Diagnostic value of galactomannan in tracheobronchial aspirate for Aspergillus infection in lung transplant recipients (the GALACTBAS study) [0.03%]
Arnau Monforte,Maria Teresa Martín-Gómez,Cristina Berastegui et al.
Arnau Monforte et al.
Lung transplant recipients (LTR) are highly susceptible to Aspergillus infection (AI), but diagnosis may be limited by the invasiveness of bronchoalveolar lavage fluid (BALF) collection. Proximal airway samples may provide a less invasive a...
Photo Quiz: An uncommon gram-negative pathogen in a splenectomized child with sickle cell disease [0.03%]
Jessy Zenon,Hosam Dawoud,Yasmine Benhadid-Brahmi et al.
Jessy Zenon et al.
Recurrent cross-reactivity between Candida tropicalis and Candida parapsilosis on the BIOFIRE FilmArray Blood Culture Identification 2 panel [0.03%]
Emily Puumala,Ryan W Stevens,Nancy L Wengenack
Emily Puumala
Andrew Walkty,Markus Stein,Heather Adam et al.
Andrew Walkty et al.
Cytokine and chemokine profiles linked to early severity of scrub typhus: multicenter validation of soluble PD-L1 [0.03%]
Dachuan Lin,Gaoyu Wang,Liyuan Zhang et al.
Dachuan Lin et al.
Early identification of patients at risk of developing severe disease remains a clinical challenge for scrub typhus. We aimed to identify serum cytokine profiles associated with disease severity and validate potential biomarkers for early r...
Regional-local urinary antibiograms for long-term care homes: a population-wide cross-sectional study [0.03%]
Bradley J Langford,Kevin A Brown,Sarah Swayze et al.
Bradley J Langford et al.
Antibiograms are challenging to construct in long-term care (LTC) homes in part due to low isolate counts and limited precision. Regional-local antibiograms offer a potential solution by using partial pooling, combining data from both the h...
MethylSense: high accuracy machine learning-based diagnostics for Aspergillus fumigatus infection in chickens using host cell-free DNA methylation and Nanopore sequencing [0.03%]
Markus Hodal Drag,Christina Hvilsom,Louise Ladefoged Poulsen et al.
Markus Hodal Drag et al.
Avian aspergillosis, caused by Aspergillus fumigatus (Af), lacks sensitive antemortem diagnostics. Existing microbial cell-free DNA (cfDNA) tests are prone to contamination and require a high pathogen load. We hypothesized that infection-in...
Diagnostic performance of β-(1→3)-D-glucan, two Candida antigen, and five anti- Candida antibody assays in ICU patients with sepsis and high risk for invasive candidiasis: a secondary endpoint of the CandiSep randomized clinical trial [0.03%]
Lea Standl,Timo Huber,Frank Bloos et al.
Lea Standl et al.
Invasive Candida infection (ICI) is the most common fungal infection in critically ill patients. This study analyzed the performance of various biomarkers in sera from the CandiSep trial, a randomized, multicenter trial including 342 sepsis...
Photo Quiz: Brown, thick-walled cells with evident septation in a purulent sample from a mason [0.03%]
Xiujiao Xia,Zehu Liu
Xiujiao Xia
Test performance of a commercial cryptococcal antigen lateral flow assay: a retrospective and prospective study at five Canadian sites [0.03%]
一项在加拿大五家医疗机构进行的商业曲霉抗原检测试剂条检测性能的回顾性和前瞻性研究
Catherine A Hogan,LingHui David Su,Jonathan Laley et al.
Catherine A Hogan et al.
Cryptococcal antigen (CrAg) lateral flow assay (LFA) enables the rapid and sensitive detection of cryptococcal infection. The FungiXpert CrAg LFA is a Health Canada-licensed product that currently lacks evaluation in the North American sett...