
Numerous interventional studies have revealed the beneficial impact of curcumin supplementation on inflammation, oxidative stress, and endothelial function biomarkers, but the findings are still inconsistent. Thus, this study was conducted ...
Sesame oil downregulates the expression of ADAMTS-4 in high-fat diet-induced atherosclerosis [0.03%]
芝麻油下调高脂饮食诱导的动脉粥样硬化ADAMTS-4的表达
S S Aswani,N S Aparna,Mithra S Mohan et al.
S S Aswani et al.
Atherosclerosis is a chronic inflammatory disease forming plaques in medium and large-sized arteries. ADAMTS-4 (a disintegrin and metalloproteinase with thrombospondin motifs-4) is an extracellular-matrix remodelling enzyme involved in the ...
Interference with GPR4 inactivates NLRP3 inflammasome signaling by inhibiting LPAR1 expression to ameliorate oxygen-glucose deprivation/reoxygenation-induced inflammation and apoptosis of cardiomyocytes [0.03%]
干扰GPR4通过抑制LPAR1表达来抑制NLRP3炎性小体信号传导，以减轻心肌细胞缺氧葡萄糖剥夺/复氧诱导的炎症和凋亡
Hanlong He,Huiren Su,Xinjian Chen et al.
Hanlong He et al.
Myocardial ischemia/reperfusion (MI/R) injury is a detrimental disease with high mortality worldwide. We aimed to explore the role of G protein-coupled receptor 4 (GPR4) and lysophosphatidic acid receptor 1 (LPAR1) in MI/R injury in vitro. ...
Novel anti-cancer effect of 2-arachidonoylglycerol via processing body formation in HCA-7 human colon cancer cells [0.03%]
新型抗癌作用：2-花生四烯酸甘油通过HCA-7人类结肠癌细胞的处理体形成发挥作用
Takaya Misao,Keijo Fukushima,Hiromichi Fujino
Takaya Misao
The endocannabinoid 2-arachidonoylglycerol (2-AG) has been reported to exhibit anticancer effects, including against colorectal cancer (CRC); however, the detailed mechanisms have not been clarified. Herein, we demonstrated that 2-AG suppre...