Poloxamer dilution as an on-demand alternative to agar dilution-based antimicrobial susceptibility testing [0.03%]
聚氧乙烯嵌段共聚物稀释法作为琼脂稀释法定量抗菌药物敏感性的即需型替代方法
Matthew T J Uy,Andrea Kirmaier,Lindsey M Rudtner et al.
Matthew T J Uy et al.
Agar dilution is a reference susceptibility testing method uniquely or preferentially recommended for certain antimicrobials. However, the effort required to pour individual agar plates spanning a doubling dilution range precludes its pract...
Etiologies of community-acquired febrile illness identified by TaqMan Array Card qPCR on blood samples: a systematic review and meta-analysis [0.03%]
社区获得性发热性疾病病因的系统评价和荟萃分析：血样TaqMan微阵列卡定量聚合酶链反应识别结果
Carl Boodman,Nitin Gupta,Cansu Cimen et al.
Carl Boodman et al.
Community-acquired febrile illness presents a significant diagnostic challenge. The TaqMan Array Card (TAC) enables simultaneous detection of many bacterial, viral, parasitic, and fungal pathogens. This systematic review aimed to characteri...
resaCPE: a rapid, low-cost colorimetric assay for the detection of carbapenemase-producing Enterobacterales [0.03%]
快速且低成本的碳青霉烯耐药肠杆菌科检测方法(RESA-CPE)
Mitchell A Jeffs,Gabhan Chalmers,Henry Wong et al.
Mitchell A Jeffs et al.
The use of carbapenem antibiotics is threatened by the global spread of carbapenemase-producing Enterobacterales (CPE), bacterial pathogens which hydrolyze these last-resort antimicrobials. Rapid detection of CPE is vital to ensure timely a...
Serology as an early diagnostic tool in pediatric patients with Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome: a post hoc analysis of a phase 2 clinical trial [0.03%]
抗志贺毒素的大肠杆菌相关溶血性尿毒综合征患儿中的血清学诊断前兆：一项II期临床试验的事后分析
Stella M Landivar,Luciano J Melli,Mariana Pichel et al.
Stella M Landivar et al.
The specific anti-O polysaccharide antibody response in Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) patients and its relevance for early diagnosis have not been previously studied in detail. In thi...
Comparison of culture and culture-free methods for comprehensive identification of mycobacteria: a single-center prospective study [0.03%]
比较培养和无菌方法全面鉴定结核分枝杆菌的差异性：一项单中心前瞻性研究
Kazuki Hashimoto,Kiyoharu Fukushima,Yuki Matsumoto et al.
Kazuki Hashimoto et al.
The genus Mycobacterium, including Mycobacterium tuberculosis and over 200 nontuberculous mycobacteria (NTM), shows wide variability in clinical outcomes and drug susceptibility. Although culture-based identification remains the gold standa...
Identification of Aspergillus at section and species levels by artificial intelligence-based microscopic morphology image recognition [0.03%]
基于人工智能的微观形态图像识别技术在曲霉属菌种鉴定中的应用研究
Meng Tan,Zhe Guo,Yanyi Wang et al.
Meng Tan et al.
Rapid and accurate identification of Aspergillus species in clinical microbiology laboratories is crucial for aspergillosis diagnosis and antifungal therapy. However, traditional methods still face challenges in distinguishing phylogenetica...
Rapid and reliable diagnosis of mucormycosis using colorimetric loop-mediated isothermal amplification [0.03%]
基于等温扩增的莫拉菌属感染床旁检测技术研发及应用研究快速且可靠地使用颜色放大循环链式反应鉴别黏菌病
Yiyou Gu,Belal A Ibrahim,Teclegiorgis Gebremariam et al.
Yiyou Gu et al.
Current diagnostic approaches for mucormycosis are often limited by low sensitivity and prolonged turnaround times, which result in delayed treatment and poor clinical outcomes. We developed a novel diagnostic method utilizing a colorimetri...
Optimizing Shigella isolation: a multi-site evaluation of laboratory culture methods for Shigella detection, speciation, and serotyping with different transport media and sample types in the Enterics for Global Health study [0.03%]
优化志贺氏菌分离：一项关于实验室培养方法的多点评估，用于在“肠道健康全球研究”中检测、分类和血清型鉴定志贺氏菌的不同运送介质和样本类型的研究
Md Taufiqur Rahman Bhuiyan,Jie Liu,Jane Juma et al.
Md Taufiqur Rahman Bhuiyan et al.
Shigella is a leading cause of diarrhea and dysentery in children younger than 5 years of age in low-resource settings, and several vaccines are in development. Due to its fastidious nature, Shigella can be difficult to culture, and eventua...
Inference of ceftobiprole susceptibility through surrogate testing of ceftaroline [0.03%]
通过替代检测头孢他啶唑喃推断头孢吡普的敏感性
Helio S Sader,Rodrigo E Mendes,David P Nicolau et al.
Helio S Sader et al.
Ceftobiprole is an advanced-generation cephalosporin active against methicillin-resistant Staphylococcus aureus and other clinically relevant bacteria. Ceftobiprole was recently (April 2024) approved for clinical use in the United States, b...
Accuracy of nanopore-based targeted next-generation sequencing assay for detection of Mycobacterium tuberculosis and drug resistance from non-sputum specimens: a multicenter prospective study in China [0.03%]
基于纳米孔的靶向下一代测序法在中国非痰标本中检测结核分枝杆菌及耐药性的多中心前瞻性研究准确性分析
Zeliang Yang,Zichun Ma,Zubi Liu et al.
Zeliang Yang et al.
Tuberculosis (TB) remains the leading cause of mortality caused by a single infectious agent. Targeted next-generation sequencing (tNGS) has become a promising molecular method for TB diagnosis, but its accuracy and application for non-sput...