Pseudomonas aeruginosa biofilm-deficient mutants undergo parallel evolution during chronic infection [0.03%]
绿脓杆菌在慢性感染中无生物膜突变体的平行进化现象
Erin S Gloag,Christopher W Marshall,Nanami Kubota et al.
Erin S Gloag et al.
Pseudomonas aeruginosa readily adapts to infection by acquiring stable and heritable mutations. Previously, we discovered that the first adaptations in a porcine wound model were rugose small-colony variants (RSCVs) caused by mutations in t...
The versatility of the CHASE domain in one-component systems of c-di-GMP signal transduction from P. aeruginosa [0.03%]
铜绿假单胞菌c-di-GMP信号转导系统中CHASE结构域的多样性及多功能性
Simone Angeli,Chiara Scribani-Rossi,Giulio Colasanto et al.
Simone Angeli et al.
Cyclic di-GMP (c-di-GMP) is a key bacterial second messenger that regulates a wide range of cellular processes, including biofilm formation and virulence. Multi-domain one-component systems regulate c-di-GMP synthesis and turnover in respon...
Addison Frese,Zhi Zhao,Junjie Zhang et al.
Addison Frese et al.
Antimicrobial resistance is a growing global health crisis, with ESKAPE pathogens, such as Acinetobacter species, contributing significantly to hospital-acquired infections. These bacteria employ various virulence factors, including extrace...
Biological and clinical significance of iron in Pseudomonas aeruginosa biofilms [0.03%]
铁离子在铜绿假单胞菌生物被膜中的生物学和临床意义
Jacob M Weiner,Rhishita Chourashi,Khady O Ouattara et al.
Jacob M Weiner et al.
Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium that causes diverse opportunistic infections in vulnerable populations. P. aeruginosa is innately resistant to many therapeutic agents, and biofilm-mediated infections demonstra...
TsrA modulates type III secretion system 2 expression as a co-regulator of H-NS in Vibrio parahaemolyticus [0.03%]
铜绿假单胞菌H-NS调节蛋白的条件依赖性抑制作用及其对毒力基因表达的影响
Tan Paramita Wibowo Sutanto,Andre Pratama,Eiji Ishii et al.
Tan Paramita Wibowo Sutanto et al.
Vibrio parahaemolyticus, a gram-negative marine bacterium, is a major cause of seafood-borne gastroenteritis worldwide. This pathogen relies on type III secretion system 2 (T3SS2), which is encoded on a pathogenicity island, for its enterop...
Formate hydrogenlyase is essential for pH homeostasis, maintenance of ATP levels, and CO2 provision in stationary-phase Escherichia coli [0.03%]
甲酸氢化酶对大肠杆菌静息期pH平衡、ATP水平维持以及CO2供应是必需的
Christopher Erdmann,Liana Vanyan,Karen Trchounian et al.
Christopher Erdmann et al.
Formate hydrogenlyase (FHL) enzymes are evolutionarily related to mitochondrial complex I. Formate-inducible FHL-1 of Escherichia coli catalyzes disproportionation of formic acid into H2 and CO2 during mixed-acid fermentation. In contrast t...
A sterol reductase responsible for the unusual 8(14)-unsaturation in bacterial sterol production and degradation [0.03%]
Alysha K Lee,José-Luis Giner,Paula V Welander
Alysha K Lee
Sterols are a class of lipids that play a crucial role in human health through their essential physiological roles and as a point of interaction between commensal and pathogenic bacteria. The biosynthesis and modification of these lipids is...
Adaptive evolution of electron transfer pathways in Thermoanaerobacterium saccharolyticum [0.03%]
热厌氧菌糖发酵株电子转移途径的适应进化研究
João H T M Fabri,Shu Huang,T Emme Burgin et al.
João H T M Fabri et al.
Thermoanaerobacterium saccharolyticum is an anaerobic, thermophilic bacterium that has been proposed for use in consolidated bioprocessing in coculture with cellulolytic bacteria such as Clostridium thermocellum for ethanol production. Alth...
Adaptive evolution resulted in three subtypes of the Riemerella anatipestifer crpR1 gene [0.03%]
适应性进化导致了里氏杆菌安德森亚种crpR1基因的三种亚型
Jialing Wang,Xiaoli Du,Hui Yin et al.
Jialing Wang et al.
The global transcription regulator CRP protein controls diverse cellular processes in many bacteria. Our group previously reported that Tn4531 insertion in FIP52_09345 (designated as crpR1), which encodes a special CRP protein without the H...
Mfd interacts with RNA polymerase to modulate flagellum-dependent motility, chemotaxis, and population heterogeneity in the stationary phase of Bacillus subtilis [0.03%]
Mfd通过与RNA聚合酶相互作用调节枯草芽孢杆菌停滞期鞭毛依赖性运动、趋化性和群体异质性
Jessica Grifaldo,Hilda Leyva-Sanchez,Khristian Rosales et al.
Jessica Grifaldo et al.
Bacillus subtilis is a model for cell differentiation, capable of transitioning between distinct states: a sessile, chained state (often associated with biofilm formation), and a motile, planktonic state. This transition is governed by a co...