mcr-1 Gene Expression Modulates the Inflammatory Response of Human Macrophages to Escherichia coli [0.03%]
mcr-1基因的表达调节人体巨噬细胞对大肠杆菌的炎症反应
Giorgio Mattiuz,Sabrina Nicolò,Alberto Antonelli et al.
Giorgio Mattiuz et al.
MCR-1 is a plasmid-encoded phosphoethanolamine transferase able to modify the lipid A structure. It confers resistance to colistin and was isolated from human, animal, and environmental strains of Enterobacteriaceae, raising serious global ...
A 20-Mer Peptide Derived from the Lectin Domain of SP-A2 Decreases Tumor Necrosis Factor Alpha Production during Mycoplasma pneumoniae Infection [0.03%]
一种由SP-A2凝集素结构域衍生的20肽在肺炎支原体感染过程中减少肿瘤坏死因子α生成
Usir S Younis,Hong Wei Chu,Monica Kraft et al.
Usir S Younis et al.
Human surfactant protein-A2 (hSP-A2) is a component of pulmonary surfactant that plays an important role in the lung's immune system by interacting with viruses, bacteria, and fungi to facilitate pathogen clearance and by downregulating inf...
NHR-49 Transcription Factor Regulates Immunometabolic Response and Survival of Caenorhabditis elegans during Enterococcus faecalis Infection [0.03%]
肠杆菌感染期间NHR-49转录因子调节钙黏菌免疫代谢反应和存活状况
Madhumanti Dasgupta,Meghana Shashikanth,Anjali Gupta et al.
Madhumanti Dasgupta et al.
Immune response to pathogens is energetically expensive to the host; however, the cellular source of energy to fuel immune response remains unknown. In this study, we show that Caenorhabditis elegans exposed to pathogenic Gram-positive and ...
Legionella pneumophila Excludes Autophagy Adaptors from the Ubiquitin-Labeled Vacuole in Which It Resides [0.03%]
Legionella pneumophila阻止泛素标记的小体向自噬适配子转移
Titilayo O Omotade,Craig R Roy
Titilayo O Omotade
Xenophagy targets intracellular pathogens for destruction by the host autophagy pathway. Ubiquitin chains are conjugated to xenophagic targets and recruit multiple autophagy adaptors. The intracellular pathogen Legionella pneumophila reside...
The uroS and yifB Genes Conserved among Tetrapyrrole Synthesizing-Deficient Bacteroidales Are Involved in Bacteroides fragilis Heme Assimilation and Survival in Experimental Intra-abdominal Infection and Intestinal Colonization [0.03%]
四吡咯合成缺陷菌阴沟杆菌科中保守的uroS和yifB基因参与脆弱拟杆菌血红素同化及实验性腹内感染和肠定植中的存活
Anita C Parker,Hector A Bergonia,Nathaniel L Seals et al.
Anita C Parker et al.
The human intestinal anaerobic commensal and opportunistic pathogen Bacteroides fragilis does not synthesize the tetrapyrrole protoporphyrin IX in order to form heme that is required for growth stimulation and survival in vivo Consequently,...
Mycobacterium abscessus Clearance by Neutrophils Is Independent of Autophagy [0.03%]
鸟分枝杆菌脓肿亚种清除不受自噬影响
Kerstin Pohl,Xue A Grimm,Silvia M Caceres et al.
Kerstin Pohl et al.
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, is increasingly prevalent in chronic lung disease, including cystic fibrosis, and infections are characterized by neutrophil-dominated environments. However, mechanism...
Cryptococcus neoformans Evades Pulmonary Immunity by Modulating Xylose Precursor Transport [0.03%]
新生隐球菌通过调节木糖前体转运来逃避肺部免疫反应
Lucy X Li,Camaron R Hole,Javier Rangel-Moreno et al.
Lucy X Li et al.
Cryptococcus neoformans is a fungal pathogen that kills almost 200,000 people each year and is distinguished by abundant and unique surface glycan structures that are rich in xylose. A mutant strain of C. neoformans that cannot transport xy...
Chlamydia Lipooligosaccharide Has Varied Direct and Indirect Roles in Evading both Innate and Adaptive Host Immune Responses [0.03%]
沙眼衣原体脂寡糖通过直接和间接的多种方式躲避宿主先天性和适应性免疫应答
Xisheng Wang,Daniel D Rockey,Brian P Dolan
Xisheng Wang
Chlamydia bacteria are obligate intracellular pathogens which can cause a variety of disease in humans and other vertebrate animals. To successfully complete its life cycle, Chlamydia must evade both intracellular innate immune responses an...
Morphological and Motility Features of the Stable Bleb-Driven Monopodial Form of Entamoeba and Its Importance in Encystation [0.03%]
稳定的伪足驱动单极形式的溶组织内阿米巴的形态和运动特征及其在囊化过程中的重要意义
Deepak Krishnan,Sudip Kumar Ghosh
Deepak Krishnan
Entamoeba histolytica and its reptilian counterpart and encystation model Entamoeba invadens formed a polarized monopodial morphology when treated with pentoxifylline. This morphology was propelled by retrograde flow of the cell surface res...
Group A Streptococcus AdcR Regulon Participates in Bacterial Defense against Host-Mediated Zinc Sequestration and Contributes to Virulence [0.03%]
链球菌属GAS的AdcR调节子参与了对宿主介导的锌隔离作用的抵抗并有助于毒力
Nishanth Makthal,Hackwon Do,Brian M Wendel et al.
Nishanth Makthal et al.
Colonization by pathogenic bacteria depends on their ability to overcome host nutritional defenses and acquire nutrients. The human pathogen group A streptococcus (GAS) encounters the host defense factor calprotectin (CP) during infection. ...