Development and optimization of a meloxicam/β-cyclodextrin complex for orally disintegrating tablet using statistical analysis [0.03%]
基于统计分析的口服速释片用美洛昔康/β环糊精包合物的开发及优化研究
Ahmad Ainurofiq,Syaiful Choiri
Ahmad Ainurofiq
The purpose of this research was to develop an inclusion complex of meloxicam (MEL)/β-cyclodextrin (β-CD) incorporated into an orally disintegrating tablet (ODT), using statistical analysis to optimize the ODT formulation based on a quali...
Formulation, characterization, and in vitro/ex vivo evaluation of quercetin-loaded microemulsion for topical application [0.03%]
一种用于局部给药的檞皮素载药微乳液的制备、表征及体外/离体评价研究
Azar Kajbafvala,Alireza Salabat,Anayatollah Salimi
Azar Kajbafvala
The aim of this study was to develop a new microemulsion formulation for topical application of poorly soluble drug named quercetin. In order to design suitable microemulsion system, the pseudo-ternary phase diagrams of microemulsion system...
Physical-chemical properties of furosemide nanocrystals developed using rotation revolution mixer [0.03%]
旋转革命混合器开发的呋塞米纳米晶体的物理化学性质研究
Sávio Fujita Barbosa,Takayuki Takatsuka,Guilherme Diniz Tavares et al.
Sávio Fujita Barbosa et al.
Recently, several approaches have been reported to improve the dissolution rate and bioavailability of furosemide, a class IV drug. However, to the best of our knowledge, none of them proposed nanocrystals. In the last decade, nanocrystals ...
On the inherent properties of Soluplus and its application in ibuprofen solid dispersions generated by microwave-quench cooling technology [0.03%]
关于Soluplus固有性质及其在微波淬冷技术制备的吲哚美辛固体分散体中的应用研究
Nian-Qiu Shi,Hong-Wei Lai,Yong Zhang et al.
Nian-Qiu Shi et al.
Polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer, or Soluplus®, is a relatively new copolymer and a promising carrier of amorphous solid dispersions. Knowledge on the inherent properties of Soluplus® (e.g. cloud...
Correlation between the viscoelastic properties of the gel layer of swollen HPMC matrix tablets and their in vitro drug release [0.03%]
羟丙基甲纤维素缓释片溶胀凝胶层的粘弹性与体外释放相关性研究
Rania Hamed,Tamadur Al Baraghthi,Suhair Sunoqrot
Rania Hamed
Drug release from hydroxypropyl methylcellulose (HPMC) hydrophilic matrix tablets is controlled by drug diffusion through the gel layer of the matrix-forming polymer upon hydration, matrix erosion or combination of diffusion and erosion mec...
Jing Fu,Xiaoxv Dong,Xinbing Yin et al.
Jing Fu et al.
Isoimperatorin is a naturally occurring furocoumarin and is being considered as a potential chemoprevention. Only one crystal form of isoimperatorin (Form I) was reported during previous research so that an investigation of polymorphism of ...
Enhancement of levodopa stability when complexed with β-cyclodextrin in transdermal patches [0.03%]
β-环糊精复方改善透皮贴片中左旋多巴的稳定性
Rana Obaidat,Nizar Al-Shar&#x;i,Bassam Tashtoush et al.
Rana Obaidat et al.
Levodopa is a promising candidate for administration via the transdermal route because it exhibits a short plasma half-life and has a small window of absorption in the upper section of the small intestine. The aim of this study was to prepa...
Concurrent study of stability and cytotoxicity of a novel nanoemulsion system - an artificial neural networks approach [0.03%]
新型纳米乳液体系的稳定性和细胞毒性的同步研究-人工神经网络方法
Negar Seyedhassantehrani,Roya Karimi,Gholamreza Tavoosidana et al.
Negar Seyedhassantehrani et al.
Problems commonly associated with using nanoemulsions are their cytotoxic effects and low stability profiles. Here, for the first time, concentrations of ingredients of a nanoemulsion system were investigated to obtain the most stable nanoe...
Preparation and optimization of glyceryl behenate-based highly porous pellets containing cilostazol [0.03%]
含西洛他唑甘油 behenate 基高度多孔微丸的制备及优化
Kyu-Mok Hwang,Woojin Byun,Cheol-Hee Cho et al.
Kyu-Mok Hwang et al.
The aim of this study was to prepare a highly porous multiparticulate dosage form containing cilostazol for gastroretentive drug delivery. The floating pellets were prepared with glyceryl behenate as a matrix former and camphor as a sublima...
Development and effect of storage on the stability of enriched flavonoid fraction of Cecropia glaziovii-loaded PLGA nanoparticles [0.03%]
负载Cecropia glaziovii富黄酮组分的PLGA纳米粒的制备及其贮藏稳定性研究
Talitha Caldas Dos Santos,Mariana Alves Battisti,Caroline Flach Ortmann et al.
Talitha Caldas Dos Santos et al.
Studies employing Cecropia glaziovii Snethl leaves have shown great potential in regard to their antiviral activity, mainly related to the phenolic compounds present in this species. The main goal of this work is to combine the therapeutic ...