Breadth and polyfunctionality of T cell responses to human cytomegalovirus in men who have sex with men: relationship with HIV infection and frailty [0.03%]
人类免疫缺陷病毒感染和衰老对男性艾滋病病毒感染者细胞免疫反应的广度和多样性的影响研究：巨细胞病毒的交叉反应作用
Weiying Zhang,Tricia L Nilles,Jay H Bream et al.
Weiying Zhang et al.
Cytomegalovirus (CMV)-seropositive adults have large T cell responses to a wide range of CMV proteins; these responses have been associated with chronic inflammation and frailty in people with or without HIV infection. We analyzed the relat...
Giant viruses inhibit superinfection by downregulating phagocytosis in Acanthamoeba [0.03%]
巨病毒通过下调芽囊原虫的吞噬作用来抑制重复感染
Isabella L M Aquino,Erik Sousa Reis,Rafaella Oliveira Almeida Mattos Moreira et al.
Isabella L M Aquino et al.
In the context of the virosphere, viral particles can compete for host cells. In this scenario, some viruses block the entry of exogenous virions upon infecting a cell, a phenomenon known as superinfection inhibition. The molecular mechanis...
Neu5Gc binding loss of subtype H7 influenza A virus facilitates adaptation to gallinaceous poultry following transmission from waterbirds [0.03%]
N-乙酰五氢神经节苷脂结合能力的丧失促进H7亚型甲型流感病毒从水鸟传播到家禽后的适应性进化
Minhui Guan,Thomas J DeLiberto,Aijing Feng et al.
Minhui Guan et al.
Between 2013 and 2018, the novel A/Anhui/1/2013 (AH/13)-lineage H7N9 virus caused at least five waves of outbreaks in humans, totaling 1,567 confirmed human cases in China. Surveillance data indicated a disproportionate distribution of poul...
Variable fitness effects of bacteriophage resistance mutations in Escherichia coli: implications for phage therapy [0.03%]
耐噬菌体突变在大肠杆菌中的可变适应度效应及其对噬菌体疗法的影响
Baptiste Gaborieau,Raphaëlle Delattre,Sandrine Adiba et al.
Baptiste Gaborieau et al.
Bacteria exposed to bactericidal treatment, such as antibiotics or bacteriophages (phages), often develop resistance. While phage therapy is proposed as a solution to the antibiotic resistance crisis, the bacterial resistance emerging durin...
Endogenous nege-like viral elements in arthropod genomes reveal virus-host coevolution and ancient history of two plant virus families [0.03%]
节肢动物基因组中的内源性病毒样元件揭示了植物病毒的共进化及其起源历史
Gang Lu,Zhuang-Xin Ye,Yu-Hua Qi et al.
Gang Lu et al.
Negevirus is a recently proposed taxon of arthropod-infecting virus, which is associated with plant viruses of two families (Virgaviridae and Kitaviridae). Nevertheless, the evolutionary history of negevirus-host and its relationship with p...
Correction for Lee et al., "Cholesterol Effectively Blocks Entry of Flavivirus" [0.03%]
纠正李等人的论文“胆固醇有效阻止黄病毒的进入”中的错误
Chyan-Jang Lee,Hui-Ru Lin,Ching-Len Liao et al.
Chyan-Jang Lee et al.
Published Erratum
Journal of virology. 2024 Oct 22;98(10):e0113124. DOI:10.1128/jvi.01131-24 2024
Correction for Welsh et al., "Sequence polymorphisms in the reovirus σ1 attachment protein modulate encapsidation efficiency and replication in mice" [0.03%]
威尔士等，《重组病毒σ1蛋白的序列多态性可调节小鼠体内的包装效率和复制》的更正
Olivia L Welsh,Alexa N Roth,Danica M Sutherland et al.
Olivia L Welsh et al.
Published Erratum
Journal of virology. 2024 Oct 22;98(10):e0131424. DOI:10.1128/jvi.01314-24 2024
The multifaceted roles of selective autophagy receptors in viral infections [0.03%]
选择性自噬受体在病毒感染中的多种作用
Rui Luo,Tao Wang,Jing Lan et al.
Rui Luo et al.
Selective autophagy is a protein clearance mechanism mediated by evolutionarily conserved selective autophagy receptors (SARs), which specifically degrades misfolded, misassembled, or metabolically regulated proteins. SARs help the host to ...
DDX RNA helicases: key players in cellular homeostasis and innate antiviral immunity [0.03%]
DDX解旋酶：细胞稳态和天然抗病毒免疫的关键因子
Iulia Tapescu,Sara Cherry
Iulia Tapescu
RNA helicases are integral in RNA metabolism, performing important roles in cellular homeostasis and stress responses. In particular, the DExD/H-box (DDX) helicase family possesses a conserved catalytic core that binds structural features r...
Development of an intestinal mucosa ex vivo co-culture model to study viral infections [0.03%]
体外肠道黏膜共培养模型的开发以研究病毒感染
Emilia Barreto-Duran,Aleksandra Synowiec,Artur Szczepański et al.
Emilia Barreto-Duran et al.
Studying viral infections necessitates well-designed cell culture models to deepen our understanding of diseases and develop effective treatments. In this study, we present a readily available ex vivo 3D co-culture model replicating the hum...