Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses [0.03%]
人诺如病毒广谱治疗性抗体Fc-纳米体的开发
Grant S Hansman,Gargi Kher,Anna D Svirina et al.
Grant S Hansman et al.
Human norovirus was discovered more than five decades ago and is a widespread cause of outbreaks of acute gastroenteritis. There are no approved vaccines or antivirals currently available. However, norovirus inhibitors, including capsid-spe...
Correction for Huang et al., "p17-Modulated Hsp90/Cdc37 Complex Governs Oncolytic Avian Reovirus Replication by Chaperoning p17, Which Promotes Viral Protein Synthesis and Accumulation of Viral Proteins σC and σA in Viral Factories" [0.03%]
黄等人文章的勘误：“p17-调节Hsp90/Cdc37复合体通过促进病毒蛋白合成及σC和σA蛋白在病毒工厂中积累来调控溶瘤禽类呼肠孤病毒复制”中的更正
Wei-Ru Huang,Jyun-Yi Li,Yi-Ying Wu et al.
Wei-Ru Huang et al.
Published Erratum
Journal of virology. 2024 Jul 23;98(7):e0092024. DOI:10.1128/jvi.00920-24 2024
Yannick Munyeku-Bazitama,Takeshi Saito,Takanari Hattori et al.
Yannick Munyeku-Bazitama et al.
Tibroviruses are novel rhabdoviruses detected in humans, cattle, and arthropods. Four tibroviruses are known to infect humans: Bas-Congo virus (BASV), Ekpoma virus 1 (EKV-1), Ekpoma virus 2, and Mundri virus. However, since none of them has...
SARS-CoV-2 BA.4/5 infection triggers more cross-reactive FcγRIIIa signaling and neutralization than BA.1, in the context of hybrid immunity [0.03%]
与BA.1相比，BA.4/5感染在杂交免疫背景下触发更多的交叉反应性FcγRIIIa信号传导和中和作用
Simone I Richardson,Nonkululeko Mzindle,Thopisang Motlou et al.
Simone I Richardson et al.
SARS-CoV-2 variants of concern (VOCs) differentially trigger neutralizing and antibody-dependent cellular cytotoxic (ADCC) antibodies with variable cross-reactivity. Omicron BA.4/5 was approved for inclusion in bivalent vaccination boosters...
Simultaneous quantitation of neutralizing antibodies against all four dengue virus serotypes using optimized reporter virus particles [0.03%]
优化报告病毒颗粒同时定量四种登革病毒血清型中和抗体的方法
Matthias Lingemann,Emérito Amaro-Carambot,Elaine W Lamirande et al.
Matthias Lingemann et al.
Serum-neutralizing antibody titers are a critical measure of vaccine immunogenicity and are used to determine flavivirus seroprevalence in study populations. An effective dengue virus (DENV) vaccine must confer simultaneous protection again...
Comprehensive proteomic analysis of HCoV-OC43 virions and virus-modulated extracellular vesicles [0.03%]
HCoV-OC43病毒体和病毒调节的细胞外囊泡的全面蛋白质组分析
Negar Joharinia,Éric Bonneil,Nathalie Grandvaux et al.
Negar Joharinia et al.
Viruses are obligate parasites that depend on the cellular machinery for their propagation. Several viruses also incorporate cellular proteins that facilitate viral spread. Defining these cellular proteins is critical to decipher viral life...
Six adenoviral vectored African swine fever virus genes protect against fatal disease caused by genotype I challenge [0.03%]
六种腺病毒载体的非洲猪瘟病毒基因保护免受1型基因挑战引起的致命疾病侵害
Raquel Portugal,Hannah Goldswain,Rebecca Moore et al.
Raquel Portugal et al.
African swine fever virus causes a lethal hemorrhagic disease in domestic swine and wild boar for which currently licensed commercial vaccines are only available in Vietnam. Development of subunit vaccines is complicated by the lack of info...
Justine Girard,Olivier Le Bihan,Joséphine Lai-Kee-Him et al.
Justine Girard et al.
Chikungunya virus (CHIKV) is a mosquito-borne pathogen responsible for an acute musculoskeletal disease in humans. Replication of the viral RNA genome occurs in specialized membranous replication organelles (ROs) or spherules, which contain...
The pseudogene GBP1P1 suppresses influenza A virus replication by acting as a protein decoy for DHX9 [0.03%]
假基因GBP1P1通过作为DHX9的蛋白质陷阱来抑制A型流感病毒的复制
Xiaohang Yu,Jiaxin Tian,Yihe Wang et al.
Xiaohang Yu et al.
Recently, substantial evidence has demonstrated that pseudogene-derived long noncoding RNAs (lncRNAs) as regulatory RNAs have been implicated in basic physiological processes and disease development through multiple modes of functional inte...
Recognition of HIV-1-infected fibrocytes lacking Nef-mediated HLA-B downregulation by HIV-1-specific T cells [0.03%]
HIV-1特异性T细胞识别缺乏Nef介导的HLA-B下调的HIV-1感染成纤维细胞
Nozomi Kuse,Osamu Noyori,Naofumi Takahashi et al.
Nozomi Kuse et al.
Fibrocytes were reported to be host cells for HIV-1, but the immunological recognition of HIV-1-infected fibrocytes has not been studied. Here, we investigated the recognition of HIV-1-infected fibrocytes by HIV-1-specific CD8+ T cells. CD8...