Molecular mechanisms of SARS-CoV-2 entry: implications for biomedical strategies [0.03%]
SARS-CoV-2进入宿主细胞的分子机制及其对生物医学策略的影响
Irene Santamaria-Castro,Rocio Leiva-Rebollo,Sonia Marín-Wong et al.
Irene Santamaria-Castro et al.
SUMMARYThe mechanisms by which viruses enter host cells are crucial for their ability to infect and cause disease, serving as major targets for both host immune responses and therapeutic strategies. The severe acute respiratory syndrome cor...
Fatty acid synthesis and utilization in gram-positive bacteria: insights from Bacillus subtilis [0.03%]
芽孢杆菌中脂肪酸的合成和利用：来自枯草芽孢杆菌的见解
María Cecilia Mansilla,Diego de Mendoza
María Cecilia Mansilla
SUMMARYThe bacterial cytoplasmic membrane, consisting of roughly equal proportions of proteins and lipids, plays a crucial role in cellular growth, metabolism, and maintaining the cytoplasmic boundary. It is a dynamic, fluid matrix that sep...
Gabriele Neumann,Amie J Eisfeld,Yoshihiro Kawaoka
Gabriele Neumann
SUMMARYOver the past 25 years, there has been an increasing number of mammalian (including human) infections caused by avian influenza A viruses that resulted in mild to severe illnesses. These viruses typically did not spread between mamma...
A roadmap to understanding and anticipating microbial gene transfer in soil communities [0.03%]
土壤微生物基因转移的研究现状与未来展望
David L Gillett,Malyn Selinidis,Travis Seamons et al.
David L Gillett et al.
SUMMARYEngineered microbes are being programmed using synthetic DNA for applications in soil to overcome global challenges related to climate change, energy, food security, and pollution. However, we cannot yet predict gene transfer process...
Vitamin biosynthesis in the gut: interplay between mammalian host and its resident microbiota [0.03%]
肠道中的维生素生物合成：哺乳动物宿主及其常驻菌群之间的相互作用
Chiara Tarracchini,Cathy Lordan,Christian Milani et al.
Chiara Tarracchini et al.
SUMMARYIn recent years, exhaustive efforts have been made to dissect the composition of gut-associated microbial communities and associated interactions with their human host, which are thought to play a crucial role in host development, ph...
O-antigen polysaccharides in Klebsiella pneumoniae: structures and molecular basis for antigenic diversity [0.03%]
肺炎克雷伯氏菌中的O-抗原多糖：结构及其抗原多样性分子基础
Chris Whitfield,Steven D Kelly,Tom D Stanton et al.
Chris Whitfield et al.
SUMMARYKlebsiella pneumoniae is a gram-negative species, whose isolates are found in the environment and as commensals in the human gastrointestinal tract. This bacterium is among the leading causes of a range of nosocomial and community-ac...
Coinfection by multiple Trypanosoma cruzi clones: a new perspective on host-parasite relationship with consequences for pathogenesis and management of Chagas disease [0.03%]
多个克鲁兹锥虫株的共感染：宿主与寄生虫关系的新视角及其对查加斯病发病机制和管理的影响
Yves Carlier,Eric Dumonteil,Claudia Herrera et al.
Yves Carlier et al.
SUMMARYChagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi (Tc), infecting 6-7 million people. It is transmitted by insect vectors, orally, through infected tissues, or congenitally. Tc infection can progress toward ch...
Host specificity of gut microbiota associated with social bees: patterns and processes [0.03%]
与社会蜜蜂相关的肠道微生物群的宿主特异性：模式和过程
Florent Mazel,Aiswarya Prasad,Philipp Engel
Florent Mazel
SUMMARYGut microbes provide benefits to some animals, but their distribution and effects across diverse hosts are still poorly described. There is accumulating evidence for host specificity (i.e., a pattern where different microbes tend to ...
Yan-Yan Sun,Ning-Ning Liu
Yan-Yan Sun
SUMMARYThe human microbiome, including bacteria, fungi, archaea, and viruses, is intimately linked to both health and disease. The relationship between bacteria and disease has received much attention and intensive investigation, while that...
Ira Blader,Felicia Goodrum,Michael J Imperiale et al.
Ira Blader et al.