PRospective Evaluation of the European Society of Cardiology 0/1h-algorithm`s Safety and Efficacy for Triage of Patients with Suspected Myocardial Infarction (PRESC1SE-MI): Rationale and design of a prospective international multicenter stepped-wedge cluster randomized controlled trial [0.03%]
欧洲心脏病学会0/1小时算法用于疑似心肌梗死患者的分诊的安全性与有效性前瞻性评价（PRESC1SE-MI）：前瞻性国际多中心分阶段群体随机对照试验的设计与理由
Jasper Boeddinghaus,Paolo Bima,Luca Crisanti et al.
Jasper Boeddinghaus et al.
Background: International practice guidelines recommend the more rapid European Society of Cardiology (ESC) 0/1h-algorithm for the triage of patients with suspected myocardial infarction (MI) as the preferred option and c...
Routine versus selective protamine administration to reduce bleeding after TAVI: Rationale and Design of the POPular ACE TAVI trial [0.03%]
万古霉素治疗耐甲氧西林金黄色葡萄球菌感染的药代动力学-药效学模型指导的最佳药物暴露：一项模拟研究
Daniël C Overduin,Dirk Jan van Ginkel,Christophe Dubois et al.
Daniël C Overduin et al.
Background: Unfractionated heparin is routinely used during transcatheter aortic valve implantation (TAVI) to reduce catheter thrombosis and thromboembolism. Protamine reverses the effect of heparin and may lower bleeding...
Rationale and design of REAC-TAVI 2: single antiplatelet treatment with ticagrelor versus aspirin after transcatheter aortic valve implantation [0.03%]
REAC-TAVI 2研究的设计和 rationale：TAVI术后替格瑞洛单抗血小板治疗与阿司匹林对照试验
Kimberley Hemelrijk,Victor A Jimenez-Diaz,Jean Paul Vilchez et al.
Kimberley Hemelrijk et al.
Background: Patients undergoing transcatheter aortic valve implantation (TAVI) frequently experience life-threatening ischemic and bleeding complications. However, management of antithrombotic therapy after TAVI in patien...
A Just-In-Time Adaptive Mobile Application Intervention to Reduce Sodium Intake and Blood Pressure in Patients with Hypertension: Rationale and Design of the LowSalt4Life 2 Trial [0.03%]
基于患者的高血压设计和降低钠摄入及血压的即时适应性移动应用程序干预：LowSalt4Life 2试验的原理与设计
Michael P Dorsch,Walter Dempsey,Amy Krambrink et al.
Michael P Dorsch et al.
Introduction: Excess dietary sodium intake is a major contributor to hypertension (HTN) and cardiovascular disease in the U.S., yet most Americans exceed recommended sodium intake levels. Despite the established benefits ...
Association of obesity subphenotypes with indices of cardiac remodeling in the Framingham Heart Study [0.03%]
弗明翰心脏研究中肥胖亚表型与心脏重塑指数之间的关联
William J He,Brenton R Prescott,Vanessa Xanthakis et al.
William J He et al.
Background: Previous studies have reported that obesity-related metabolic abnormalities (e.g., diabetes and hypertension) lead to myocardial dysfunction and adverse cardiac remodeling. However, it is unclear whether such ...
Distal versus conventional radial large-bore access for percutaneous coronary intervention of complex coronary lesions: Rationale and design of the DISCO COMPLEX randomized superiority trial [0.03%]
复杂冠状动脉病变患者经皮冠状动脉介入治疗时远端桡动脉通路与常规桡动脉通路的随机对照优势临床试验——DISCO COMPLEX研究：rationale and study design
Juan F Iglesias,Gregor Leibundgut,Dik Heg et al.
Juan F Iglesias et al.
Rationale: Distal radial access (DRA) has emerged as a promising alternative to conventional transradial access (TRA) for coronary angiography and percutaneous coronary intervention (PCI). However, existing randomized evi...
Worsening Heart Failure Events in Adults with Mild-to-Moderate Chronic Kidney Disease [0.03%]
中至重度慢性肾脏病成人的心力衰竭事件恶化
Linda Ye,Michael P Girouard,Alan S Go et al.
Linda Ye et al.
Background: Chronic kidney disease (CKD) is a major risk factor for heart failure (HF). However, the burden of worsening HF (WHF) events among adults with mild-to-moderate CKD has not been well described. ...
Response to letter by Hu regarding article, "Statistical Methodological Limitations and Improvement Suggestions in the Study of Vitamin D Deficiency and Cardiovascular Mortality After Heart Transplantation." [0.03%]
对胡老师来信的回应——关于“心脏移植后维生素D缺乏与心血管死亡研究中的统计方法缺陷及改进建议”一文
Matthew Gold,Sarah Kulkarni,Arshed Quyyumi
Matthew Gold
Response to letter by Naeem regarding article, "Loop and thiazide diuretics and outcomes in heart failure with preserved ejection fraction" [0.03%]
关于“心力衰竭射血分数保留患者使用利尿剂治疗”一文的回信答复Naeem来信中的观点
Barna Szabó-Söderberg,Lars H Lund
Barna Szabó-Söderberg