Donepezil Reverses Alcohol-Induced Changes in Hippocampal Neurogenic and Glial Responses Following Adolescent Intermittent Ethanol Exposure Into Adulthood in Female Rats [0.03%]
-donepezil逆转青春期间歇性乙醇暴露至成年大鼠海马神经发生和胶质反应的酒精诱导变化
Kala N Nwachukwu,James C Nelson,Kennedy M Hill et al.
Kala N Nwachukwu et al.
Adolescent intermittent ethanol (AIE) exposure leads to persisting increases in glial markers and significantly decreases the neurogenic niche in the dentate gyrus of the hippocampus. Our previous study indicated that donepezil (DZ), a chol...
Perinatal Protein Restriction Induces Anhedonic-Like Behavior: Disturbed Hippocampal Neurotrophic Signaling and Neuronal Structural Plasticity in Adult Offspring [0.03%]
围产期蛋白限制导致后代出现快感缺乏行为：海马神经营养信号及神经结构可塑性异常
María C Gutiérrez,Ramiro G Comas Mutis,María C Perondi et al.
María C Gutiérrez et al.
Early protein malnutrition has been shown to affect the brain reward circuitry, leading to enduring molecular, neurochemical, and behavioral alterations. This study explored how maternal protein restriction contributes to anhedonia, a key d...
Scientific Histories of Hippocampal Research: Introduction to the Special Issue [0.03%]
有关海马研究的科学史：特刊导言
Michael E Hasselmo,Lynn Nadel
Michael E Hasselmo
Numerous scientific advances and discoveries have arisen from research on the hippocampal formation. This special issue provides first-person historical descriptions of these advances and discoveries in hippocampal research, written by thos...
Elizabeth A Buffalo
Elizabeth A Buffalo
During the 1990s and early 2000s, research in humans and in the nonhuman primate model of human amnesia revealed that tasks involving free viewing of images provided an exceptionally sensitive measure of recognition memory. Performance on t...
John L Kubie
John L Kubie
In 1979, I joined Jim Ranck's group in Brooklyn and began recording hippocampal neurons. The first project was to record single neurons across three behaviors in different chambers: pellet retrieval on a radial-arm maze, bar-pressing for fo...
Development of the SPEAR Model: Separate Phases of Encoding and Retrieval Are Necessary for Storing Multiple Overlapping Associative Memories [0.03%]
SPEAR模型的建立：存储多个重叠联想记忆需要编码和检索分开进行
Michael E Hasselmo
Michael E Hasselmo
In keeping with the historical focus of this special issue of Hippocampus, this paper reviews the history of my development of the SPEAR model. The SPEAR model proposes that separate phases of encoding and retrieval (SPEAR) allow effective ...
The Anatomy of Context [0.03%]
情境的构成要素分析
Rebecca D Burwell
Rebecca D Burwell
For most of my career, I focused on understanding how and where spatial context, the place where things happen, is represented in the brain. My interest in this began in the early 1990's, during my postdoctoral training with David Amaral, w...
Helen E Scharfman
Helen E Scharfman
For many years, the hilus of the dentate gyrus (DG) was a mystery because anatomical data suggested a bewildering array of cells without clear organization. Moreover, some of the anatomical information led to more questions than answers. Fo...
Richard G M Morris
Richard G M Morris
As requested by the editors of this special issue of Hippocampus on Scientific Histories of Hippocampal Research, this review provides a detailed personal perspective and historical background on the research involved in a number of finding...
Transcranial Direct Current Stimulation Over Bilateral Temporal Lobes Modulates Hippocampal-Occipital Functional Connectivity and Visual Short-Term Memory Precision [0.03%]
经额叶的重复经颅磁刺激调节双侧海马结构的功能连接性并改善视觉短期记忆精度
Weizhen Xie,Sanikaa Thakurdesai,Sahereh Varastegan et al.
Weizhen Xie et al.
Although the medial temporal lobe (MTL) is traditionally considered a region dedicated to long-term memory, recent neuroimaging and intracranial recording evidence suggests that the MTL also contributes to certain aspects of visual short-te...