Malignant Peripheral Nerve Sheath Tumor (MPNST) With Smooth Muscle Differentiation of the Uterus-A Case Report With Emphasis on Diagnostic Pitfalls and Value of DNA Methylation Analysis [0.03%]
子宫平滑肌分化恶性外周神经鞘瘤(MPNST)一例并强调诊断陷阱和DNA甲基化分析的价值
Horace M H Cheung,Anthony P Y Liu,Maximus C F Yeung
Horace M H Cheung
With no more than two dozen cases reported in the literature, malignant peripheral nerve sheath tumor (MPNST) is a rare primary mesenchymal neoplasm arising in the female genital tract. Most cases occurred in middle-aged adults with high gr...
Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13) [0.03%]
t(7;12)(q36;p13)阳性儿童急性髓系白血病的临床特征和基因特点分析
Anders Östlund,Ahmed Waraky,Anna Staffas et al.
Anders Östlund et al.
Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is a recurrent translocation in AML in infants or very young children and was recently included in the World Health Organization (WHO) Classification of Hematolymphoid Tumors. AML with t(7;...
Microsatellite Instability and Loss of Heterozygosity as Prognostic Markers in Oral Squamous Cell Carcinoma: Molecular Mechanisms, Detection Techniques, and Therapeutic Strategies [0.03%]
微卫星不稳定性及杂合性丧失在口腔鳞状细胞癌中的预后标志:分子机制、检测技术及治疗策略
Leyla Arslan Bozdag,Sevinç Inan,Sibel Elif Gultekin
Leyla Arslan Bozdag
The aim of this study was to conduct a systematic review of research investigating the potential role of microsatellite instability (MSI) and loss of heterozygosity (LOH) in oral squamous cell carcinoma (OSCC), with a focus on molecular mec...
Aggressive Spindle Cell Sarcoma in Young Woman With the FGFR1::EBF2 Fusion [0.03%]
年轻女性FGFR1::EBF2融合基因复发性侵袭性淋巴芽肿样纤维肉瘤病例报告
Harumi Nakamura,Yoji Kukita,Ken-Ichi Yoshida et al.
Harumi Nakamura et al.
Sporadic NF1-Mutated Inflammatory Polyps of the Colon: A Case Report and Brief Literature Review [0.03%]
结肠NF1基因突变所致炎症性息肉的个案报道及文献综述
Azfar Neyaz,Ibrahim Abukhiran,Rana Naous
Azfar Neyaz
Sophie M Constantinou,Dorothy C Bennett
Sophie M Constantinou
Cutaneous malignant melanoma is an aggressive skin cancer with an approximate lifetime risk of 1 in 38 in the UK. While exposure to ultraviolet radiation is a key environmental risk factor for melanoma, up to ~10% of patients report a famil...
Potential Use of Extracellular Vesicles for the HER2 Status Assessment in Breast Cancer Patients [0.03%]
乳腺癌患者HER2状态评估中使用外泌体的潜在作用
Sol Moon,Seung Il Kim,Suji Lee et al.
Sol Moon et al.
Human epithelial growth factor receptor 2 (HER2)-targeted therapies are effective in patients with HER2-positive breast cancer. Recent advances have shown that HER2-targeted therapies can also be of benefit when treating tumors expressing l...
Molecular Profiling of Low-Grade Appendiceal Mucinous Neoplasms (LAMN) [0.03%]
低级别阑尾黏液性肿瘤(LAMN)的分子分型
Julia Doll,Katja Maurus,Franziska Köhler et al.
Julia Doll et al.
Low-grade appendiceal mucinous neoplasia (LAMN) represents a relatively rare tumor of the appendix typically diagnosed incidentally through appendectomy for acute appendicitis. In cases where perforation occurs, mucinous content may dissemi...
Establishment and Characterization of a Novel Pleuropulmonary Blastoma Cell Line [0.03%]
新型胸膜肺母瘤细胞系的建立与特征分析
Keisuke Kato,Hiroaki Goto,Mio Tanaka et al.
Keisuke Kato et al.
Purpose: Pleuropulmonary blastoma (PPB) is an infrequently encountered childhood malignant intrathoracic neoplasm associated with unfavorable clinical behavior. Since a well-characterized preclinical model is essential fo...
MYH9::LTK Fusion in a Pediatric Acral Soft Tissue Spindle Cell Neoplasm [0.03%]
儿童肢端软组织梭形细胞肿瘤中的MYH9::LTK融合基因
Larissa V Furtado,Ana C Polanco,Zonggao Shi et al.
Larissa V Furtado et al.