LPS in gram-negative bacterial growth and physiology: outside but fully integrated [0.03%]
革兰氏阴性菌生长和生理中的LPS：在外但完全整合在里面
Ryan A Valdez,Petra Anne Levin
Ryan A Valdez
SUMMARYFor single-celled organisms, the cell envelope is the thin barrier between life and death, responding dynamically to both the ever-expanding self and the ever-changing environment. Failure to balance these responses can lead to disas...
LPS in gram-negative bacterial growth and physiology: outside but fully integrated [0.03%]
革兰氏阴性菌生长和生理中的LPS：外部但完全整合
Ryan A Valdez,Petra Anne Levin
Ryan A Valdez
SUMMARYFor single-celled organisms, the cell envelope is the thin barrier between life and death, responding dynamically to both the ever-expanding self and the ever-changing environment. Failure to balance these responses can lead to disas...
Heather A Feaga
Heather A Feaga
SUMMARYRibosomes produce the staggering array of proteins that perform the structural and enzymatic feats of the cell. Therefore, most of the cell's energy goes toward producing ribosomes and the work performed by them. The work of the ribo...
Emma E Blackburn,Xiaorong Lin
Emma E Blackburn
SUMMARYLiquid-liquid phase separation (LLPS) drives the formation of biomolecular condensates, a conserved phenomenon across eukaryotes. This process governs diverse cellular programs, from stress response and morphogenesis to disease patho...
Rabia Fatima,Gayatri Nair,Amany Al-Anany et al.
Rabia Fatima et al.
SUMMARYHow temperate bacteriophages choose between lysis and lysogeny (dormancy) was one of the very first-and remains among the best studied-models of gene regulation. As over 75% of bacteria have a dormant phage within their genomes, the ...
Robert Karari Njenga,Hans-Georg Koch
Robert Karari Njenga
SUMMARYThe biogenesis of ribosomes and protein synthesis are among the most energy-consuming processes in living cells and therefore rate-limiting for growth, making them key targets for controlling the growth of competitors, predators, and...
Siobhan A Cusack,Sebastián Riquelme-Barrios,Luis Rivera-Montero et al.
Siobhan A Cusack et al.
SUMMARYRNA modifications in the tRNA, rRNA, and mRNA constitute a widespread layer of post-transcriptional gene regulation, commonly known as the epitranscriptome. In bacteria, tRNA and rRNA modifications are well documented and play essent...
Helicobacter pylori geographic variation: a window into global differences in gastric cancer incidence [0.03%]
幽门螺杆菌的地域差异：一扇展示胃癌发病率全球差异的窗口
Chiamaka D Okoye,Georgia C Caso,Timothy L Cover
Chiamaka D Okoye
SUMMARYHelicobacter pylori infection is the strongest known risk factor for gastric cancer, a leading cause of cancer-related deaths worldwide. There is marked global geographic variation in both the incidence of gastric cancer and genetic ...
Lifestyle plasticity and the shared hypocrealean toolkit across Fusarium, Metarhizium, and Trichoderma [0.03%]
裂褶菌、绿僵菌和青霉菌共用的钩丝核盘菌工具箱及其生活方式的可塑性
Raymond J St Leger,Huiyu Sheng,Alexander X Hafer
Raymond J St Leger
SUMMARYFungi in the genera Fusarium, Metarhizium, and Trichoderma (FMT) are traditionally defined by their roles as plant pathogens, insect pathogens, and mycoparasites, respectively. However, these classifications obscure both their shared...
LD-transpeptidation in bacterial cell walls: biochemical principles and functional diversity [0.03%]
细菌细胞壁中的LD-转肽作用：生化原理与功能多样性
Barbara Walenkiewicz,Laura Alvarez,Felipe Cava
Barbara Walenkiewicz
SUMMARYPeptidoglycan (PG) is a dynamic, load-bearing polymer whose crosslinking chemistry governs envelope mechanics, growth modes, and stress tolerance. For decades, PG crosslinking was viewed primarily through the lens of penicillin-bindi...