Design, synthesis, and biological activity evaluation of BACE1 inhibitors with antioxidant activity [0.03%]
具有抗氧化活性的BACE1抑制剂的设计、合成及生物活性评价
He-Min Li,Shao-Peng Yu,Tian-Yuan Fan et al.
He-Min Li et al.
The proteolytic enzyme β-secretase (BACE1) plays a central role in the synthesis of the pathogenic β-amyloid peptides (Aβ) in Alzheimer's disease (AD), antioxidants could attenuate the AD syndrome and prevent the disease progression. In ...
Design, synthesis, and biological activity evaluation of BACE1 inhibitors with antioxidant activity [0.03%]
具有抗氧化活性的BACE1抑制剂的设计、合成及生物活性评价
He-Min Li,Shao-Peng Yu,Tian-Yuan Fan et al.
He-Min Li et al.
The proteolytic enzyme β-secretase (BACE1) plays a central role in the synthesis of the pathogenic β-amyloid peptides (Aβ) in Alzheimer's disease (AD), antioxidants could attenuate the AD syndrome and prevent the disease progression. In ...
Antiviral effects of a niobium-substituted heteropolytungstate on hepatitis B virus-transgenic mice [0.03%]
Nb取代杂多化合物的抗乙肝病毒活性研究
Qingmei Li,Hong Zhang,Yanfei Qi et al.
Qingmei Li et al.
To study the efficacy of a polyoxometalate, Cs2 K4 Na[SiW9 Nb3 O40 ]·H2 O, as an antiviral treatment in HBV transgenic mice. HBV transgenic mice were treated with Cs2 K4 Na[SiW9 Nb3 O40 ]·H2 O by intragastric administration. Adefovir and ...
Antiviral effects of a niobium-substituted heteropolytungstate on hepatitis B virus-transgenic mice [0.03%]
铌取代杂多钨酸盐抗乙肝病毒的体外实验与活体内实验研究
Qingmei Li,Hong Zhang,Yanfei Qi et al.
Qingmei Li et al.
To study the efficacy of a polyoxometalate, Cs2 K4 Na[SiW9 Nb3 O40 ]·H2 O, as an antiviral treatment in HBV transgenic mice. HBV transgenic mice were treated with Cs2 K4 Na[SiW9 Nb3 O40 ]·H2 O by intragastric administration. Adefovir and ...
Spidroin in carbopol-based gel promotes wound healing in earthworm's skin model [0.03%]
基于卡波姆凝胶的spidroin促进地龙皮肤模型伤口愈合
Noura H Abd Ellah,Fatma El-Zahraa A Abd El-Aziz,Sara A Abouelmagd et al.
Noura H Abd Ellah et al.
Spider silk's regenerative, biocompatible, and antimicrobial properties render it a promising biomaterial for wound healing promotion. Spidroin as the main protein component of spider silks was used in this study to evaluate the potential e...
Spidroin in carbopol-based gel promotes wound healing in earthworm's skin model [0.03%]
基于卡波姆凝胶的蜘蛛丝蛋白促进地表模型伤口愈合
Noura H Abd Ellah,Fatma El-Zahraa A Abd El-Aziz,Sara A Abouelmagd et al.
Noura H Abd Ellah et al.
Spider silk's regenerative, biocompatible, and antimicrobial properties render it a promising biomaterial for wound healing promotion. Spidroin as the main protein component of spider silks was used in this study to evaluate the potential e...
Mohammad S Hareedy,Esraa A Ahmed,Marwa F Ali
Mohammad S Hareedy
Montelukast (MNK) has prominent anti-inflammatory and antioxidant activities. It can protect the liver in different hepatotoxic models in animals. Simvastatin (SMV) is one of commonly used lipid lowering drugs for treatment of dyslipidemia ...
Mohammad S Hareedy,Esraa A Ahmed,Marwa F Ali
Mohammad S Hareedy
Montelukast (MNK) has prominent anti-inflammatory and antioxidant activities. It can protect the liver in different hepatotoxic models in animals. Simvastatin (SMV) is one of commonly used lipid lowering drugs for treatment of dyslipidemia ...
Modified-release oral pellets for duodenum delivery of doxycycline hyclate [0.03%]
羟氨苄多西环素改性释药口服颗粒制剂及其制法
Ying Huang,Zhengwei Huang,Mingjun Wu et al.
Ying Huang et al.
To minimize the gastric and esophageal injury effect, a system to deliver doxycycline hyclate (DOXY) to the duodenum area is needed. DOXY-containing modified-release oral pellets (DMOP) coated with hydroxypropyl methylcellulose phthalate HP...
Optimization of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives as inhibitors of monoamine oxidase [0.03%]
优化吲哚二酮和吲哚二腈衍生物作为单胺氧化酶抑制剂的研究
Zhanna V Chirkova,Mariya V Kabanova,Sergey I Filimonov et al.
Zhanna V Chirkova et al.
In recent studies, we have investigated the monoamine oxidase (MAO) inhibition properties of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives. Since numerous high potency MAO inhibitors are present among these chemic...