Bronchial Epithelial Tet2 Maintains Epithelial Integrity during Acute Pseudomonas aeruginosa Pneumonia [0.03%]
急性铜绿假单胞菌肺炎期间气道上皮Tet2维持上皮完整性
Wanhai Qin,Xanthe Brands,Cornelis Van&#x;t Veer et al.
Wanhai Qin et al.
Respiratory epithelial cells are important for pulmonary innate immune responses during Pseudomonas aeruginosa infection. Tet methylcytosine dioxygenase 2 (Tet2) has been implicated in the regulation of host defense by myeloid and lymphoid ...
Role of metAB in Methionine Metabolism and Optimal Chicken Colonization in Campylobacter jejuni [0.03%]
AB代谢物在甲硫氨酸代谢和空肠弯曲菌鸡优化定植中的作用
Brandon Ruddell,Alan Hassall,Orhan Sahin et al.
Brandon Ruddell et al.
Campylobacter jejuni is a zoonotic pathogen and is one of the leading causes of human gastroenteritis worldwide. C. jejuni IA3902 (representative of the sheep abortion clone) is genetically similar to C. jejuni W7 (representative of strain ...
Effect of CARD9 Deficiency on Neutrophil-Mediated Host Defense against Pulmonary Infection with Streptococcus pneumoniae [0.03%]
CARD9缺乏对肺炎链球菌所致肺部感染的中性粒细胞介导的宿主防御的影响
Shigenari Ishizuka,Rin Yokoyama,Ko Sato et al.
Shigenari Ishizuka et al.
Streptococcus pneumoniae is a major causative bacterium of community-acquired pneumonia. Dendritic cell-associated C-type lectin-2 (dectin-2), one of the C-type lectin receptors (CLRs), was previously reported to play a pivotal role in host...
Akkermansia muciniphila and Its Pili-Like Protein Amuc_1100 Modulate Macrophage Polarization in Experimental Periodontitis [0.03%]
Akkermansia muciniphila及其类似蛋白Amuc_1100在实验性牙周炎中调节巨噬细胞的极化
Hannah Mulhall,Jeanne M DiChiara,Matthew Deragon et al.
Hannah Mulhall et al.
Periodontitis is a chronic inflammatory disease triggered by dysbiosis of the oral microbiome. Porphyromonas gingivalis is strongly implicated in periodontal inflammation, gingival tissue destruction, and alveolar bone loss through sustaine...
Secretion of c-di-AMP by Listeria monocytogenes Leads to a STING-Dependent Antibacterial Response during Enterocolitis [0.03%]
单核细胞李斯特菌通过分泌c-di-AMP引发肠炎期间STING依赖的抗菌反应
Alexander Louie,Varaang Bhandula,Daniel A Portnoy
Alexander Louie
Stimulator of interferon genes (STING) acts as a cytoplasmic signaling hub of innate immunity that is activated by host-derived or bacterially derived cyclic dinucleotides. Listeria monocytogenes is a foodborne, facultative intracellular pa...
Call for Original Research Papers for a Special Collection in Infection and Immunity: the Microbiome and Infection [0.03%]
《感染与免疫》特刊征稿：微生物群与感染原创性研究论文
Manuela Raffatellu,Andreas J Bäumler
Manuela Raffatellu
Identification of Autophagy-Inhibiting Factors of Mycobacterium tuberculosis by High-Throughput Loss-of-Function Screening [0.03%]
通过高通量功能缺失筛选鉴定结核分枝杆菌自噬抑制因子
Emily J Strong,Kristen L Jurcic Smith,Neeraj K Saini et al.
Emily J Strong et al.
The interaction of host cells with mycobacteria is complex and can lead to multiple outcomes ranging from bacterial clearance to progressive or latent infection. Autophagy is recognized as one component of host cell responses that has an es...
Success of Escherichia coli O25b:H4 Sequence Type 131 Clade C Associated with a Decrease in Virulence [0.03%]
与毒力降低相关的埃希氏大肠杆菌O25b:H4序列类型131分支C的成功演变
Marion Duprilot,Alexandra Baron,François Blanquart et al.
Marion Duprilot et al.
Escherichia coli O25b:H4 sequence type 131 (ST131), which is resistant to fluoroquinolones and which is a producer of CTX-M-15, is globally one of the major extraintestinal pathogenic E. coli (ExPEC) lineages. Phylogenetic analyses showed t...
Paul Briaud,Ronan K Carroll
Paul Briaud
Extracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells. Bacterial membrane vesicles were discovered over 60 years ago and have been extensively studied in Gram-negative bacteria. During th...
CsrA Supports both Environmental Persistence and Host-Associated Growth of Acinetobacter baumannii [0.03%]
CsrA 支持鲍曼不动杆菌的环境持久性和宿主相关生长
John M Farrow rd,Greg Wells,Samantha Palethorpe et al.
John M Farrow rd et al.
Acinetobacter baumannii is an opportunistic and frequently multidrug-resistant Gram-negative bacterial pathogen that primarily infects critically ill individuals. Indirect transmission from patient to patient in hospitals can drive infectio...