Opioid-Associated Hippocampal Injury: Past, Present, and Future Directions [0.03%]
阿片类药物相关海马损伤：过去、现在和未来方向研究进展
Jed A Barash,Joshua Madden,W Andrew Kofke
Jed A Barash
Three of the great public health challenges of our time converge at the hippocampus. The first, dementia, most commonly in the form of Alzheimer's disease, is well known to cause progressive hippocampal damage, resulting in the memory loss ...
Neural and Navigational Features Influencing the Novelty Induced Benefits on Episodic Memory [0.03%]
神经和导航特征对新颖性诱导的事件记忆益处的影响
David A Vogelsang,Carla Maló Calmus,Madeleine Vohs et al.
David A Vogelsang et al.
Studies in animals have robustly shown that exposure to novelty can promote memory for information presented in the temporal vicinity. In humans, however, evidence for such novelty-related memory benefits has been mixed. In this EEG study, ...
Intrinsic Persistent Firing in CA1 Encodes Elapsed Time Across Behaviorally Relevant Scales [0.03%]
CA1固有持续放电在行为相关时间尺度上编码经历的时间
Sara Zomorodi,Beate Knauer,Yacine Brahimi et al.
Sara Zomorodi et al.
The ability to encode and maintain temporal relationships is crucial for learning, predicting, and forming episodic memories. While hippocampal time cells and entorhinal temporal context cells are well-established in vivo, it remains unclea...
Boundary Vector Cells Encode a Future-Biased Spectrum of Positions in the Rat [0.03%]
大鼠边界向量细胞的记录范围偏向未来位置分布
Ehren Lee Newman,Inna Mashanova-Galikova,Zoran Tiganj et al.
Ehren Lee Newman et al.
Spatial tuning is a hallmark property of neural firing in the hippocampal formation. Yet, that tuning is often less well correlated with the instantaneous current position of an animal than it is with an integrated version of the past or fu...
Hippocampal NOP Receptor Activation Impairs Object Recognition Memory Acquisition [0.03%]
海马管NOP受体激活损害目标识别记忆的获得
Lucas Ribeiro,Rodrigo Orvate,Johseph P de Souza et al.
Lucas Ribeiro et al.
Nociceptin/orphanin FQ (N/OFQ), the endogenous ligand of the NOP receptor, modulates learning and memory, yet its precise hippocampal function remains unclear. Here, we examined how activation of hippocampal NOP receptors influences distinc...
Effects of Corticotropin-Releasing Factor 1 Receptor Antagonism on In Vivo Dentate Gyrus Long-Term Potentiation in the TgF344-AD Rat Model of Alzheimer's Disease [0.03%]
催乳素释放肽1受体拮抗在TgF344-AD大鼠海马齿状回的活体内长期增强作用中的影响
Nicole C Reyna,Derek A Hamilton
Nicole C Reyna
Alzheimer's disease (AD) is characterized by irreversible neurobiological deterioration and cognitive impairment. AD patients exhibit stress system abnormalities including upregulation of the corticotropin releasing factor type 1 receptor (...
Quantitative and Morphometric Measures in the Human Hippocampal Tail Using Ex Vivo Imaging Validated With Histology [0.03%]
基于体外影像的海马尾节定量及形态测定并经组织学验证
Anne M Alexander,Emma W Rosenblum,Nathaniel Mercaldo et al.
Anne M Alexander et al.
The human hippocampal tail is the posterior-most portion of the hippocampus and has been implicated in brain disorders, such as depression, panic disorder, and epilepsy. The tail's clinical relevance and volumetric variability exhibit a nee...
Su-Min Lee,Inah Lee
Su-Min Lee
The subiculum, a key component of the medial temporal lobe (MTL), has traditionally been viewed as a relay station for hippocampal output to cortical regions. However, its intricate afferent and efferent connections with diverse brain areas...
Micro-Stimulation Timing Framed Around an Averaged Theta Period of Stimulation Determines Hippocampal Recruitment in Cued Fear Conditioning [0.03%]
以刺激的平均θ周期为框架的微刺激时间决定海马在信号恐惧条件反射中的动员程度
Paula Gonçalves Vieira Teixeira,Leonardo de Oliveira Guarnieri,Grace Schenatto Pereira et al.
Paula Gonçalves Vieira Teixeira et al.
The importance of precise timing of neuronal activity, relative to ongoing slower oscillations, is reshaping the engram theory and our understanding of how memories are encoded and stored. The hippocampal theta-wave phase-encoding of neuron...
Pharmacological Profile of Early Sharp Waves in the Neonatal Rat Hippocampus [0.03%]
新生大鼠海马早期尖峰波的药理学特征
Dmitrii Shipkov,Daria Vinokurova,Karina Tukhvatullina et al.
Dmitrii Shipkov et al.
Early activity patterns support the development of neuronal networks by promoting synaptic plasticity. In the hippocampus of neonatal rats and mice in vivo, early sharp waves (eSPWs) are the first pattern of synchronized network activity. T...