Nanoemulsifying drug delivery system to improve the bioavailability of piroxicam [0.03%]
用于提高吡罗昔康生物利用度的纳米乳化药物递送系统
Amira Motawea,Thanaa Borg,Manal Tarshoby et al.
Amira Motawea et al.
Objective: The aim of this study is to develop and characterize self-nanoemulsifying drug delivery system (SNEDDS) of piroxicam in liquid and solid forms to improve its dissolution, absorption and therapeutic efficacy. ...
Electrostatically entrapped colistin liposomes for the treatment of Pseudomonas aeruginosa infection [0.03%]
用于治疗绿脓杆菌感染的静电嵌入粘菌素脂质体疗法
Yang Li,Chengcheng Tang,Enbo Zhang et al.
Yang Li et al.
The potential use of liposomes for the pulmonary delivery of colistin has been hindered by their phospholipid membrane permeability resulting in a very low entrapment of colistin in the liposomes. To increase the entrapment capacity of coli...
Solid lipid nanoparticles surface modified with anti-Contactin-2 or anti-Neurofascin for brain-targeted delivery of medicines [0.03%]
表面修饰抗Contactin-2或抗Neurofascin的固脂纳米粒脑靶向递药研究
Nargess Gandomi,Reyhaneh Varshochian,Fatemeh Atyabi et al.
Nargess Gandomi et al.
Multiple sclerosis (MS) is a chronic central nervous system (CNS) inflammation. Efficient drug delivery to brain is however hampered by blood-brain barrier (BBB). In order to have highly efficient and safe delivery of drugs to brain, solid ...
Comparative release studies on suppositories using the basket, paddle, dialysis tubing and flow-through cell methods I. Acetaminophen in a lipophilic base suppository [0.03%]
比较溶解试验 IV。 acetaminophen 脂溶基肛门栓剂篮法、桨法、渗析管法和流通细胞法
Seiichi Hori,Tsubasa Kawada,Sanae Kogure et al.
Seiichi Hori et al.
The release characteristics of lipophilic suppositories containing acetaminophen (AAP) were examined using four types of dissolution methods: the basket, paddle, dialysis tubing (DT) and flow-through cell (FTC) methods. The suitability of e...
Effect of chitosan coating on microemulsion for effective dermal clotrimazole delivery [0.03%]
壳聚糖包覆对微乳膏有效经皮克霉唑递送的影响研究
Babita Kumari,Karthikeyan Kesavan
Babita Kumari
Clotrimazole (CTZ) is a broad spectrum antimycotic agent known to be very effective locally for the treatment of fungal skin infections. The aim of this study was to study the effect of chitosan-coated microemulsion (CME) for topical delive...
Development of a liquid formulation of poorly water-soluble isosteviol sodium using the co-solvent technology [0.03%]
采用共溶剂技术制备难溶性异甜叶素钠盐液体制剂
Wenshi Lai,Qiuhong Kang,Chengjuan Zou et al.
Wenshi Lai et al.
An intravenously injectable liquid formulation of the poorly water-soluble isosteviol sodium (ISVNa) that has a great clinical potential for cardiovascular diseases was developed using the co-solvent technology. The pH and composition of th...
Nystatin and lidocaine pastilles for the local treatment of oral mucositis [0.03%]
制备用于口腔黏膜炎局部治疗的纳他霉素和利多卡因片剂的研究
Filipa Cosme Silva,Joana M Marto,Ana Salgado et al.
Filipa Cosme Silva et al.
Oral mucositis (OM) is a common adverse reaction to radiotherapy and chemotherapy in oncology. Its treatment requires oral formulations that enhance therapy compliance, improve administration and ensure drug effectiveness. Solid dosage form...
Nonionic surfactant structure on the drug release, formulation and physical properties of ethylcellulose microspheres [0.03%]
非离子型表面活性剂结构对乙基纤维素微球的药物释放、配方和物理性质的影响
Mohan Thakare,Bridg&#x;ette Israel,Solomon Garner et al.
Mohan Thakare et al.
Evaluate the effects of nonionic surfactants Brij 58 and Tween 40 with different structures but similar hydrophilic lipophilic balances (HLBs) on theophylline (TH)-loaded ethylcellulose (EC) microspheres. Microspheres were formulated using ...
Host-guest inclusion system of rhein with polyamine-modified β-cyclodextrins: characterization and cytotoxicity [0.03%]
番木鳖碱与聚胺修饰的β-环糊精主客体包合物体系的构建及性质研究
Pin Lv,Manshuo Liu,Rongqiang Liao et al.
Pin Lv et al.
We report the preparation of inclusion complexes between rhein and four polyamine-modified β-cyclodextrins, namely amino-β-cyclodextrins (NH2-βCD), ethylenediamine-β-cyclodextrins (EN-βCD), diethylenetriamine-β-cyclodextrins (DETA-βC...
Preparation of a reproducible long-acting formulation of risperidone-loaded PLGA microspheres using microfluidic method [0.03%]
使用微流控方法制备利培酮载药PLGA微球长效可重复仿制制剂
Elham Jafarifar,Marziyeh Hajialyani,Mona Akbari et al.
Elham Jafarifar et al.
The aim of the present study is to prepare risperidone-loaded poly lactic-co-glycolic acid (PLGA) microspheres within microfluidic system and to achieve a formulation with uniform size and monotonic and reproducible release profile. In comp...