Comparison of the biological properties of bat-derived filovirus envelope glycoproteins [0.03%]
来自蝙蝠的丝状病毒包膜糖蛋白生物学性质的比较研究
Francois Edidi-Atani,Yannick Munyeku Bazitama,Hiroko Miyamoto et al.
Francois Edidi-Atani et al.
Although some filoviruses, such as Ebola virus (EBOV) and Marburg virus (MARV), are highly pathogenic in humans, novel filoviruses, including Lloviu virus (LLOV), Bombali virus (BOMV), Mengla virus (MLAV), and Dehong virus (DEHV), whose bio...
Discontinuous template switching generates coronavirus subgenomic RNAs from the 3' viral genome end by 5' to 3' transcription [0.03%]
通过5'到3'转录从冠状病毒基因组的3'-末端生成次基因组RNA的不连续模板切换机制
Ayslan Castro Brant,Zhe Hu,Angelika Zelma Chen et al.
Ayslan Castro Brant et al.
In coronavirus (CoV)-infected cells, several structural and accessory proteins are synthesized from subgenome RNAs (sgRNA) containing a common genomic 5'-leader followed by a given open reading frame (ORF). We report that the abundance of t...
Respiratory syncytial virus phosphoprotein has NTPase and helicase-like activities [0.03%]
呼吸道合胞病毒磷酸蛋白具有NTP酶和解旋酶活性
Ting Shu,Xiaotong Wang,Yiyang Li et al.
Ting Shu et al.
Respiratory syncytial virus (RSV), a non-segmented, negative-sense RNA virus (NNSV) in the family Pneumoviridae, represents a significant global health burden causing severe lower respiratory tract infections in infants and immunocompromise...
HCC-derived SNU cell lines as model systems to study HBV life cycle [0.03%]
HBV生命活动周期研究中的肝细胞癌SNU细胞系模型的作用
Igor Zaiets,Oleksandra Chazova,Sumedha Gunewardena et al.
Igor Zaiets et al.
Human SNU cell lines, derived from hepatocellular carcinomas associated with chronic hepatitis B virus (HBV) infection, were examined. The analysis of intracellular RNA and DNA markers of HBV replication and examination of HBV RNA readss co...
A novel ZIKV-targeted scRNA-seq method for precise quantification of ZIKV RNA [0.03%]
一种新型ZIKV靶向scRNA-seq方法实现对ZIKV RNA的精准定量
Yang Zhou,Libo Liu,Wei Yang et al.
Yang Zhou et al.
Zika virus (ZIKV), transmitted by mosquitoes, poses a serious public health threat. Currently, precise quantitative diagnostic methods are lacking. Existing single-cell RNA-sequencing (scRNA-seq) techniques are challenged to detect ZIKV RNA...
Cytoplasmic translocation of tripartite motif-containing 28 is critical for PRRSV-induced autophagy through promoting Vps34-Beclin1 complex formation [0.03%]
三聚体 motifs 包含的 28 胞质转位对促进 Vps34-Beclin1 复合物形成以及嗜性诱导自噬至关重要
Meng Chen,Yuna Zhao,Hui An et al.
Meng Chen et al.
Autophagy, as a highly conserved cellular metabolic regulation mechanism, is a double-edged sword and plays multiple roles in viral infections processes. As a member of the Arteriviridae family within the order Nidovirales, the porcine repr...
Variation in virion phosphatidylserine content drives differential GAS6 binding among closely related flaviviruses [0.03%]
病毒磷脂酰丝氨酸含量的差异驱动黄病毒亚科中相关病毒结合GAS6的差别
Lizhou Zhang,Byoung-Shik Shim,Claire Kitzmiller et al.
Lizhou Zhang et al.
Many enveloped viruses engage phosphatidylserine (PS) receptors to enter cells, a phenomenon known as "apoptotic mimicry." We previously reported that Zika virus (ZIKV), but not closely related West Nile virus (WNV) or dengue virus (DENV), ...
GCN2 enhances host survival and drives eIF2α phosphorylation during mouse adenovirus type 1 infection [0.03%]
GCN2通过增强宿主存活和驱动鼠腺病毒1型感染过程中eIF2α磷酸化来抑制病毒生长
Luiza A Castro Jorge,Daniel F Edwards rd,Rosario Labastida et al.
Luiza A Castro Jorge et al.
The integrated stress response (ISR) is a cellular signaling pathway that reduces protein synthesis in the face of cellular stress, including viral infection. Two eukaryotic initiation factor 2α (eIF2α) kinases, protein kinase R (PKR) and...
Correction for Shao et al., "Polyubiquitination of APOBEC3G Is Essential for Its Degradation by HIV-1 Vif" [0.03%]
对Sha等人《APOBEC3G的多泛素化对于其由人类免疫缺陷病毒Ⅰ型Vif降解是必要的》一文的更正
Qiujia Shao,Yudi Wang,James E K Hildreth et al.
Qiujia Shao et al.
Published Erratum
Journal of virology. 2025 Sep 23:e0136825. DOI:10.1128/jvi.01368-25 2025
Evolution of BA.2.86 to JN.1 reveals that functional changes in non-structural viral proteins are required for fitness of SARS-CoV-2 [0.03%]
BA.2.86进化为JN.1表明，SARS-CoV-2的功能适应需要非结构病毒蛋白的变化
Shuhei Tsujino,Masumi Tsuda,Naganori Nao et al.
Shuhei Tsujino et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is still circulating among humans, leading to the continuous evolution. SARS-CoV-2 Omicron JN.1 evolved from a distinc...