Scientific Histories of Hippocampal Research: Introduction to the Special Issue Part 2 [0.03%]
关于海马研究的科学史:特刊导论(二)
Michael E Hasselmo,Lynn Nadel
Michael E Hasselmo
This introduction is for the second installment of the special issue on Scientific Histories of Hippocampal Research, with 13 new articles. Part 2 adds to the 24 articles in Part 1, and we expect a third installment in the future. The diffe...
Editorial
Hippocampus. 2026 Mar;36(2):e70079. DOI:10.1002/hipo.70079 2026
Male Rats Carrying the Taiep Mutation Show Alterations in the Dendritic Arborization of CA1 and CA3 Neurons [0.03%]
携带Taiep突变的雄性大鼠CA1和CA3神经元树突分支改变
Fernanda Medina-Flores,Dolores Adriana Bravo-Durán,Ricardo Robles-Soto et al.
Fernanda Medina-Flores et al.
The taiep rat originated from a spontaneous mutation in a colony of Sprague-Dawley rats, whose phenotype is inherited as an autosomal recessive trait. The mutant taiep rat shows hypomyelination and demyelination of the central nervous syste...
Harmonized Protocol for Subfield Segmentation in the Hippocampal Body on High-Resolution In Vivo MRI From the Hippocampal Subfields Group (HSG) [0.03%]
来自海马亚区工作组(HSG)的高分辨率活体MRI下的海马体子区域分割的协调协议
Ana M Daugherty,Valerie Carr,Kelsey L Canada et al.
Ana M Daugherty et al.
Hippocampal subfields differentially develop and age, and they vary in vulnerability to neurodegenerative diseases. Innovation in high-resolution imaging has accelerated clinical research on human hippocampal subfields, but substantial diff...
John OKeefe
John OKeefe
This paper describes the events leading up to the discovery of the place cells in 1971 for which the author received the Nobel Prize in Physiology and Medicine in 2014, together with May-Britt and Edvard Moser. In addition, it explores some...
Updated Neuronal Numbers of the Rat Hippocampal Formation: Redesigning the Hippocampal Model [0.03%]
大鼠海马结构神经元数量的更新:重新设计海马模型
Jon I Arellano,Pasko Rakic
Jon I Arellano
The hippocampal formation is a functional entity that includes the hippocampus, subicular complex, and the entorhinal cortex, and has an essential role in learning and memory, emotional processing, and spatial coding. The well-defined struc...
Glutamate Receptors and Synaptic Plasticity in Health and Disease: A Personal Journey [0.03%]
glutamate受体和突触可塑性在生理和疾病中的作用:个人研究历程
Graham L Collingridge
Graham L Collingridge
I describe my progress in understanding synaptic plasticity in the hippocampus. Over the decades my lab has focused on the roles of glutamate receptors (AMPARs, NMDARs, mGluRs and KARs) and associated signaling molecules in LTP and LTD. Mos...
A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice [0.03%]
新型NLRP3抑制剂AMS-17改善C57Bl/6小鼠轻度脑创伤后的长期增强缺陷
Eric Eyolfson,Luis Bettio,Justin Brand et al.
Eric Eyolfson et al.
Traumatic brain injury (TBI) is a leading cause of long-term disability, with limited effective treatment options. A key factor of TBI pathophysiology is neuroinflammation, which can involve the activation of the nucleotide-binding domain l...
Cognitive Strategy Accounts for Failure on a Relational Memory Task in Non-Human Primates [0.03%]
认知策略导致非人灵长类动物在一种记忆任务中失败
Casey R Vanderlip,Shelby R Dunn,Payton A Asch et al.
Casey R Vanderlip et al.
Relational memory, the ability to flexibly encode and retrieve associations among distinct elements, is critically dependent on the hippocampus and declines with age in humans. The Transverse Patterning (TP) task is designed to probe relati...